Results 41 to 50 of about 379,970 (318)
α‐Synuclein aggregation landscape from phase separation to neurotoxic intermediates
FEBS Letters, EarlyView.Alpha‐synuclein aggregation in Parkinson's disease involves a complex landscape of transient intermediates, including oligomers, fibrils and liquid–liquid phase separation (LLPS). A view is emerging in which LLPS maturation into solid‐like condensates may contribute to the formation of neurotoxic species.
Silvia Arino +2 more
wiley +1 more source
Factors Affecting Organizational Performance [PDF]
Paradigms, 2011 There is an accumulated body of literature on the diffusion of a variety of relatively new strategic management tools in organizations. However, there is scant research on the level of association between the adoption of these techniques and ...
Davood Askarany
doaj
Paradigms as heuristics: a review of the philosophies underpinning economic studies in entrepreneurship [PDF]
, 2003 This paper addresses contemporary debates about paradigms in organization studies and uses Burrell and Morgan's (1979) framework to undertake an analysis of the metatheories underlying economic theories in entrepreneurship.
Pittaway, L A
core
Modelling stem cell differentiation related processes—A practical overview for biologists
FEBS Letters, EarlyView.Stem cell differentiation is complex and difficult to control experimentally. This review introduces suitable computational modelling approaches that can support stem cell research, from mechanistic ODE and abstract models to multiscale and deep learning methods.
Ricco Zeegelaar +4 more
wiley +1 more source
Problematic Internet Use: Deficient Self-Regulation Or Pathology? [PDF]
Paradigms, 2012 Increasing research on problematic internet use (PIU) makes it necessary to distinguish between the generalized use of internet and its specific applications. This study explores the relationships amongst psychosocial vulnerabilities, specific PIU (SPIU),
Shumaila Yousaf Zai +2 more
doaj
Paradigms for abstracting systems [PDF]
, 1999 The ever-growing amount of documents (electronic or other)has increased the value of abstracts, and abstracting systemsand services, as instruments for concentrating and supplying relevant information.
Pinto, María, Gálvez, Carmen
core
Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment
Molecular Oncology, EarlyView.This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley +1 more source
A STUDY ON THE ISSUES OF EMPLOYMENT CONTRACTS AND PRACTICES OF EMPLOYMENT CONTRACTS IN UAE [PDF]
Paradigms, 2016 People who belongs to underdeveloped and developing countries, focus on getting employment in different developed countries. In the recent past years the number of people working in different countries has increased dramatically. In Pakistan it’s a trend
SYED HUSSAIN HAIDER +3 more
doaj
Molecular Oncology, EarlyView.Pre‐analytical handling critically determines liquid biopsy performance. This study defines practical best‐practice conditions for cell‐free DNA (cfDNA) and extracellular vesicle–derived DNA (evDNA), showing how processing time, storage conditions, tube type, and plasma input volume affect DNA integrity and mutation detection.
Jonas Dohmen +11 more
wiley +1 more source
Determinants Of Equity Prices In The Stock Market [PDF]
Paradigms, 2010 This study examines the effect of market variables on the movement stock prices in Pakistan. Asset pricing is considered as efficient if the asset prices reflect all available market information.
Muhammad Usman Javaid
doaj