Results 91 to 100 of about 9,487 (202)

Assessing the potential risk of human pathogen resistance to medical antifungal treatments arising from agricultural use of fungicides with the same mode of action

Plant Pathology, Volume 74, Issue 2, Page 578-594, February 2025.
A mechanistic basis is described for assessment of resistance risk to medical antifungal treatments from agricultural use of fungicides of the same mode of action. Abstract A mechanistic basis is described for assessment of resistance risk to medical antifungal treatments from agricultural use of fungicides of the same mode of action.
Neil Paveley, Frank van den Bosch, Michael Grimmer   +2 more
wiley   +1 more source

pancreatic destruction in experimentally infected [PDF]

, 2009
Background The wild rodent Calomys callosus is notably resistant to Trypanosoma cruzi infection. In order to better characterize this animal model for experimental infections, we inoculated C. callosus intraperitoneally with Paracoccidioides brasiliensis,
Junqueira-Kipnis Ana, Kipnis André, Fortes Rogério M   +2 more
core   +1 more source

Antimicrobial Peptides: A Promising Alternative to Conventional Antimicrobials for Combating Polymicrobial Biofilms

Advanced Science, Volume 12, Issue 1, January 9, 2025.
Antimicrobial peptides (AMPs) are promising alternatives to conventional treatments for polymicrobial biofilms, which increase pathogen resistance. AMPs disrupt biofilm extracellular matrices and microbial membranes, inhibiting biofilm formation and enhancing antibiotic efficacy. Current research addresses challenges like stability and production costs
Cesar Augusto Roque‐Borda, Laura Maria Duran Gleriani Primo, Kaila Petronila Medina‐Alarcón, Isabella C. Campos, Camila de Fátima Nascimento, Mauro M. S. Saraiva, Angelo Berchieri Junior, Ana Marisa Fusco‐Almeida, Maria José Soares Mendes‐Giannini, João Perdigão, Fernando Rogério Pavan, Fernando Albericio   +11 more
wiley   +1 more source

Involvement of Dihydrolipoyl Dehydrogenase in the Phagocytosis and Killing of Paracoccidioides brasiliensis by Macrophages

Frontiers in Microbiology, 2017
Paracoccidioides brasiliensis and Paracoccidioides lutzii are fungi causing paracoccidioidomycosis (PCM), an autochthonous systemic mycosis found in Latin America.
Taise N. Landgraf, Marcelo V. Costa, Aline F. Oliveira, Wander C. Ribeiro, Ademilson Panunto-Castelo, Fabrício F. Fernandes   +5 more
doaj   +1 more source

Metagenomic and Transcriptomic Analysis Reveals Crosstalk Between Intratumor Mycobiome and Hosts in Early‐Stage Nonsmoking Lung Adenocarcinoma Patients

Thoracic Cancer, Volume 16, Issue 2, January 2025.
ES‐LUAD exhibits specific enrichment or depletion of certain fungal species, showing significant correlations with host transcription. Additionally, we have developed a fungal consortium that can effectively distinguish between patients with ES‐LUAD and HCs.
Yaohui Sun, Zhiming Gan, Shijiancong Liu, Sheng Zhang, Wei Zhong, Jian Liu, Xiuting Huang, Wei He, Hongcheng Zhong, Qingdong Cao   +9 more
wiley   +1 more source

Paracoccidioidomicose do sistema nervoso central: análise de 13 casos [PDF]

, 2006
Paracoccidioidomycosis (PCM) is a systemic granulomatous disease caused by Paracoccidioides brasiliensis, prevalent in Latin America, particularly in Brazil. Central nervous system (CNS) involvement occur in about 10% of cases. Thirteen patients with PCM
Carvalho, Gervasio Teles Cardoso, Fagundes-Pereyra, Walter J., Góes, Alfredo de Miranda, Silva, Francisco das Chagas Lima e, Sousa, Atos Alves de   +4 more
core   +3 more sources

Imported Systemic Endemic Mycoses in Spain 1997–2021: An Analysis of a National Hospital Database

Mycoses, Volume 68, Issue 1, January 2025.
ABSTRACT Background Systemic endemic mycoses are systemic fungal infections typically found in tropical and subtropical regions. Their global incidence is rising, including in nonendemic countries, mainly due to migration and international travel. They are a major cause of morbidity and mortality worldwide, especially in immunocompromised patients ...
Jara Llenas‐García, Roberto González Beiro, José‐Manuel Ramos‐Rincón, Philip Wikman‐Jorgensen   +3 more
wiley   +1 more source

Comparative genomic analysis of human fungal pathogens causing paracoccidioidomycosis.

PLoS Genetics, 2011
Paracoccidioides is a fungal pathogen and the cause of paracoccidioidomycosis, a health-threatening human systemic mycosis endemic to Latin America. Infection by Paracoccidioides, a dimorphic fungus in the order Onygenales, is coupled with a thermally ...
Christopher A Desjardins, Mia D Champion, Jason W Holder, Anna Muszewska, Jonathan Goldberg, Alexandre M Bailão, Marcelo Macedo Brigido, Márcia Eliana da Silva Ferreira, Ana Maria Garcia, Marcin Grynberg, Sharvari Gujja, David I Heiman, Matthew R Henn, Chinnappa D Kodira, Henry León-Narváez, Larissa V G Longo, Li-Jun Ma, Iran Malavazi, Alisson L Matsuo, Flavia V Morais, Maristela Pereira, Sabrina Rodríguez-Brito, Sharadha Sakthikumar, Silvia M Salem-Izacc, Sean M Sykes, Marcus Melo Teixeira, Milene C Vallejo, Maria Emília Machado Telles Walter, Chandri Yandava, Sarah Young, Qiandong Zeng, Jeremy Zucker, Maria Sueli Felipe, Gustavo H Goldman, Brian J Haas, Juan G McEwen, Gustavo Nino-Vega, Rosana Puccia, Gioconda San-Blas, Celia Maria de Almeida Soares, Bruce W Birren, Christina A Cuomo   +41 more
doaj   +1 more source

Gene knockdown in Paracoccidioides brasiliensis using antisense RNA [PDF]

, 2012
Paracoccidioides brasiliensis is a thermal dimorphic fungus which at host environment exhibits a multinucleated and multibudding yeast form. The cellular and molecular mechanisms underlying these phenotypes remain to be clarified, mostly due to the ...
Almeida, A. J., Menino, João F., Rodrigues, Fernando José dos Santos   +2 more
core   +1 more source

New insights into the cell cycle profile of Paracoccidioides brasiliensis [PDF]

, 2006
The present work focuses on the analysis of cell cycle progression of Paracoccidioides brasiliensis yeast cells under diVerent environmental conditions.
Almeida, A. J., Cano, L. E., Carmona, J. A., Leão, Cecília, Martins, M., Restrepo, A., Rodrigues, Fernando José dos Santos   +6 more
core   +1 more source