Results 31 to 40 of about 1,042,979 (301)
Two Paradigms of Jurisdiction [PDF]
, 2006 Globalization causes convergence of legal orders. Or so it is argued. Law and economics scholars predict that legal orders will move towards the same efficient end state.
Michaels, Ralf
core +2 more sources
New Paradigms For Asteroid Formation
, 2015 Asteroids and meteorites provide key evidence on the formation of planetesimals in the Solar System. Asteroids are traditionally thought to form in a bottom-up process by coagulation within a population of initially km-scale planetesimals.
Cuzzi, Jeffrey N. +4 more
core +1 more source
The newfound relationship between extrachromosomal DNAs and excised signal circles
FEBS Letters, EarlyView.Extrachromosomal DNAs (ecDNAs) contribute to the progression of many human cancers. In addition, circular DNA by‐products of V(D)J recombination, excised signal circles (ESCs), have roles in cancer progression but have largely been overlooked. In this Review, we explore the roles of ecDNAs and ESCs in cancer development, and highlight why these ...
Dylan Casey, Zeqian Gao, Joan Boyes
wiley +1 more source
PERCEIVED SERVICE QUALITY IN CONTEXT OF RURAL AND URBAN BANKS IN PAKISTAN [PDF]
Paradigms, 2016 Perceived service quality is very important concept in banking sector. It is therefore necessary to acknowledge the perception of customers from different areas-as they are becoming more critical and demanding.
MUHAMMAD FAROOQ SHABBIR +4 more
doaj
FEBS Letters, EarlyView.We identified a systemic, progressive loss of protein S‐glutathionylation—detected by nonreducing western blotting—alongside dysregulation of glutathione‐cycle enzymes in both neuronal and peripheral tissues of Taiwanese SMA mice. These alterations were partially rescued by SMN antisense oligonucleotide therapy, revealing persistent redox imbalance as ...
Sofia Vrettou, Brunhilde Wirth
wiley +1 more source
The Long Walk to Leadership: Are Women their Own Worst Enemies? [PDF]
Paradigms, 2015 This study traces subordinate women’s perceptions of the root causes of the rift and polarization between women in subordinate positions and women in super-ordinate positions and how this impacts female leadership emergence.
Samson Mutsagondo
doaj
A synthetic benzoxazine dimer derivative targets c‐Myc to inhibit colorectal cancer progression
Molecular Oncology, EarlyView.Benzoxazine dimer derivatives bind to the bHLH‐LZ region of c‐Myc, disrupting c‐Myc/MAX complexes, which are evaluated from SAR analysis. This increases ubiquitination and reduces cellular c‐Myc. Impairing DNA repair mechanisms is shown through proteomic analysis.
Nicharat Sriratanasak +8 more
wiley +1 more source
Factors Affecting Organizational Performance [PDF]
Paradigms, 2011 There is an accumulated body of literature on the diffusion of a variety of relatively new strategic management tools in organizations. However, there is scant research on the level of association between the adoption of these techniques and ...
Davood Askarany
doaj
Aggressive prostate cancer is associated with pericyte dysfunction
Molecular Oncology, EarlyView.Tumor‐produced TGF‐β drives pericyte dysfunction in prostate cancer. This dysfunction is characterized by downregulation of some canonical pericyte markers (i.e., DES, CSPG4, and ACTA2) while maintaining the expression of others (i.e., PDGFRB, NOTCH3, and RGS5).
Anabel Martinez‐Romero +11 more
wiley +1 more source
Problematic Internet Use: Deficient Self-Regulation Or Pathology? [PDF]
Paradigms, 2012 Increasing research on problematic internet use (PIU) makes it necessary to distinguish between the generalized use of internet and its specific applications. This study explores the relationships amongst psychosocial vulnerabilities, specific PIU (SPIU),
Shumaila Yousaf Zai +2 more
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