Results 61 to 70 of about 4,243 (161)
Thoracic Cancer, Volume 16, Issue 2, January 2025.ES‐LUAD exhibits specific enrichment or depletion of certain fungal species, showing significant correlations with host transcription. Additionally, we have developed a fungal consortium that can effectively distinguish between patients with ES‐LUAD and HCs.
Yaohui Sun +9 more
wiley +1 more source
The Significance of Mono‐ and Dual‐Effective Agents in the Development of New Antifungal Strategies
Chemical Biology &Drug Design, Volume 105, Issue 1, January 2025.The future of treating challenging fungal infections lies in novel therapies targeting new antifungal targets, overcoming resistance mechanisms, and exploring innovative dual inhibitors. ABSTRACT Invasive fungal infections (IFIs) pose significant challenges in clinical settings, particularly due to their high morbidity and mortality rates.
Cengiz Zobi, Oztekin Algul
wiley +1 more source
Evaluation of the efficacy of antifungal drugs against Paracoccidioides brasiliensis and Paracoccidioides lutzii in a Galleria mellonella model [PDF]
International Journal of Antimicrobial Agents, 2016 Paracoccidioides brasiliensis and P. lutzii belong to a group of thermodimorphic fungi and cause paracoccidioidomycosis (PCM), which is a human systemic mycosis endemic in South and Central America. Patients with this mycosis are commonly treated with amphotericin B (AmB) and azoles.
de Lacorte Singulani, Junya +4 more
openaire +4 more sources
Imported Systemic Endemic Mycoses in Spain 1997–2021: An Analysis of a National Hospital Database
Mycoses, Volume 68, Issue 1, January 2025.ABSTRACT Background Systemic endemic mycoses are systemic fungal infections typically found in tropical and subtropical regions. Their global incidence is rising, including in nonendemic countries, mainly due to migration and international travel. They are a major cause of morbidity and mortality worldwide, especially in immunocompromised patients ...
Jara Llenas‐García +3 more
wiley +1 more source
Interdisciplinary Perspectives on Infectious Diseases, Volume 2025, Issue 1, 2025.Background: The complex interplay between the human genome and microbial pathogens has captured scientific interest, leading to profound insights into the genetic basis of host’s susceptibility to infections. Objective: Here, we explore the spectrum of genetic susceptibility in infectious diseases, ranging from common single nucleotide polymorphisms ...
Francesca Conti +17 more
wiley +1 more source
Serology of Paracoccidioidomycosis Due to Paracoccidioides lutzii
PLoS Neglected Tropical Diseases, 2014 Paracoccidioides lutzii is a new agent of paracoccidioidomycosis (PCM) and has its epicenter localized to the Central-West region of Brazil. Serological diagnosis of PCM caused by P. lutzii has not been established. This study aimed to develop new antigenic preparations from P. lutzii and to apply them in serological techniques to improve the diagnosis
Zoilo Pires de Camargo +6 more
openaire +5 more sources
Perspective on donor‐derived infections in Italy
Transplant Infectious Disease, Volume 26, Issue S1, November 2024.Abstract Background Expected and unexpected donor‐derived infections (DDI) are a rare event in solid organ transplant (SOT) recipients but are potentially associated with significant morbidity and mortality. To assure the microbial safety of transplantation, both national guidelines and the current, regional, and local epidemiology of infectious ...
Paolo Antonio Grossi +4 more
wiley +1 more source
Osteomielite pelo Paracoccidioides brasiliensis [PDF]
Revista da Sociedade Brasileira de Medicina Tropical, 2002 Frederico Henrique Corrêa de Melo +2 more
openaire +7 more sources
Species boundaries in the human pathogen Paracoccidioides
Fungal Genetics and Biology, 2017 The use of molecular taxonomy for identifying recently diverged species has transformed the study of speciation in fungi. The pathogenic fungus Paracoccidioides spp has been hypothesized to be composed of five phylogenetic species, four of which compose the brasiliensis species complex.
David A. Turissini +4 more
openaire +3 more sources
Infection and pulmonary vascular diseases consortium: United against a global health challenge
Pulmonary Circulation, Volume 14, Issue 4, October 2024.Abstract Leveraging the potential of virtual platforms in the post‐COVID‐19 era, the Infection and Pulmonary Vascular Diseases Consortium (iPVDc), with the support of the Pulmonary Vascular Research Institute (PVRI), launched a globally accessible educational program to highlight top‐notch research on inflammation and infectious diseases affecting the ...
S. D. Oliveira +11 more
wiley +1 more source