Detection of the basement membrane-degrading proteolytic activity of Paracoccidioides brasiliensis after SDS-PAGE using agarose overlays containing Abz-MKALTLQ-EDDnp [PDF]
, 1999 We have characterized, in the Paracoccidioides brasiliensis yeast phase, an exocellular SH-dependent serine proteinase activity against Abz-MKRLTL-EDDnp and analogous fluorescent-quenched peptides, and showed that it is also active against constituents ...
Rosana Puccia +4 more
openalex +6 more sources
Molecular eco-epidemiology of Paracoccidioides brasiliensis in road-killed mammals reveals Cerdocyon thous and Cuniculus paca as new hosts harboring this fungal pathogen. [PDF]
PLoS ONE, 2021 Wild animals infected with Paracoccidioides brasiliensis represent important indicators of this fungal agent presence in the environment. The detection of this pathogen in road-killed wild animals has shown to be a key strategy for eco-epidemiological ...
Bruno de Souza Scramignon-Costa +9 more
doaj +2 more sources
Impact of paracoccin gene silencing on Paracoccidioides brasiliensis Virulence [PDF]
mBio, 2017 Among the endemic deep mycoses in Latin America, paracoccidioidomycosis (PCM), caused by thermodimorphic fungi of the Paracoccidioides genus, is a major cause of morbidity.
Alegre +44 more
core +3 more sources
Metabolic Peculiarities of Paracoccidioides brasiliensis Dimorphism as Demonstrated by iTRAQ Labeling Proteomics. [PDF]
Front Microbiol, 2019 Paracoccidioidomycosis (PCM), a systemic mycosis with a high incidence in Latin America, is caused by thermodimorphic fungi of the Paracoccidioides genus.
Araújo DS +11 more
europepmc +2 more sources
PLoS ONE, 2019 BACKGROUND:Paracoccidioidomycosis (PCM) is a systemic mycosis commonly found in Latin America that is caused by distinct species of Paracoccidioides genus: Paracoccidioides brasiliensis complex (S1, PS2, PS3 and PS4) and Paracoccidioides lutzii.
Cristiane Candida do Amaral +4 more
doaj +2 more sources
Secreted aspartyl proteinase (PbSap) contributes to the virulence of Paracoccidioides brasiliensis infection. [PDF]
PLoS Neglected Tropical Diseases, 2018 Paracoccidioidomycosis (PCM) is the most prevalent deep mycosis in Latin America and is caused by fungi from the Paracoccidioides genus. Virulence factors are important fungal characteristics that support the development of disease.
Daniele Gonçalves Castilho +7 more
doaj +2 more sources
Down-regulation of TUFM impairs host cell interaction and virulence by Paracoccidioides brasiliensis. [PDF]
Sci Rep, 2019 The genus Paracoccidioides consist of dimorphic fungi geographically limited to the subtropical regions of Latin America, which are responsible for causing deep systemic mycosis in humans.
Marcos CM +19 more
europepmc +2 more sources
Variable gp43 Secretion by Paracoccidioides brasiliensis Clones Obtained by Two Different Culture Methods [PDF]
, 2005 The main objectives of this study were to obtain clones of Paracoccidioides brasiliensis by two methods (micromanipulation and plating assay) and to determine if the secretion of the 43-kDa glycoprotein (gp43) is dependent on the clonal culture.
Rodrigo Berzaghi +2 more
openalex +4 more sources
Comparative genomic analysis of human fungal pathogens causing paracoccidioidomycosis. [PDF]
PLoS Genetics, 2011 Paracoccidioides is a fungal pathogen and the cause of paracoccidioidomycosis, a health-threatening human systemic mycosis endemic to Latin America. Infection by Paracoccidioides, a dimorphic fungus in the order Onygenales, is coupled with a thermally ...
Christopher A Desjardins +41 more
doaj +7 more sources
Immunodiagnosis of Paracoccidioidomycosis due to Paracoccidioides brasiliensis Using a Latex Test: Detection of Specific Antibody Anti-gp43 and Specific Antigen gp43 [PDF]
, 2015 BackgroundParacoccidioidomycosis (PCM) is a life-threatening systemic disease and is a neglected public health problem in many endemic regions of Latin America.
Burger, Eva +5 more
core +25 more sources