Results 41 to 50 of about 448,850 (316)
A Nontransitive Theory of Truth over PA
Análisis Filosófico, 2021 David Ripley has argued extensively for a nontransitive theory of truth by dropping the rule of Cut in a sequent calculus setting in order to get around triviality caused by paradoxes such as the Liar.
Jonathan Dittrich
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Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment
Molecular Oncology, EarlyView.This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
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Наука. Культура. Общество, 2021 The article is devoted to the topical topic of the fourth industrial revolution, which every member of society is witnessing and participating in today. The author analyzes the process of forming a new social reality and notes its ambiguous nature.
Marina V. Kostolomova
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Molecular Oncology, EarlyView.We have established a humanized orthotopic patient‐derived xenograft (Hu‐oPDX) mouse model of high‐grade serous ovarian cancer (HGSOC) that recapitulates human tumor–immune interactions. Using combined anti‐PD‐L1/anti‐CD73 immunotherapy, we demonstrate the model's improved biological relevance and enhanced translational value for preclinical ...
Luka Tandaric +10 more
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HTS Teologiese Studies/Theological Studies, 2021 Pavel Alexandrovich Florensky is a towering figure of the 20th century. He is recognised among many significant thinkers of the world’s cultural and philosophical panorama of the previous century.
Johan Buitendag, Antonino Puglisi
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E2A selectively regulates TGF‐β–induced apoptosis in KRAS‐mutant non‐small cell lung cancer
Molecular Oncology, EarlyView.Ability to induce apoptosis by TGF‐β is frequently lost in advanced lung adenocarcinoma despite intact TGF‐β signaling. We identify E2A as a mutant KRAS–dependent mediator of resistance to TGF‐β–induced apoptosis. TGF‐β induces E2A via SMAD3 in mutant KRAS cells, and E2A silencing restores apoptosis and enhances radiation response in cell lines ...
Sergei Chuikov +3 more
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Molecular Oncology, EarlyView.Single‐cell multi‐omics reveals epigenetic heterogeneity across therapy‐adaptive tumor states, including quiescent/dormant, drug‐tolerant persister, and EMT‐like phenotypes. By linking regulatory features with state‐associated biomarkers, these approaches inform biomarker‐guided therapeutic strategies for evolving tumors.
Hee Jung Kim +3 more
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How do we know when the change is optimal?
Studies and Scientific Researches: Economics Edition, 2010 The analysis of the external environment must not be limited to the identification of the external factors, but must also take into account their importance. The real management capacity consists of finding out their signification, of identifying exactly
Lazar Latu, Roxana Latu
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Satire et transgression dans l’Eloge de la folie d’Erasme. La construction argumentative du sens de fou et de sage [PDF]
Studii de Lingvistica, 2022 Using an argumentative approach to semantics, the present article explores the construction of the meanings of fou and sage in Erasmus’ satire In Praise of Folly.
Roxana Voicu
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