Journal of Fungi, 2022 Paracoccidioidomycosis (PCM) is the most prevalent systemic mycosis in Brazil. The disease is caused by dimorphic fungi nested within the Paracoccidioides genus.
Alessandra G. Krakhecke-Teixeira +10 more
doaj +1 more source
Paracoccidioides brasiliensis GP43-derived peptides are potent modulators of local and systemic inflammatory response [PDF]
, 2012 Paracoccidioidomycosis is a systemic granulomatous disease caused by the dimorphic fungus Paracoccidioides brasiliensis. Its major antigen is a 43 kDa glycoprotein whose peptides embody different functions: P10 peptide, a T-cell epitope, :induces ...
Feitosa, Luciano dos Santos +7 more
core +2 more sources
Antifungal Potential of Essential Oil Chemotypes of Eugenia uniflora Against Phytopathogens
Chemistry &Biodiversity, Volume 23, Issue 2, February 2026.This study investigates the chemical profile and antifungal activity of Eugenia uniflora essential oils. The major constituents identified were selina‐1,3,7(11)‐trien‐8‐one and curzerene. The oils showed significant inhibitory effects against the phytopathogens Colletotrichum gloeosporioides and Pestalotia sp. These results emphasize the potential of E.
Ygor Nunes Moreira +10 more
wiley +1 more source
Detection of the basement membrane-degrading proteolytic activity of Paracoccidioides brasiliensis after SDS-PAGE using agarose overlays containing Abz-MKALTLQ-EDDnp [PDF]
, 1999 We have characterized, in the Paracoccidioides brasiliensis yeast phase, an exocellular SH-dependent serine proteinase activity against Abz-MKRLTL-EDDnp and analogous fluorescent-quenched peptides, and showed that it is also active against constituents ...
Carmona, Adriana Karaoglanovic +4 more
core +4 more sources
Mycoses, Volume 69, Issue 2, February 2026.ABSTRACT Objective To describe the epidemiology, associated factors, spatial distribution, and temporal trends of mortality and in‐hospital mortality related to systemic mycoses in Brazil, 2000–2024. Methods This is a nationwide ecological study combining temporal and spatial analyses using death certificates (DC; underlying and/or associated causes ...
Anderson Fuentes Ferreira +8 more
wiley +1 more source
Transcriptional and proteomic responses to carbon starvation in Paracoccidioides. [PDF]
PLoS Neglected Tropical Diseases, 2014 BACKGROUND: The genus Paracoccidioides comprises human thermal dimorphic fungi, which cause paracoccidioidomycosis (PCM), an important mycosis in Latin America. Adaptation to environmental conditions is key to fungal survival during human host infection.
Patrícia de Sousa Lima +5 more
doaj +1 more source
New insights into the cell cycle profile of Paracoccidioides brasiliensis [PDF]
, 2006 The present work focuses on the analysis of cell cycle progression of Paracoccidioides brasiliensis yeast cells under diVerent environmental conditions.
Almeida, A. J. +6 more
core +1 more source
Infrared Spectroscopy as a Promising Tool for Diagnosing and Typing Human Pathogenic Fungi
Mycoses, Volume 69, Issue 1, January 2026.ABSTRACT Fungal infections are increasingly recognised as a global health challenge, responsible for millions of cases annually and substantial mortality, especially in immunocompromised individuals. Yet, the diagnosis of these infections remains notoriously difficult, often delayed by slow culture‐based methods or hindered by the high cost and ...
Anthony G. J. Medeiros +8 more
wiley +1 more source
A hidden battle in the dirt: Soil amoebae interactions with Paracoccidioides spp.
PLoS Neglected Tropical Diseases, 2019 Paracoccidioides spp. are thermodimorphic fungi that cause a neglected tropical disease (paracoccidioidomycosis) that is endemic to Latin America. These fungi inhabit the soil, where they live as saprophytes with no need for a mammalian host to complete ...
Patrícia Albuquerque +17 more
doaj +1 more source
DNA vaccine encoding peptide P10 against experimental paracoccidioidomycosis induces long-term protection in presence of regulatory T cells [PDF]
, 2013 Paracoccidioidomycosis is a granulomatous systemic mycosis endemic in Brazil and other Latin America countries. A DNA vaccine encoding the inununoprotective peptide 10 (P10) significantly reduced the fungal burden in mice when given prior to or after ...
Amorim, Juliana de +6 more
core +2 more sources