Results 61 to 70 of about 448,850 (316)
Pharmacological inhibition of PERK in a DEN‐induced mouse model of liver cancer does not reduce tumor burden but alters cellular stress signaling. Despite blocking PERK activity, downstream stress responses, including CHOP expression, remain active, suggesting compensatory mechanisms within the unfolded protein response that may influence tumor ...
Ada Lerma‐Clavero +5 more
wiley +1 more source
A NEW CRITICAL READING OF GENIEVIVE NNAJI'S LIONHEART
Genevieve Nnaji’s Lionheart represents the creative and artistic qualities of Nollywood cinema. This study examines her film through the prism of New Criticism, focusing on the movie’s internal structure rather than its historical and cultural contexts.
Akeem SALAUDEEN
doaj +1 more source
The dual roles of CC and CXC chemokines in distinguishing active, latent, and subclinical tuberculosis were reviewed, along with an evaluation of their potential as diagnostic biomarkers and therapeutic targets to advance precision medicine in tuberculosis management. The graphical abstract was generated with AI assistance (Gemini 3.0).
Xuying Yin, Dangsheng Xiao, Jiezuan Yang
wiley +1 more source
Between the instrumental and the substantive: Paradoxes of a “common” project
The aim of the present study is to investigate the paradoxes concerning the construction of a social development project run by an NGO and a company in the recycling sector. The case study of the Southern Development Project is herein assessed.
Simone Alves Pacheco de Campos +2 more
doaj +1 more source
Cutaneous Melanoma Drives Metabolic Changes in the Aged Bone Marrow Immune Microenvironment
Melanoma, the deadliest form of skin cancer, increasingly affects older adults. Our study reveals that melanoma induces changes in iron and lipid levels in the bone marrow, impacting immune cell populations and increasing susceptibility to ferroptosis.
Alexis E. Carey +12 more
wiley +1 more source
Le « hors champ » du sexuel : les Anciens et les relations entre femmes
Recent studies regarding multiple sexualities in Greek and Roman Antiquity (or at least practices that contemporary scholars would classify as such) showed that categories used to describe sexualities were quite different from ours.
Sandra Boehringer
doaj +1 more source
Natural products target the aging kidney in diabetic nephropathy by restoring the AMPK–SIRT1–Nrf2 axis, reducing oxidative stress, inflammation, fibrosis, and cellular senescence while enhancing mitochondrial biogenesis and antioxidant defenses.
Sherif Hamidu +8 more
wiley +1 more source
Mothers and their offspring perceive the tritone paradox in closely similar ways
The tritone paradox is produced when two tones that are related by a half-octave (or tritone) are presented in succession, and the tones are so constructed that their pitch classes (C, C#, D; and so on) are clearly defined but their pitch heights are ...
Diana DEUTSCH
doaj
ABSTRACT Objective Super‐Refractory Status Epilepticus (SRSE) is a rare, life‐threatening neurological emergency with unclear etiology in many cases. Mitochondrial dysfunction, often due to disease‐causing genetic variants, is increasingly recognized as a cause, with each gene producing distinct pathophysiological mechanisms.
Pouria Mohammadi +2 more
wiley +1 more source
Kraut et al. (1998) reported negative effects of using the Internet on social involvement and psychological well-being among new Internet users in 1995–96. We called the effects a “paradox” because participants used the Internet heavily for communication,
R. Kraut +5 more
semanticscholar +1 more source

