Results 61 to 70 of about 3,039,823 (303)
Molecular Oncology, EarlyView.Glioma cells mainly express the endothelin receptor EDNRB, while EDNRA is restricted to a perivascular tumor subpopulation. Endothelin signaling reduces glioma cell proliferation while promoting migration and a proneural‐to‐mesenchymal transition associated with poor prognosis. This pathway activates Ca2+, K+, ERK, and STAT3 signalings and is regulated
Donovan Pineau +36 more
wiley +1 more source
Natural Hazards ResearchThe country wide lockdown implemented during 27th April to 14th June 2021 in order to prevent the spread of COVID-19 during the second wave in India. Effect of the restricted lockdown resulted in improved air quality.
Iranna Gogeri, K.C. Gouda, S.T. Aruna
doaj +1 more source
From normative towards positive epistemology: Problem of scientific fact [PDF]
Sociološki Pregled, 2009 In this article author provides a sketch of a twist from normative towards descriptive epistemology as a result of transformation of contemporary philosophy during the main occurrence known as Linguistic Turn.
Brdar Milan
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Transitivity for height versus speed: To what extent do the under-7s really have a transitive capacity? [PDF]
, 2011 This is the author's accepted manuscript. The final published article is available from the link below. Copyright @ 2011 Psychology Press.Transitive inference underpins many human reasoning competencies.
Hadfield, L, Robertson, S, Wright, BC
core +1 more source
Molecular Oncology, EarlyView.Loss of the miR‐214/199a cluster is associated with recurrence in ovarian cancer. Engineered small extracellular vesicles (m214‐sEVs) elevate miR‐214‐3p/miR‐199a‐5p in tumor cells, suppress β‐catenin, TLR4, and YKT6 signaling, reprogram tumor‐derived sEV cargo, reduce chemoresistance and migration, and enhance carboplatin efficacy and survival in ...
Weida Wang +12 more
wiley +1 more source
Surface reheating as a new paradigm
, 2002 In this talk we briefly review the standard idea of reheating and then present a new paradigm of reheating the Universe through surface evaporation.Comment: 4 pages, uses specific style file, talk given at string-phenomenology-02 ...
Enqvist, Kari +2 more
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Molecular Oncology, EarlyView.Keratin 19 (KRT19) is overexpressed in high‐grade serous ovarian cancer with high levels of Kallikrein‐related peptidases (KLK) 4–7 and is associated with poor survival. In vivo analyses demonstrate that elevated KRT19 increases peritoneal tumour burden.
Sophia Bielesch +13 more
wiley +1 more source
E2A selectively regulates TGF‐β–induced apoptosis in KRAS‐mutant non‐small cell lung cancer
Molecular Oncology, EarlyView.Ability to induce apoptosis by TGF‐β is frequently lost in advanced lung adenocarcinoma despite intact TGF‐β signaling. We identify E2A as a mutant KRAS–dependent mediator of resistance to TGF‐β–induced apoptosis. TGF‐β induces E2A via SMAD3 in mutant KRAS cells, and E2A silencing restores apoptosis and enhances radiation response in cell lines ...
Sergei Chuikov +3 more
wiley +1 more source
Fear information and social phobic beliefs in children: a prospective paradigm and preliminary results [PDF]
, 2002 This paper presents a first attempt to develop a prospective paradigm to test Rachman’s (Behav. Res. Ther. 15 (1977) 375) theory of fear acquisition for social fears. Following the prospective paradigm for animal fears developed by Field et al.
A.P Field +20 more
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Hijacking emergency granulopoiesis: Neutrophil ontogeny and reprogramming in cancer
Molecular Oncology, EarlyView.Neutrophils are highly plastic innate immune cells; their functions in cancer extend beyond the tumour microenvironment. This Review summarises current understanding of neutrophil maturation and heterogeneity and highlights tumour‐induced granulopoiesis as a systemic programme that expands immature, immunosuppressive neutrophils via tumour‐derived ...
Gabriela Marinescu, Yi Feng
wiley +1 more source