Results 81 to 90 of about 3,159,185 (350)

MiR‐513a promotes human erythroid differentiation by modulating c‐Jun

open access: yesFEBS Open Bio, EarlyView.
During early human erythropoiesis, miR‐513a promoted erythroid differentiation in primary human CD34+ hematopoietic stem‐progenitor cells and human TF‐1 erythroleukemic cells by indirectly decreasing c‐Jun and phospho‐c‐Jun expression, which are associated with increased GATA1 expression.
MinJung Kim   +11 more
wiley   +1 more source

Discrete Unilateral Constrained Extended Kalman Filter in an Embedded System

open access: yesSensors
Since its publication in the 1960s, the Kalman Filter (KF) has been a powerful tool in optimal state estimation. However, the KF and most of its variants have mainly focused on the state estimation of smooth systems.
Leonardo Herrera   +1 more
doaj   +1 more source

Model Extraction Warning in MLaaS Paradigm

open access: yes, 2017
Cloud vendors are increasingly offering machine learning services as part of their platform and services portfolios. These services enable the deployment of machine learning models on the cloud that are offered on a pay-per-query basis to application ...
Carlini N.   +4 more
core   +1 more source

Natural Products as Geroprotective Modulators in Diabetic Nephropathy: A Mechanistic Framework Integrating Aging Hallmarks and the AMPK–SIRT1–Nrf2 Axis

open access: yesAging and Cancer, EarlyView.
Natural products target the aging kidney in diabetic nephropathy by restoring the AMPK–SIRT1–Nrf2 axis, reducing oxidative stress, inflammation, fibrosis, and cellular senescence while enhancing mitochondrial biogenesis and antioxidant defenses.
Sherif Hamidu   +8 more
wiley   +1 more source

Scalable Learning Paradigms for Data-Driven Wireless Communication [PDF]

open access: green, 2020
Yue Xu   +5 more
openalex   +1 more source

Knowledge Management: The Paradigm of Complexity [PDF]

open access: yes, 2007
Knowledge Management encounters difficulties when it aims to tackle the complexity of the innovating firms structure. Indeed, it has to enhance emergent strategies while preserving the executives goals. This may be obtained through continuous training so
Benchimol, Guy
core  

Deep Learning–Assisted Differentiation of Four Peripheral Neuropathies Using Corneal Confocal Microscopy

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Peripheral neuropathies contribute to patient disability but may be diagnosed late or missed altogether due to late referral, limitation of current diagnostic methods and lack of specialized testing facilities. To address this clinical gap, we developed NeuropathAI, an interpretable deep learning–based multiclass classification ...
Chaima Ben Rabah   +7 more
wiley   +1 more source

Paradigm Shift [PDF]

open access: yes
This paper analyses the consequences of young researchers' scientifc choice on the dynamics of sciences. We develop a simple two state mean field game model to analyze the competition between two paradigms based on Kuhn's theory of scientifc revolutions.
Damien Besancenot, Habib Dogguy
core  

Will Memantine Exacerbate Seizures in People With Epilepsy? A Prospective Cohort Study

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective To evaluate whether add‐on memantine would exacerbate seizures in people with epilepsy. Methods This was a prospective cohort study. People with epilepsy diagnosed with cognitive impairment were consecutively invited. Those who agreed were followed up for at least 24 weeks.
Peiyu Wang   +7 more
wiley   +1 more source

Valuing ecosystem services: A new paradigm shift [PDF]

open access: yes, 2006
The ways in which economists value natural resources has been, and continues to be, a constantly evolving process. At first, only transactions that took place in the marketplace were considered.
Kaval, Pamela
core   +1 more source

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