Results 91 to 100 of about 6,403 (197)

Drug Repurposing for Paracoccidioidomycosis Through a Computational Chemogenomics Framework

Frontiers in Microbiology, 2019
Paracoccidioidomycosis (PCM) is the most prevalent endemic mycosis in Latin America. The disease is caused by fungi of the genus Paracoccidioides and mainly affects low-income rural workers after inhalation of fungal conidia suspended in the air.
A. A. de Oliveira, B. Neves, Lívia C Silva, C. M. Soares, C. Andrade, M. Pereira   +5 more
semanticscholar   +1 more source

Paracoccidioidomycosis after Highway Construction, Rio de Janeiro, Brazil

Emerging Infectious Diseases, 2017
Transmission of Paracoccidioides spp. fungi to humans is usually related to manipulation of soil. Rural workers are the most affected group. We report an outbreak of paracoccidioidomycosis after deforestation and massive earth removal during construction
A. C. D. do Valle, P. Marques de Macedo, Rodrigo Almeida-Paes, A. R. Romão, M. Lazéra, Bodo Wanke   +5 more
semanticscholar   +1 more source

Profile of total IgG, IgG1, IgG2, IgG3 and IgG4 levels in sera of patients with paracoccidioidomycosis: treatment follow-up using Mexo and rPb27 as antigens in an ELISA

Memorias do Instituto Oswaldo Cruz, 2012
The levels of total of IgG, IgG1, IgG2, IgG3 and IgG4 were evaluated in 54 patients with chronic paracoccidioidomycosis (PCM) before, during and after treatment using an enzyme-linked immunosorbent assay with Mexo and recombinant Pb27 (rPb27) as the ...
Lílian da Silva Santos, Viviane Cristina Fernandes, Samuel Gonçalves da Cruz, Weverton César Siqueira, Alfredo Miranda Goes, Ênio Roberto Pietra Pedroso   +5 more
doaj   +1 more source

Paracoccidioidomicocis: definición de las áreas endémicas de Colombia

Biomédica: revista del Instituto Nacional de Salud, 2000
Una enfermedad endémica es aquélla que se presenta constantemente en un área geográfica o en un grupo de población; la definición de endemia abarca, también, la prevalencia usual de una enfermedad en un área o grupo determinado.
Edilma Torrado, Elizabeth Castañeda, Fernando de la Hoz, Angela Restrepo   +3 more
doaj   +1 more source

Depletion of regulatory T cells in ongoing paracoccidioidomycosis rescues protective Th1/Th17 immunity and prevents fatal disease outcome

Scientific Reports, 2018
In human paracoccidioidomycosis (PCM), a primary fungal infection typically diagnosed when the disease is already established, regulatory T cells (Treg) cells are associated with disease severity.
N. A. L. Galdino, F. V. Loures, E. F. de Araújo, T. A. da Costa, N. Preite, V. Calich   +5 more
semanticscholar   +1 more source

Regulatory T cells in paracoccidioidomycosis

Virulence, 2018
This review addresses the role of regulatory T cells (Tregs), which are essential for maintaining peripheral tolerance and controlling pathogen immunity, in the host response against Paracoccidioides brasiliensis, a primary fungal pathogen.
V. Calich, R. Mamoni, F. V. Loures
semanticscholar   +1 more source

Experimental Therapy of Paracoccidioidomycosis Using P10-Primed Monocyte-Derived Dendritic Cells Isolated From Infected Mice

Frontiers in Microbiology, 2019
Paracoccidioidomycosis (PCM) is an endemic mycosis in Latin American caused by the thermodimorphic fungi of the genus Paracoccidioides spp. Notably, a Th1 immune response is required to control PCM.
Leandro B. R. Silva, Cleison L. Taira, Lucas S. Dias, Ana C. O. Souza, Joshua D. Nosanchuk, Luiz R. Travassos, Carlos P. Taborda, Carlos P. Taborda   +7 more
doaj   +1 more source

Enhanced expression of NLRP3 inflammasome components by monocytes of patients with pulmonary paracoccidioidomycosis is associated with smoking and intracellular hypoxemia.

Microbes and infection, 2019
Paracoccidioidomycosis (PCM) is a systemic mycosis caused by thermally dimorphic fungi of the genus Paracoccidioides that affects predominantly 30-60-year-old male rural workers.
B. C. Amorim, Ana Carla Pereira-Latini, M. de Assis Golim, R. L. Ruiz Júnior, Hugo Hyung Bok Yoo, Maria Sueli Parreira de Arruda, A. Tavares, R. S. Cavalcante, R. P. Mendes, A. Pontillo, J. Venturini   +10 more
semanticscholar   +1 more source

Adrenal Paracoccidioidomycosis [PDF]

The American Journal of Tropical Medicine and Hygiene, 2020
Cataño, Juan, Porras, Jessica
openaire   +2 more sources

Oral paracoccidioidomycosis in a single-center retrospective analysis from a Brazilian southeastern population.

Journal of Infection and Public Health, 2017
BACKGROUND Paracoccidioidomycosis (PCM) is the most prevalent endemic systemic fungal infection in Latin America. In Brazil, it stands out as the eighth-highest cause of mortality among chronic or recurrent infections and has the highest mortality rate ...
L. M. Dutra, T. Silva, A. Falqueto, P. Peçanha, Lúcia Maria Souza, S. S. Gonçalves, T. Velloso   +6 more
semanticscholar   +1 more source