Results 61 to 70 of about 32,242 (205)

Characterization of a Paracoccidioides spp. strain from southeastern Brazil genotyped as Paracoccidioides restrepiensis (PS3) and review of this phylogenetic species

open access: yesGenetics and Molecular Biology
Phylogenetic species of Paracoccidioides brasiliensis complex (S1a and S1b, PS2, PS3, and PS4) and Paracoccidioides lutzii are agents of paracoccidioidomycosis, an endemic fungal disease in Latin America. P. restrepiensis (PS3 genotype) was classified as
Tiago Alexandre Cocio   +4 more
doaj   +1 more source

Microdilution procedure for antifungal susceptibility testing of Paracoccidioides brasiliensis to amphotericin b and itraconazole

open access: yesJournal of Venomous Animals and Toxins including Tropical Diseases, 2009
In vitro tests employing microdilution to evaluate fungal susceptibility to antifungal drugs are already standardized for fermentative yeasts. However, studies on the susceptibility of dimorphic fungi such as Paracoccidioides brasiliensis employing this ...
E Takahagi-Nakaira   +2 more
doaj   +1 more source

Secreted aspartyl proteinase (PbSap) contributes to the virulence of Paracoccidioides brasiliensis infection. [PDF]

open access: yesPLoS Neglected Tropical Diseases, 2018
Paracoccidioidomycosis (PCM) is the most prevalent deep mycosis in Latin America and is caused by fungi from the Paracoccidioides genus. Virulence factors are important fungal characteristics that support the development of disease.
Daniele Gonçalves Castilho   +7 more
doaj   +1 more source

The Hemoprotein Hhy1 Promotes Heme‐Dependent Catalase Activity of Ctt1

open access: yesMolecular Microbiology, Volume 125, Issue 5, Page 389-411, May 2026.
A Schizosaccharomyces pombe strain deficient in heme (hem1Δ) and siderophore (Fc) biosynthesis, as well as high‐affinity iron (Fe) uptake (blue), was used to uncover the hemoprotein Hhy1 that promotes the heme‐dependent activity of the catalase Ctt1. In contrast, hhy1Δ cells exhibit reduced Ctt1 activity and increased sensitivity to oxidative stress ...
Tobias Vahsen   +3 more
wiley   +1 more source

Clinical Patterns of Osteoarticular, Bone Marrow and Urogenital Paracoccidioidomycosis

open access: yesMycoses, Volume 69, Issue 5, May 2026.
ABSTRACT Background Paracoccidioidomycosis (PCM) is an endemic systemic mycosis in Latin America, classically characterized by pulmonary, mucosal and lymphatic involvement. Extrapulmonary manifestations affecting uncommon organs remain poorly characterized and may contribute to diagnostic delay and adverse outcomes. Methods We conducted a retrospective
Wdson Luis Lima Kruschewsky   +7 more
wiley   +1 more source

Phylogenetic Species of Paracoccidioides spp. Isolated from Clinical and Environmental Samples in a Hyperendemic Area of Paracoccidioidomycosis in Southeastern Brazil

open access: yesJournal of Fungi, 2020
Paracoccidioides brasiliensis complex and P. lutzii are the etiological agents of paracoccidioidomycosis. The geographic distribution of these species in South America is still poorly comprehended. Fifty samples of Paracoccidioides spp.
Tiago A. Cocio   +4 more
doaj   +1 more source

Helminths as architects of trained tolerance: implications for human health

open access: yesClinical &Translational Immunology, Volume 15, Issue 3, 2026.
Abstract Helminths infect nearly 2 billion people worldwide and are a major cause of chronic morbidity in low‐resource regions. Unlike bacterial and viral pathogens that elicit protective memory, helminths actively remodel host immunity to enable their years‐long persistence and reinfection.
Quinn Moroz   +2 more
wiley   +1 more source

Kinetics of IFN-gamma, TNF-alpha, IL-10 and IL-4 production by mononuclear cells stimulated with gp43 peptides, in patients cured of paracoccidioidomycosis Cinética da produção de IFN-gama, TNF-alfa, IL-10 e IL-4 por células mononucleares, de pacientes curados de paracoccidoidomicose, estimuladas com peptídeos da gp43

open access: yesRevista da Sociedade Brasileira de Medicina Tropical, 2007
We analyzed the kinetics of cytokine production by mononuclear cells from 17 patients who had been treated for paracoccidioidomycosis, using the stimulus of gp43 peptide groups (43kDa glycoprotein of Paracoccidioides brasiliensis) at 0.1 and 1µM, gp43 ...
Aya Sadahiro   +3 more
doaj   +1 more source

Demystifying fungal systematics: A gateway to fungal literacy and societal/ecological relevance through familiar species

open access: yesPLANTS, PEOPLE, PLANET, Volume 8, Issue 2, Page 499-515, March 2026.
Fungal systematics can feel overwhelming given the vast species diversity within this kingdom, with numerous subgroups at every taxonomic rank. This often creates a disconnect between the undertsnidng of fungal taxonomic diversity and their societal relevance.
Anna Vaiana   +4 more
wiley   +1 more source

Chlamydospore formation by Paracoccidioides brasiliensis mycelial form [PDF]

open access: yesRevista do Instituto de Medicina Tropical de São Paulo, 1989
To investigate the role of some adverse environmental conditions in chlamy-dospore formation by the mycelial form of P. brasiliensis, we cultured four P. brasiliensis isolates (18, Bt4, 1183, Pb9) at 25°C within solid agar medium either rich or poor in nutrients.
Franco, M.   +5 more
openaire   +6 more sources

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