Results 161 to 170 of about 8,962 (265)
NK Cell Activation by Platinum Boosts Immunotherapy in HR+/HER2− Breast Cancer
Multi‐omics and single‐cell analyses identify activated NK cells as key mediators of anti‐PD‐(L)1 response in HR+/HER2− breast cancer. Platinum chemotherapy enhances NK cell cytotoxicity through NF‐κB–associated signaling, synergizing with immunotherapy and providing a rationale for combination treatment.
Yi‐Yu Chen +8 more
wiley +1 more source
Living on the Edge: A Cocreated Teaching-Learning Journey. [PDF]
Ursel KL.
europepmc +1 more source
A novel “Cu‐mediated interstitial site engineering” strategy is introduced to thermodynamically stabilize hexagonal oxygen (hex‐O) configurations in oxygen‐containing titanium alloys. The hex‐O configuration activates multiple slip systems and enhances dislocation pinning via long‐range repulsion.
Xiaobin Lin +14 more
wiley +1 more source
The autonomy paradox in AI-generated content adoption: Creative-specific alternative to TAM model in China's micro-short drama industry. [PDF]
Tang C.
europepmc +1 more source
This study highlights that radioimmunotherapy drives crosstalk between fibroblasts and immune cells (especially macrophages) in the cardiac microenvironment, with IL‐6 as the key mediator, and tocilizumab alleviates cardiac fibrosis by targeting this interplay.
Yuxi Luo +10 more
wiley +1 more source
Critical Gaps in ARDS Prediction Models: A Call for Clinical Pragmatism [Letter]. [PDF]
Li J.
europepmc +1 more source
TRIM25 acts as a multifunctional hub driving intervertebral disc degeneration under mechanical stress. Mechanical compression significantly upregulates TRIM25 expression, establishing it as a key E3 ubiquitin ligase platform. TRIM25 targets PARG and Ku80 via distinct molecular interfaces, triggering their ubiquitination and degradation.
Zhangrong Cheng +9 more
wiley +1 more source
The Human Plastiphere: A Bioparticulate System Challenging Microplastic Risk Assessment and Governance. [PDF]
Shruti VC, Kutralam-Muniasamy G.
europepmc +1 more source

