Results 51 to 60 of about 1,405,451 (393)
Peroxidasin enables melanoma immune escape by inhibiting natural killer cell cytotoxicity
Molecular Oncology, EarlyView.Peroxidasin (PXDN) is secreted by melanoma cells and binds the NK cell receptor NKG2D, thereby suppressing NK cell activation and cytotoxicity. PXDN depletion restores NKG2D signaling and enables effective NK cell–mediated melanoma killing. These findings identify PXDN as a previously unrecognized immune evasion factor and a potential target to improve
Hsu‐Min Sung +17 more
wiley +1 more source
The Clock Paradox: Luise Lange's Discussion [PDF]
, 2018 In her articles on the clock paradox and the relativity of time Luise Lange (1891–1978) defends the theory of relativity against philosophical refutations, by showing that the apparent clock paradox is not a paradox, but merely conflicts with common ...
Reichenberger, Andrea
core
Statistical Science, 1999 zbMATH Open Web Interface contents unavailable due to conflicting licenses.
Harmer, G., Abbott, D.
openaire +4 more sources
Molecular Oncology, EarlyView.Etoposide induces DNA damage, activating p53‐dependent apoptosis via caspase‐3/7, which cleaves PARP1. Dammarenediol II enhances this apoptotic pathway by suppressing O‐GlcNAc transferase activity, further decreasing O‐GlcNAcylation. The reduction in O‐GlcNAc levels boosts p53‐driven apoptosis and influences the Akt/GSK3β/mTOR signaling pathway ...
Jaehoon Lee +8 more
wiley +1 more source
Is the materialization of architecture necessarily material? [PDF]
Arhitektura i Urbanizam, 2008 Architectural dematerialization process has started in the first half of the previous century, and has intensively developed at the beginning of this one.
Čarapić Ana
doaj
Performance Philosophy, 2017 Nietzsche’s Dionysus, admittedly, represents a direct provocation and an attack on the classical interpretation accepted since Winckelmann, an interpretation that elevates the Apollonian to its central point of focus; Nietzsche’s introduction of another ...
Dieter Mersch
doaj +1 more source
Solution of Supplee's submarine paradox through special and general relativity
, 2016 In 1989 Supplee described an apparent relativistic paradox on which a submarine seems to sink to observers at rest within the ocean, but it rather seems to float in the submarine proper frame. In this letter, we show that the paradox arises from a misuse
Vieira, R. S.
core +1 more source
Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment
Molecular Oncology, EarlyView.This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley +1 more source
Frontiers in Cardiovascular Medicine, 2022 BackgroundApolipoprotein B (ApoB) and low-density lipoprotein cholesterol (LDL-C) were identified targets for blood lipid management among coronary artery disease (CAD) patients.
Huanqiang Li +48 more
doaj +1 more source
Greenberger-Horne-Zeilinger paradox for continuous variables
, 2001 We show how to construct states for which a Greenberger-Horne-Zeilinger type paradox occurs if each party measures either the position or momentum of his particle.
A. Cabello +15 more
core +1 more source