Weakening the nuclear envelope: Lamin B receptor in melanoma metastasis
LBR‐driven nuclear fragility supports melanoma invasion. A: Melanocyte presents low LBR (Lamin B Receptor) levels, maintaining nuclear integrity and lamina‐chromatin tethering. B: During malignant progression, upregulation of LBR clusters at the INM (Inner Nuclear Membrane) during confined migration causes local lamina weakening and cholesterol ...
Francesca Lorenzini +1 more
wiley +1 more source
KEY FACTORS INFLUENCING PURCHASE INTENTIONS TOWARDS AUTOMOBILES IN PAKISTAN [PDF]
In this paper the authors identify and investigate the key factors which influence intentions to purchase passenger cars among consumers in Pakistan. A questionnaire was developed to check the significance of these key variables identified from previous ...
SYED NAVEED ALTAF, NOOR AZMI HASHIM
doaj
Towards Linking Four Emerging Paradigms in Economic Theory—Regulationist, Institutionalist, Post-modernist, and Post-development [PDF]
This paper is an epistemological attempt to synthesise four emerging paradigms in economic theory. These paradigms are the regulationist, the institutionalist, the post-modernist, and the post-development. Arguably, these are paradigms rather than models
Moazam Mahmood, Durr-E-Nayab
core
MiR‐513a promotes human erythroid differentiation by modulating c‐Jun
During early human erythropoiesis, miR‐513a promoted erythroid differentiation in primary human CD34+ hematopoietic stem‐progenitor cells and human TF‐1 erythroleukemic cells by indirectly decreasing c‐Jun and phospho‐c‐Jun expression, which are associated with increased GATA1 expression.
MinJung Kim +11 more
wiley +1 more source
ELECTRONIC BANKING AS ANS COMPETITIVE EDGE FOR COMMERCIAL BANKS OF PAKISTAN: ROE MODEL [PDF]
The impact of electronic banking on the profitability of commercial banks has been measured by developing the integrated model based on Return on Equity for the period of 2002 to 2012.
Sundas Rauf +1 more
doaj
Rise and development of Slavic accentual paradigms
It appears that the complexity of Slavic historical accentology is prohibitive for most non-specialists in the field. It may therefore be useful to approach the subject from a number of different angles in order to render it more accessible to a wider ...
Kortlandt, Frederik H. H.
core
Characterising marketing paradigms for sustainable marketing management
Purpose Economic theories shape marketing paradigms, and these, in turn, can either aid or inhibit marketing managers\u27 abilities to contribute to the goal of sustainability - long-term wellbeing for all. The marketing paradigm drawn on is therefore of
Hurth, V +5 more
core +1 more source
Understanding commissioned research and scholarship in education: do paradigms matter?
The place and challenges of identifying and working with paradigms in the context of commissioned research are addressed in this chapter. The characteristics of commissioned research activities are discussed and considered by drawing on Boyer's view of ...
Kay Livingston, Livingston, Kay
core +1 more source
YIPFα1A expression is regulated by multilayered molecular mechanisms
YIPFα1A, a five‐pass Golgi protein, is regulated at multiple layers. (1) Rare‐codon enrichment drives translation‐coupled mRNA decay. (2) A proximal 3′‐UTR element stabilizes mRNA. (3) A distal 3′‐UTR element included by alternate poly(A) site usage represses translation, which can be overridden by the proximal 3′‐UTR element.
Tokio Takaji +2 more
wiley +1 more source
Exchange Rate Instability and Sectoral Exports: Evidence from Pakistan [PDF]
Exports of a country is one of the main factors indicating economic health of a country and fluctuating exchange rates and relative price can significantly affect the level of exports and it is an alarming situation for a country when its exports are ...
Muhammad Haseeb, Muhammad Awais Iqbal
doaj

