Results 71 to 80 of about 9,487 (202)

Characterization of a Paracoccidioides spp. strain from southeastern Brazil genotyped as Paracoccidioides restrepiensis (PS3) and review of this phylogenetic species

Genetics and Molecular Biology
Phylogenetic species of Paracoccidioides brasiliensis complex (S1a and S1b, PS2, PS3, and PS4) and Paracoccidioides lutzii are agents of paracoccidioidomycosis, an endemic fungal disease in Latin America. P. restrepiensis (PS3 genotype) was classified as
Tiago Alexandre Cocio, Erika Nascimento, Marcia R. V. Z. Kress, Eduardo Bagagli, Roberto Martinez   +4 more
doaj   +1 more source

Secreted aspartyl proteinase (PbSap) contributes to the virulence of Paracoccidioides brasiliensis infection. [PDF]

PLoS Neglected Tropical Diseases, 2018
Paracoccidioidomycosis (PCM) is the most prevalent deep mycosis in Latin America and is caused by fungi from the Paracoccidioides genus. Virulence factors are important fungal characteristics that support the development of disease.
Daniele Gonçalves Castilho, Alison Felipe Alencar Chaves, Marina Valente Navarro, Palloma Mendes Conceição, Karen Spadari Ferreira, Luiz Severino da Silva, Patricia Xander, Wagner Luiz Batista   +7 more
doaj   +1 more source

Road-killed wild animals: a preservation problem useful for eco-epidemiological studies of pathogens [PDF]

, 2010
Road-killed wild animals have been for years used for surveillance of vectors of zoonotic pathogens and may offer new opportunities for eco-epidemiological studies.
BAGAGLI, E, BARROZO, L, BOSCO, SMG, RICHINI-PEREIRA, VB, THEODORO, RC   +4 more
core   +2 more sources

Fungal DNA‐barcoding on a chip: Magnetoresistive biosensors for yeast infection diagnosis

VIEW, Volume 6, Issue 6, December 2025.
The development of a fungal pathogen identification chip is herein demonstrated. Hybridization dynamics were tested against 58 species in silico and 4 species on chip. 95% accuracy, 91% sensitivity, 98% specificity and femtomolar limit of detection were achieved. Future perspectives include the integration of sample pre‐treatment modules.
Maria Zolotareva, Francisco Cascalheira, Rúben Afonso, Maria Corado, Ana Martins, Cátia Caneiras, Cristina Bárbara, Miguel Cacho Teixeira, Diogo Miguel Caetano   +8 more
wiley   +1 more source

Phylogenetic Species of Paracoccidioides spp. Isolated from Clinical and Environmental Samples in a Hyperendemic Area of Paracoccidioidomycosis in Southeastern Brazil

Journal of Fungi, 2020
Paracoccidioides brasiliensis complex and P. lutzii are the etiological agents of paracoccidioidomycosis. The geographic distribution of these species in South America is still poorly comprehended. Fifty samples of Paracoccidioides spp.
Tiago A. Cocio, Erika Nascimento, Marcia R. von Zeska Kress, Eduardo Bagagli, Roberto Martinez   +4 more
doaj   +1 more source

Flagellins as Vaccine Adjuvants and Cancer Immunotherapy: Recent Advances and Future Prospects

Immunology, Volume 176, Issue 3, Page 277-303, November 2025.
The figure depicts the role of flagellin in immune cells. Flagellin interacts with TLR5, resulting in the formation of homodimers and the recruitment of MyD88, which activates the IκB and MAPK signalling pathways. This results in the activation of NF‐κB and AP‐1, producing TNF‐α, IL‐6, IL‐8, and IL‐12.
Asma Talukder, Md. Mijanur Rahman, Md. Sifat Rahi, Dean L. Pountney, Ming Q. Wei   +4 more
wiley   +1 more source

Overinfection by Paracoccidioides brasiliensis in Gouty Crystal Arthritis

Case Reports in Medicine, 2012
Paracoccidioidomycosis is an endemic South American systemic mycosis caused by the dimorphic fungus Paracoccidioides brasiliensis (P. brasiliensis). The main clinical form of disease is pulmonary, but all organs may be involved.
F. Bonilla-Abadía, J. D. Vélez, L. C. Zárate-Correa, E. Carrascal, N. Guarín, C. R. Castañeda-Ramírez, C. A. Cañas   +6 more
doaj   +1 more source

Kinetics of IFN-gamma, TNF-alpha, IL-10 and IL-4 production by mononuclear cells stimulated with gp43 peptides, in patients cured of paracoccidioidomycosis Cinética da produção de IFN-gama, TNF-alfa, IL-10 e IL-4 por células mononucleares, de pacientes curados de paracoccidoidomicose, estimuladas com peptídeos da gp43

Revista da Sociedade Brasileira de Medicina Tropical, 2007
We analyzed the kinetics of cytokine production by mononuclear cells from 17 patients who had been treated for paracoccidioidomycosis, using the stimulus of gp43 peptide groups (43kDa glycoprotein of Paracoccidioides brasiliensis) at 0.1 and 1µM, gp43 ...
Aya Sadahiro, Constancia Lima Diogo, Telma Miyuki Oshiro, Maria Aparecida Shikanai-Yasuda   +3 more
doaj   +1 more source

Semi-nested PCR para a detecção molecular de Paracoccidioides brasiliensis em amostras de tecido [PDF]

, 2010
INTRODUCTION: Paracoccidioidomycosis is a systemic infection caused by Paracoccidioides brasiliensis. METHODS: In this study, a semi-nested PCR for paracoccidioidomycosis diagnosis was developed. The primers ITS1 and ITS4 were used in the first reaction,
Dionízio Filho, Pedro Sebastião Raimundo, Felipe, Maria Sueli Soares, Koishi, Andrea Cristine, Sasaki, Alexandre Augusto, Venancio, Emerson José, Vituri, Débora Fonseca   +5 more
core   +1 more source

Extracellular Vesicles From Fungal Infection in Humans: A Key Player in Immunological Responses

Journal of Extracellular Biology, Volume 4, Issue 8, August 2025.
ABSTRACT Fungal infections cause approximately 1.6 million deaths annually. Diagnosing and treating fungal infections is difficult due to limited access to diagnostic tests and rising antifungal resistance. Extracellular vesicles (EVs) facilitate interactions between fungal cells and hosts, significantly influencing the pathogen‐host relationship ...
Caroline P. de Rezende, Patrick W. S. Santos, Renan A. Piraine, Virgínia C. Silvestrini, Julio C. J. Barbosa, Fabiana C. P. Valera, Edwin Tamashiro, Guilherme G. Podolski‐Gondim, Silvana M. Quintana, Rodrigo Calado, Roberto Martinez, Taicia P. Fill, Márcio L. Rodrigues, Fausto Almeida   +13 more
wiley   +1 more source