Results 41 to 50 of about 254,286 (299)
Three Paradoxes of Supererogation [PDF]
, 2021 Supererogatory acts—good deeds “beyond the call of duty”—are a part of moral common sense, but conceptually puzzling. I propose a unified solution to three of the most infamous puzzles: the classic Paradox of Supererogation (if it’s so good, why isn’t it
Muñoz, Daniel
core
Molecular Oncology, EarlyView.We have established a humanized orthotopic patient‐derived xenograft (Hu‐oPDX) mouse model of high‐grade serous ovarian cancer (HGSOC) that recapitulates human tumor–immune interactions. Using combined anti‐PD‐L1/anti‐CD73 immunotherapy, we demonstrate the model's improved biological relevance and enhanced translational value for preclinical ...
Luka Tandaric +10 more
wiley +1 more source
Acquiring the Impossible: Developmental Stages of Copredication
Frontiers in Psychology, 2017 Much is known about the acquisition of phonological competence and lexical categories, but there has been substantially less research into word meaning development.
Elliot Murphy
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Paradoxes of neutrino oscillations [PDF]
, 2009 Despite the theory of neutrino oscillations being rather old, some of its basic issues are still being debated in the literature. We discuss, in the framework of the wave packet approach, a number of such issues, including the relevance of the "same ...
A. D. Dolgov +29 more
core +2 more sources
E2A selectively regulates TGF‐β–induced apoptosis in KRAS‐mutant non‐small cell lung cancer
Molecular Oncology, EarlyView.Ability to induce apoptosis by TGF‐β is frequently lost in advanced lung adenocarcinoma despite intact TGF‐β signaling. We identify E2A as a mutant KRAS–dependent mediator of resistance to TGF‐β–induced apoptosis. TGF‐β induces E2A via SMAD3 in mutant KRAS cells, and E2A silencing restores apoptosis and enhances radiation response in cell lines ...
Sergei Chuikov +3 more
wiley +1 more source
Are Zeno’s Arguments Unsound Paradoxes?
Peitho, 2013 Zeno’s arguments are generally regarded as ingenious but downright unsound paradoxes, worth of attention mainly to disclose why they go wrong or, alternatively, to recognise them as clever, even if crude, anticipations of modern views on the space, the ...
Guido Calenda
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Journal of Modern Science, 2021 Objectives The aims of the article focus on an evolutionary and retrospective look at the reality of contemporary public management in Poland in the second decade of the 21st century and considering the reality of public management in the convention of ...
Bogdan Nogalski +2 more
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Complexity, 1995 Lecture given Wednesday 27 October 1993 at a Physics -- Computer Science Colloquium at the University of New Mexico. The lecture was videotaped; this is an edited transcript. It also incorporates remarks made at the Limits to Scientific Knowledge meeting held at the Santa Fe Institute 24--26 May 1994.
openaire +4 more sources
Insights into a long life without cancer: The case of the bowhead whale
Molecular Oncology, EarlyView.Long‐lived, large‐bodied organisms have evolved powerful anticancer mechanisms that preserve cellular and tissue integrity across extended lifespans. A recent study by Firsanov et al. shows that greater genome stability is a key factor underlying the remarkable longevity and cancer resistance of one such species, the bowhead whale.
Inés Paniagua, Johanna A. Joyce
wiley +1 more source
Unveiling paradoxes: navigating SMEs readiness in the post-pandemic normality
Cogent Business & ManagementThis paper centers on the challenges posed by the pandemic crisis, examining the crucial organizational and strategic alignments, as well as the inherent paradoxes that are pivotal in nurturing competitiveness within the changed post-pandemic business ...
Rafael Castro, António Carrizo Moreira
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