Results 61 to 70 of about 478,239 (309)
Molecular Oncology, EarlyView.We identify USP29 as the only DUB mirroring CA9 expression, a marker of hypoxia and HIF pathway activation associated with PCA aggressiveness. USP29 stabilizes HIF‐1α and HIF‐2α via a noncanonical mechanism that is independent of PHD/pVHL activity yet relies on proteasomal regulation, establishing USP29 as a previously unrecognized regulator of hypoxic
Amelie S Schober +16 more
wiley +1 more source
P168: Nutritional markers of histamine intolerance in Ehlers-Danlos syndromes
Genetics in Medicine Open, 2023 Jessica Pizano +5 more
doaj +1 more source
Does Comparative Advantage Affect Economic Growth: A Case of Pakistan with Asian, OECD and Latin American Economies 1982-2011 [PDF]
Paradigms, 2015 Present study endeavours to assess the comparative advantage of Pakistan’s exports to selected regional economies around the world namely Asian, OECD, and Latin American economies.
Ijaz Hussain Bokhari +2 more
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Research in Integrated Care: The Need for More Emergent, People-Centred Approaches
International Journal of Integrated Care, 2020 The International Foundation for Integrated Care (IFIC) recently celebrated its 20th International Conference (ICIC20) through a virtual event that brought together patients and carers, academics, care professionals, NGOs, policy-makers and industry ...
Wilma van der Vlegel-Brouwer +4 more
doaj +1 more source
Molecular Oncology, EarlyView.Single‐cell DNA methylation (scDNAme) profiling maps epimutational clonal evolution, revealing mechanisms of malignancy and therapeutic resistance across diverse cancer types. By providing a high‐resolution landscape of intratumoral heterogeneity, these technologies empower precise patient stratification, guide the development of enhanced ...
Ik Soo Kim
wiley +1 more source
Transformational Leadership Style and Organization Commitment [PDF]
Paradigms, 2015 This research is about transformational leadership style on organization commitment in Punjab. We collected data through questionnaire from education and banking sector of Punjab.
Muhammad Ramzan Mehar, , and +3 more
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ADP‐ribosylation: An emerging regulator of the epigenome
Molecular Oncology, EarlyView.ADP‐ribosylation has emerged as a dynamic epigenetic signaling mechanism that modifies histones and chromatin‐associated proteins. Through coordinated PARylation and MARylation, it integrates with other histone modifications to regulate chromatin structure, transcription factor activity, and gene expression, influencing genome function and disease ...
Cristel V. Camacho +2 more
wiley +1 more source
Investigation Of Export-Led Growth And Growth-Led Export Hypotheses: A Study On Pakistan Exports To USA, UAE and UK [PDF]
Paradigms, 2011 his article is about investigation of export-led growth and growth-led export hypotheses in case of Pakistan exports to top three exports partners namely: USA, UAE and UK. Time series data over the period of 1975 to 2012 has been used.
Muhammad Azhar Ikram Ahmad +2 more
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Molecular Oncology, EarlyView.Arginine methylation can be viewed as a persistence‐prone post‐translational modification regulated by a network of PRMTs. Competitive and compensatory interactions among PRMTs can redistribute methylation across substrate pools shaped by sequence, structural, spatial, and environmental layers, reinforcing RNA‐processing, chromatin, and signaling ...
So Hyun Kwon, Ji Min Lee
wiley +1 more source
KEY FACTORS INFLUENCING PURCHASE INTENTIONS TOWARDS AUTOMOBILES IN PAKISTAN [PDF]
Paradigms, 2016 In this paper the authors identify and investigate the key factors which influence intentions to purchase passenger cars among consumers in Pakistan. A questionnaire was developed to check the significance of these key variables identified from previous ...
SYED NAVEED ALTAF, NOOR AZMI HASHIM
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