Results 71 to 80 of about 1,188,380 (318)

Optimizing photoactivation of PA‐mCherry for optical pooled CRISPR screens

open access: yesFEBS Open Bio, EarlyView.
Photoactivatable PA‐mCherry finds widespread use to optically tag individual cells. However, confocal 405 nm UV laser‐scanning (normal scan) is much less efficient than widefield UV illumination, limiting the use of PA‐mCherry on confocal instruments. We remedy this limitation by reporting that rapid and repeated confocal scanning with a low‐intensity,
Sravasti Mukherjee   +3 more
wiley   +1 more source

EFFECTIVENESS OF REALIZING PROFESSIONAL SOCIALIZATION OF THE FUTURE PEDAGOGUE THROUGH THE DEVELOPMENT OF THE PROFESSIONAL POSITION

open access: yes, 2018
In the article on the basis of the study of scientific literature, the author attempts to analyze main approaches to the effectiveness of the implementation of professional socialization of the individual through the intensification of the development of
I. V. Firsova, Firsova, I. V.
core   +1 more source

Improved clinical outcome measures of knee pain and function with concurrent resolution of subchondral Bone Marrow Edema Lesion and joint effusion in an osteoarthritic patient following Pentosan Polysulphate Sodium treatment: a case report

open access: yesBMC Musculoskeletal Disorders, 2017
Background At present, there are no registered products for the treatment of subchondral Bone Marrow Edema Lesion (BML) and associated knee pain. Patients who do not respond to current anti-inflammatory therapies are left with limited treatment options ...
Matthew J. Sampson   +5 more
doaj   +1 more source

Acute caffeine treatment protects the developing retina from ischemia‐induced cell death

open access: yesFEBS Open Bio, EarlyView.
Caffeine reduces cell death in the developing retina under ischemia (OGD). This effect does not involve BDNF upregulation or antioxidant pathways (NRF2/VEGF). Neuroprotection occurs mainly through adenosine A2A receptor antagonism, decreasing glutamate release and excitotoxicity, highlighting caffeine's potential as an acute neuroprotective agent in ...
Amanda Alves Nascimento   +6 more
wiley   +1 more source

Instructional Systems Paradigm - Governors State University

open access: yes, 1973
The Instructional Systems Paradigm (ISP) was developed by a University-wide Task Force in response to a charge from the University Assembly to develop a paradigm that would, among other things, ••• provide some elaboration of the sequence of steps ...
Instructional Systems Paradigm Task Force,
core  

Early‐life high‐fat diet exposure increases Achilles tendon stiffness and induces transcriptomic alterations

open access: yesFEBS Open Bio, EarlyView.
Early‐life exposure to a high‐fat diet altered intact Achilles tendons in rat offspring, making them thinner, stiffer, and molecularly distinct even without injury. These findings suggest that developmental high‐fat diet exposure may impair tendon quality and increase susceptibility to mechanical overload or tendon injury later in life.
Heyong Yin   +3 more
wiley   +1 more source

ОСНОВНІ ЗАСАДИ МЕТОДОЛОГІЇ СУЧАСНИХ ЕТНОМУЗИКОЗНАВЧИХ ДОСЛІДЖЕНЬ (ТЕОРІЯ ПІСЕННОЇ ПАРАДИГМИ І МОДУСУ МИСЛЕННЯ СЕРЕДОВИЩА С. ГРИЦИ ТА РИТМОСТРУКТУРНИЙ МЕТОД М. ХАЯ)

open access: yes, 2015
        У даній статті здійснено спробу окреслити засади методології сучасних етномузикознавчих досліджень, зокрема – теорії пісенної парадигми і модусу мислення середовища й семіологічного аспектів етномузикознавиці Софії Грици та ритмоструктурного ...
Охманюк, В. Ф.
core  

Discrete Unilateral Constrained Extended Kalman Filter in an Embedded System

open access: yesSensors
Since its publication in the 1960s, the Kalman Filter (KF) has been a powerful tool in optimal state estimation. However, the KF and most of its variants have mainly focused on the state estimation of smooth systems.
Leonardo Herrera   +1 more
doaj   +1 more source

Emerging insights into CC and CXC chemokines and their receptors in Mycobacterium tuberculosis infection

open access: yesFEBS Open Bio, EarlyView.
The dual roles of CC and CXC chemokines in distinguishing active, latent, and subclinical tuberculosis were reviewed, along with an evaluation of their potential as diagnostic biomarkers and therapeutic targets to advance precision medicine in tuberculosis management. The graphical abstract was generated with AI assistance (Gemini 3.0).
Xuying Yin, Dangsheng Xiao, Jiezuan Yang
wiley   +1 more source

Service Architecture Paradigm

open access: yes, 2007
. The main objective of the Image Indexing by Content network (I 2 Cnet) is to provide network-transparent content-based access to medical image archives based on a collection of interoperable Internet/intranet added-value services.
Stelios Orphanoudakis   +4 more
core  

Home - About - Disclaimer - Privacy