Results 31 to 40 of about 17,142 (229)

Forecasting the Dialysis Burden in Japan: Validation‐Based Projections of Prevalence and Incidence Through 2050

open access: yesTherapeutic Apheresis and Dialysis, EarlyView.
ABSTRACT Background Japan has one of the highest dialysis prevalence rates worldwide and a shrinking, aging population. Whether dialysis burden has entered a sustained post‐peak phase or whether recent declines partly reflect pandemic‐related disruptions remains uncertain.
Hatice Şahin   +2 more
wiley   +1 more source

Pour une modélisation surfaciste de la flexion. Le cas de la conjugaison du français

open access: yesSHS Web of Conferences, 2016
Les descriptions de la morphologie flexionnelle des langues sont naturellement basées sur l’observation détaillée de l’ensemble des propriétés connues des systèmes en question mais quelle part de ces connaissances est accessible aux locuteurs ?
Boyé Gilles
doaj   +1 more source

Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system

open access: yesFEBS Letters, EarlyView.
Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley   +1 more source

Organizing the interface—Plasma membrane architecture and receptor dynamics in virus‐cell interactions

open access: yesFEBS Letters, EarlyView.
Plasma membranes contain dynamic nanoscale domains that organize lipids and receptors. Because viruses operate at similar scales, this architecture shapes early infection steps, including attachment, receptor engagement, and entry. Using influenza A virus and HIV‐1 as examples, we highlight how receptor nanoclusters, multivalent glycan interactions ...
Jan Schlegel, Christian Sieben
wiley   +1 more source

Etat des lieux de la canalisation des recherches en entrepreneuriat en République Démocratique du Congo via les paradigmes [PDF]

open access: yesMouvements et Enjeux Sociaux, 2023
L’entrepreneuriat est un des sujets qui polarise l’attention des gens de tout bord : politiciens, enseignants, chômeurs, employés, etc. s’y intéressent.
Célestin MUTOMBO KAZADI   +2 more
doaj  

From mice to humans—divergent strategies for intestinal homeostasis and regeneration

open access: yesFEBS Letters, EarlyView.
Recent advances such as organoid genome editing, xenotransplantation, imaging, and whole‐genome sequencing have enabled direct studies of human intestinal stem cells (ISCs). These studies reveal species‐specific features, including slower ISC proliferation, distinct injury responses, slower somatic mutation accumulation in humans, and an inverse ...
Keiko Ishikawa   +2 more
wiley   +1 more source

Modelling stem cell differentiation related processes—A practical overview for biologists

open access: yesFEBS Letters, EarlyView.
Stem cell differentiation is complex and difficult to control experimentally. This review introduces suitable computational modelling approaches that can support stem cell research, from mechanistic ODE and abstract models to multiscale and deep learning methods.
Ricco Zeegelaar   +4 more
wiley   +1 more source

Écriture et plurilinguisme dans _Traversée de la mangrove_

open access: yesVoix Plurielles, 2011
L’hétérolinguisme dans le texte littéraire et le fait plurilinguistique sont, non seulement des caractéristiques fondamentales des écritures francophones, mais constituent des paradigmes importants pour la description des effets de langue qui fondent ces
Kimberley Bruno
doaj   +3 more sources

PARADIGMES THÉÂTRAUX DANS MADAME BOVARY [PDF]

open access: yesStudii si Cercetari Filologice: Seria Limbi Romanice, 2010
La perspective théâtrale du personnage dans Madame Bovary a son origine dans une barrière se trouvant entre celui-ci et le monde environnant, par laquelle sont mises en évidence des relations médiées.
Razvan VENTURA
doaj  

Microbiome‐blood–brain barrier interactions in aging — mechanisms and therapeutic potential

open access: yesFEBS Letters, EarlyView.
Aging reshapes the gut microbiome (↓SCFA‐producing commensals; ↑pro‐inflammatory outputs), shifting circulating metabolites (↓SCFAs; ↑LPS, ↑TMAO, ↑PAA) that act at the BBB to increase nonspecific transcytosis, alter transport, and promote astrocyte reactivity, heightening brain vulnerability.
Daniel Cuervo‐Zanatta   +3 more
wiley   +1 more source

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