Results 21 to 30 of about 213,495 (269)

World on Data Perspective

open access: yesWorld, 2022
It is not simple to consider the world from only one side, but analyzing all sides can cloud comprehension without reaching deep insight found at the core.
Mahyuddin K. M. Nasution
doaj   +1 more source

Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system

open access: yesFEBS Letters, EarlyView.
Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley   +1 more source

PERCEIVED SERVICE QUALITY IN CONTEXT OF RURAL AND URBAN BANKS IN PAKISTAN [PDF]

open access: yesParadigms, 2016
Perceived service quality is very important concept in banking sector. It is therefore necessary to acknowledge the perception of customers from different areas-as they are becoming more critical and demanding.
MUHAMMAD FAROOQ SHABBIR   +4 more
doaj  

Aggressive prostate cancer is associated with pericyte dysfunction

open access: yesMolecular Oncology, EarlyView.
Tumor‐produced TGF‐β drives pericyte dysfunction in prostate cancer. This dysfunction is characterized by downregulation of some canonical pericyte markers (i.e., DES, CSPG4, and ACTA2) while maintaining the expression of others (i.e., PDGFRB, NOTCH3, and RGS5).
Anabel Martinez‐Romero   +11 more
wiley   +1 more source

The Long Walk to Leadership: Are Women their Own Worst Enemies? [PDF]

open access: yesParadigms, 2015
This study traces subordinate women’s perceptions of the root causes of the rift and polarization between women in subordinate positions and women in super-ordinate positions and how this impacts female leadership emergence.
Samson Mutsagondo
doaj  

Dual targeting of RET and SRC synergizes in RET fusion‐positive cancer cells

open access: yesMolecular Oncology, EarlyView.
Despite the strong activity of selective RET tyrosine kinase inhibitors (TKIs), resistance of RET fusion‐positive (RET+) lung cancer and thyroid cancer frequently occurs and is mainly driven by RET‐independent bypass mechanisms. Son et al. show that SRC TKIs significantly inhibit PAK and AKT survival signaling and enhance the efficacy of RET TKIs in ...
Juhyeon Son   +13 more
wiley   +1 more source

Factors Affecting Organizational Performance [PDF]

open access: yesParadigms, 2011
There is an accumulated body of literature on the diffusion of a variety of relatively new strategic management tools in organizations. However, there is scant research on the level of association between the adoption of these techniques and ...
Davood Askarany
doaj  

Perspectives in educating molecular pathologists on liquid biopsy: Toward integrative, equitable, and decentralized precision oncology

open access: yesMolecular Oncology, EarlyView.
Liquid biopsy enables minimally invasive, real‐time molecular profiling through analysis of circulating biomarkers in biological fluids. This Perspective highlights the importance of training pathologists through integrative educational programs, such as the European Masters in Molecular Pathology, to ensure effective and equitable implementation of ...
Marius Ilié   +13 more
wiley   +1 more source

Problematic Internet Use: Deficient Self-Regulation Or Pathology? [PDF]

open access: yesParadigms, 2012
Increasing research on problematic internet use (PIU) makes it necessary to distinguish between the generalized use of internet and its specific applications. This study explores the relationships amongst psychosocial vulnerabilities, specific PIU (SPIU),
Shumaila Yousaf Zai   +2 more
doaj  

MENUJU SOSIOLOGI BERAGAMA: Paradigma Keilmuan dan Tantangan Kontemporer Kajian Sosiologi Agama di Indonesia

open access: yesJurnal Sosiologi Agama, 2021
Artikel ini membahas paradigma, perkembangan, serta tantangan kajian sosiologi agama di Indonesia. Kajian Sosiologi Agama di Indonesia yang telah tumbuh di lingkungan Perguruan Tinggi Agama Islam Negeri (PTKIN) di Indonesia, secara epistemologis adalah ...
Moh Soehadha
doaj   +1 more source

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