Results 21 to 30 of about 575 (262)
PARADIGMES THÉÂTRAUX DANS MADAME BOVARY [PDF]
Studii si Cercetari Filologice: Seria Limbi Romanice, 2010 La perspective théâtrale du personnage dans Madame Bovary a son origine dans une barrière se trouvant entre celui-ci et le monde environnant, par laquelle sont mises en évidence des relations médiées.
Razvan VENTURA
doaj
Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system
FEBS Letters, EarlyView.Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley +1 more source
FEBS Letters, EarlyView.Plasma membranes contain dynamic nanoscale domains that organize lipids and receptors. Because viruses operate at similar scales, this architecture shapes early infection steps, including attachment, receptor engagement, and entry. Using influenza A virus and HIV‐1 as examples, we highlight how receptor nanoclusters, multivalent glycan interactions ...
Jan Schlegel, Christian Sieben
wiley +1 more source
La representació occidental de la Xina moderna: orientalisme, culturalisme i crítica historiogràfica
Digithum, 2008 La percepció que des d'Occident s'ha tingut de la Xina com a ens històric ha evolucionat al llarg dels segles. La Xina va passar de ser un país de prodigis i meravelles en el món medieval i una cultura refinada i erudita al començament de la modernitat ...
David Martínez-Robles
doaj
Revue Francophone de Recherche en Ergothérapie, 2022 À partir du cas de figure de l’application d’un algorithme clinique en ergothérapie (Algo) dans le réseau de la santé et des services sociaux du Québec, ce texte vulgarise les paradigmes et les concepts subjacents au processus d’application des ...
Mélanie Ruest, Manon Guay
doaj +1 more source
Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment
Molecular Oncology, EarlyView.This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley +1 more source
Molecular Oncology, EarlyView.Pre‐analytical handling critically determines liquid biopsy performance. This study defines practical best‐practice conditions for cell‐free DNA (cfDNA) and extracellular vesicle–derived DNA (evDNA), showing how processing time, storage conditions, tube type, and plasma input volume affect DNA integrity and mutation detection.
Jonas Dohmen +11 more
wiley +1 more source
Molecular Oncology, EarlyView.Glioma cells mainly express the endothelin receptor EDNRB, while EDNRA is restricted to a perivascular tumor subpopulation. Endothelin signaling reduces glioma cell proliferation while promoting migration and a proneural‐to‐mesenchymal transition associated with poor prognosis. This pathway activates Ca2+, K+, ERK, and STAT3 signalings and is regulated
Donovan Pineau +36 more
wiley +1 more source
Introduction. Les paradigmes de la justice [PDF]
Meta: Research in Hermeneutics, Phenomenology and Practical Philosophy, 2009 Theories of justice are marred by a permanent state of conflict because they express prejudices whose source lies in the lifeworld. One may regard these theories as interpretations of the concept of justice. Assuming a strong meaning of “theory,” one can
Cornelui Bîlbă
doaj
Entre dois paradigmas: combate à seca e convivência com o semi-árido
Sociedade e Estado, 2003 Grande parte dos diagnósticos e proposições sobre o semi-árido brasileiro tem como referência imagens historicamente construídas sobre um espaço-problema, terra das secas e da miséria.
Roberto Marinho Alves da Silva
doaj +1 more source