Results 41 to 50 of about 1,510,983 (309)

Microbiome‐blood–brain barrier interactions in aging — mechanisms and therapeutic potential

open access: yesFEBS Letters, EarlyView.
Aging reshapes the gut microbiome (↓SCFA‐producing commensals; ↑pro‐inflammatory outputs), shifting circulating metabolites (↓SCFAs; ↑LPS, ↑TMAO, ↑PAA) that act at the BBB to increase nonspecific transcytosis, alter transport, and promote astrocyte reactivity, heightening brain vulnerability.
Daniel Cuervo‐Zanatta   +3 more
wiley   +1 more source

A review on the extreme rainfall studies in India

open access: yesNatural Hazards Research
Climate vulnerability in the Indian region becomes a major concern due to the frequent hydro-meteorological extreme events throughout the year. The number of extreme rainfall events (ERE) associated with monsoon, thunderstorms and short-spanned local ...
Payoshni Samantray   +1 more
doaj   +1 more source

Alternatives for sustained disaster risk reduction: A re-assessment

open access: yesJàmbá, 2023
Alternatives for sustained disaster risk reduction’ was published in 2010 by Francophone and Anglophone researchers as a critique on the way disasters were studied and disaster risk reduction handled in the Francophone sphere.
Loic Le De   +8 more
doaj   +1 more source

Structure‐forward targeting of claudins with synthetic binders

open access: yesFEBS Letters, EarlyView.
Claudins form the paracellular barriers between epithelial and endothelial tissues at tight junctions and are targets for molecular binders with the goal of modulating barrier permeability. Claudin‐binding molecules are relevant in drug delivery or in altering claudin interactions with disease‐causing proteins.
Alex J. Vecchio
wiley   +1 more source

Contemporary patterns of transatlantic trade cooperation in a post-Brexit European Union (dis)order [PDF]

open access: yesCES Working Papers, 2020
This paper aims to examine the debate surrounding negotiations of the Transatlantic Trade and Investment Partnership (TTIP). The EU and US began negotiations for this comprehensive commercial agreement in July 2013 and have still not reached consensus ...
Iulia-Anamaria GHIDIU
doaj   +2 more sources

SOCIAL APPROACH OF THE RELATIONSHIP CONCEPT IN INTERNATIONAL RELATIONS

open access: yesStudia Universitatis Babeş-Bolyai. Studia Europaea, 2017
In this paper, we will address to deficits of the study of relationship construction in IR by approaching the meaning of the concept in network structures.
Salanțiu TUDOR
doaj   +1 more source

Observed and model‐simulated thermodynamic processes associated with urban heavy rainfall events over Bangalore, India

open access: yesMeteorological Applications, 2020
A total of 32 rainfall events spanning the period from 2012 to 2014 over the urban Indian city of Bangalore were simulated using the Weather Research and Forecast (WRF) model.
P. Ajilesh   +3 more
doaj   +1 more source

Trans-Paradigm of Ex-Khilafah Ideologists; Paradigm Changes Analysis of Ex-Khilafah Ideologists in Tapal Kuda

open access: yesAt-turas: Jurnal Studi Keislaman, 2023
This research is based on the gap between the theory of religious conflict and the reality of the religious transition paradigm currently. Media issues have warmed up again lately with some news about the policy of disbanding radical mass organizations ...
Rif'an Humaidi   +2 more
doaj   +1 more source

Engineering peptides into antibodies—opportunities and strategies for therapeutic innovation

open access: yesFEBS Letters, EarlyView.
Peptides and antibodies occupy complementary therapeutic niches. Peptides recognize difficult targets in a compact format, while antibodies add specificity, long half‐life, and effector functions. This review examines strategies that merge both modalities—peptide grafting into loops, terminal and Fc fusions, and bioconjugation—highlighting how ...
Jinling Wang   +2 more
wiley   +1 more source

ТЕУРГІЧНЕ БОГОБОРСТВО ЯК АЛГОРИТМ «ДО-БІБЛІЙНОЇ» СВІТОГЛЯДНОЇ САМОСВІДОМОСТІ [PDF]

open access: yes, 2015
Існує певна невизначеність у питанні про чинники, які впливали на формування біблійної картини світу. Біблія виникла у контексті язичницьких релігій Стародавнього Сходу і виступила в ролі протофілософії, оскільки ідея Єдиного Бога породжена раціонально ...
Чікарькова, М. Ю.
core   +1 more source

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