Results 51 to 60 of about 9,487 (202)

DNA vaccine encoding peptide P10 against experimental paracoccidioidomycosis induces long-term protection in presence of regulatory T cells [PDF]

, 2013
Paracoccidioidomycosis is a granulomatous systemic mycosis endemic in Brazil and other Latin America countries. A DNA vaccine encoding the inununoprotective peptide 10 (P10) significantly reduced the fungal burden in mice when given prior to or after ...
Amorim, Juliana de, Magalhães, Adriana, Munoz, Julian Esteban, Nosanchuk, Joshua Daniel, Rittner, Glauce Mary Gomes, Taborda, Carlos Pelleschi, Travassos, Luiz Rodolpho   +6 more
core   +2 more sources

The Hemoprotein Hhy1 Promotes Heme‐Dependent Catalase Activity of Ctt1

Molecular Microbiology, Volume 125, Issue 5, Page 389-411, May 2026.
A Schizosaccharomyces pombe strain deficient in heme (hem1Δ) and siderophore (Fc) biosynthesis, as well as high‐affinity iron (Fe) uptake (blue), was used to uncover the hemoprotein Hhy1 that promotes the heme‐dependent activity of the catalase Ctt1. In contrast, hhy1Δ cells exhibit reduced Ctt1 activity and increased sensitivity to oxidative stress ...
Tobias Vahsen, Samuel Plante, Berthy Mbuya, Simon Labbé   +3 more
wiley   +1 more source

Comprometimento pulmonar pelo paracoccidioides brasiliensis

Research, Society and Development, 2023
Paracoccidioidomicose (PCM) é doença granulomatosa sistêmica que pode comprometer qualquer órgão, principalmente pulmões. O presente artigo tem por objetivo realizar uma revisão da literatura sobre o acometimento pulmonar na infecção por P. brasiliensis, abordando aspectos fisiopatológicos, os métodos diagnósticos e a conduta terapêutica mais adequada ...
Caio César Jorge Fonseca, Lucca de Lima Medeiros, Romária Emanuela Carvalho Santos Soares, Ana Cristina Doria dos Santos   +3 more
openaire   +1 more source

Molecular Phylogenetic Analysis of Paracoccidioides Species Complex Present in Paracoccidioidomycosis Patient Tissue Samples

Microorganisms, 2023
Paracoccidioidomycosis (PCM) is the main and most prevalent systemic mycosis in Latin America, that until recently, it was believed to be caused only by Paracoccidioides brasiliensis (P. brasiliensis). In 2006, researchers described three cryptic species:
Luciana Bonome Zeminian de Oliveira, Amanda Manoel Della Coletta, Taiane Priscila Gardizani, Hans Garcia Garces, Eduardo Bagagli, Luciana Trilles, Ligia Vizeu Barrozo, Sílvio de Alencar Marques, Julio De Faveri, Luciane Alarcão Dias-Melicio   +9 more
doaj   +1 more source

The Homeostasis of Iron, Copper, and Zinc in Paracoccidioides Brasiliensis, Cryptococcus Neoformans Var. Grubii, and Cryptococcus Gattii: A Comparative Analysis [PDF]

, 2011
Iron, copper, and zinc are essential for all living organisms. Moreover, the homeostasis of these metals is vital to microorganisms during pathogenic interactions with a host.
Alexandre Melo Bailão, Augusto Schrank, Charley Christian Staats, Clayton Luiz Borges, Célia Maria de Almeida Soares, Elisa Flávia L.C. Bailão, Joshua D. Nosanchuk, Juliana Alves Parente, Lívia Kmetzsch Rosa e Silva, Maria José Soares Mendes-Giannini, Marilene Henning Vainstein, Maristela Pereira, Mirelle Garcia Silva, Rosely Maria Zancopé Oliveira, Silvia Maria Salem-Izacc   +14 more
core   +2 more sources

Clinical Patterns of Osteoarticular, Bone Marrow and Urogenital Paracoccidioidomycosis

Mycoses, Volume 69, Issue 5, May 2026.
ABSTRACT Background Paracoccidioidomycosis (PCM) is an endemic systemic mycosis in Latin America, classically characterized by pulmonary, mucosal and lymphatic involvement. Extrapulmonary manifestations affecting uncommon organs remain poorly characterized and may contribute to diagnostic delay and adverse outcomes. Methods We conducted a retrospective
Wdson Luis Lima Kruschewsky, Mariane Cappellini Stricagnolo, Mônica Scarpelli Martinelli Vidal, Gil Benard, Vítor Falcão de Oliveira, Tiago Alexandre Cocio, Adriana Satie Gonçalves Kono Magri, Marcello Mihailenko Chaves Magri   +7 more
wiley   +1 more source

Complexo primário da paracoccidioidomicose e hipereosinofilia Primary complex of paracoccidioidomycosis and hypereosinophilia

Jornal Brasileiro de Pneumologia, 2009
A infecção primária por Paracoccidioides brasiliensis é observada raramente. Um paciente masculino de 28 anos de idade apresentou febre, sintomas respiratórios e indisposição durante três meses. Exames radiológicos evidenciaram infiltrado pulmonar apical
Roberto Martinez, Maria Janete Moya
doaj   +1 more source

Antifungal and antitumor models of bioactive protective peptides [PDF]

, 2009
Peptides are remarkably reactive molecules produced by a great variety of species and able to display a number of functions in uni-and multicellular organisms as mediators, agonists and regulating substances. Some of them exert cytotoxic effects on cells
Dobroff, Andrey Sergee, Rodrigues, Elaine Guadelupe, Taborda, Carlos Pelleschi, Travassos, Luiz Rodolpho   +3 more
core   +3 more sources

Helminths as architects of trained tolerance: implications for human health

Clinical &Translational Immunology, Volume 15, Issue 3, 2026.
Abstract Helminths infect nearly 2 billion people worldwide and are a major cause of chronic morbidity in low‐resource regions. Unlike bacterial and viral pathogens that elicit protective memory, helminths actively remodel host immunity to enable their years‐long persistence and reinfection.
Quinn Moroz, Jorge Lucas Nascimento Souza, Neima Briggs   +2 more
wiley   +1 more source

REACTIVITY OF ANTI-GP43 ANTIBODIES FROM PARACOCCIDIOIDES BRASILIENSIS ANTISERUM WITH EXTRACTS FROM CUTANEOUS LESIONS OF LOBO'S DISEASE: PRELIMINARY NOTE

Revista do Instituto de Medicina Tropical de São Paulo, 1997
We demonstrated through several immunochemical tests the presence of GP-43 from P. brasiliensis in extracts of cutaneous lesions from Jorge Lobo's disease.
Mônica Scarpelli Martinelli VIDAL, Selma Aliotti PALACIOS, Natalina TAKAHASHI DE MELO, Carlos da Silva LACAZ   +3 more
doaj   +1 more source