Results 51 to 60 of about 1,063,823 (303)

A STUDY ON THE ISSUES OF EMPLOYMENT CONTRACTS AND PRACTICES OF EMPLOYMENT CONTRACTS IN UAE [PDF]

open access: yesParadigms, 2016
People who belongs to underdeveloped and developing countries, focus on getting employment in different developed countries. In the recent past years the number of people working in different countries has increased dramatically. In Pakistan it’s a trend
SYED HUSSAIN HAIDER   +3 more
doaj  

A paradigmatic map of professional education research [PDF]

open access: yes, 2011
This article maps out research in professional education with reference to a threefold typology of paradigms i.e. the positivist, interpretivist and critical paradigms. The rationale for such an endeavour is fourfold.
Humphrey, Caroline
core   +2 more sources

EDNRB‐dependent endothelin signaling reduces proliferation and promotes proneural‐to‐mesenchymal transition in gliomas

open access: yesMolecular Oncology, EarlyView.
Glioma cells mainly express the endothelin receptor EDNRB, while EDNRA is restricted to a perivascular tumor subpopulation. Endothelin signaling reduces glioma cell proliferation while promoting migration and a proneural‐to‐mesenchymal transition associated with poor prognosis. This pathway activates Ca2+, K+, ERK, and STAT3 signalings and is regulated
Donovan Pineau   +36 more
wiley   +1 more source

Determinants Of Equity Prices In The Stock Market [PDF]

open access: yesParadigms, 2010
This study examines the effect of market variables on the movement stock prices in Pakistan. Asset pricing is considered as efficient if the asset prices reflect all available market information.
Muhammad Usman Javaid
doaj  

Engineered extracellular vesicles enriched with the miR‐214/199a cluster enhance the efficacy of chemotherapy in ovarian cancer

open access: yesMolecular Oncology, EarlyView.
Loss of the miR‐214/199a cluster is associated with recurrence in ovarian cancer. Engineered small extracellular vesicles (m214‐sEVs) elevate miR‐214‐3p/miR‐199a‐5p in tumor cells, suppress β‐catenin, TLR4, and YKT6 signaling, reprogram tumor‐derived sEV cargo, reduce chemoresistance and migration, and enhance carboplatin efficacy and survival in ...
Weida Wang   +12 more
wiley   +1 more source

A Comparative Study of CAPM and Seven Factors Risk Adjusted Return Model [PDF]

open access: yesParadigms, 2014
This study is a comparison and contrast of the predictive powers of two asset pricing models: CAPM and seven factor risk-return adjusted model, to explain the cross section of stock rate of returns in the financial sector listed at Karachi Stock Exchange
Madiha Riaz Bhatti, Abu Bakar Mirza
doaj  

Keratin 19 as a prognostic marker and contributing factor of metastasis and chemoresistance in high‐grade serous ovarian cancer

open access: yesMolecular Oncology, EarlyView.
Keratin 19 (KRT19) is overexpressed in high‐grade serous ovarian cancer with high levels of Kallikrein‐related peptidases (KLK) 4–7 and is associated with poor survival. In vivo analyses demonstrate that elevated KRT19 increases peritoneal tumour burden.
Sophia Bielesch   +13 more
wiley   +1 more source

THE EFFECT OF DEVOTEE-BASED BRAND EQUITY ON RELIGIOUS EVENTS [PDF]

open access: yesParadigms, 2016
The objective of this research is to apply DBBE model to discover the constructs to measure the religious event as a business brand on the bases of devotees’ perception.
MUHAMMAD JAWAD IQBAL   +3 more
doaj  

E2A selectively regulates TGF‐β–induced apoptosis in KRAS‐mutant non‐small cell lung cancer

open access: yesMolecular Oncology, EarlyView.
Ability to induce apoptosis by TGF‐β is frequently lost in advanced lung adenocarcinoma despite intact TGF‐β signaling. We identify E2A as a mutant KRAS–dependent mediator of resistance to TGF‐β–induced apoptosis. TGF‐β induces E2A via SMAD3 in mutant KRAS cells, and E2A silencing restores apoptosis and enhances radiation response in cell lines ...
Sergei Chuikov   +3 more
wiley   +1 more source

Perception Of Trader Towards International Trade: A Diagnostic Study [PDF]

open access: yesParadigms, 2010
In this article the authors have identified the significant factors that influence international trade in the light of traders. Foreign exchange transaction may prove to be helpful in managing currency risk which is associated with import and export of ...
Muzaffar Asad
doaj  

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