Results 51 to 60 of about 254,286 (299)

Iron homeostasis disruption and lipid peroxidation in skeletal muscle during short‐term immobilization

open access: yesFEBS Open Bio, EarlyView.
14‐day casting‐induced immobilization reduced gastrocnemius muscle mass and increased non‐heme iron and ferritin heavy chain levels. Despite iron accumulation, transferrin receptor 1 and iron regulatory protein 2 were paradoxically upregulated. Lipid peroxidation was elevated without compensatory antioxidant responses.
Haruka Yokogawa   +2 more
wiley   +1 more source

Paradoxes of Nurse Training in the Context of the 70th Anniversary of Reanimatology

open access: yesОбщая реаниматология, 2006
Objective: To assess the professional education of nurses in the context of development of Russian reanimatology.Materials and methods. The official curriculums of nurse training over 70 years of Russian reanimatology were comparatively analyzed.Results.
A. I. Levshankov
doaj   +1 more source

Proteasomal degradation of intracellularly expressed Amblyomin‐X limits suicide gene therapy potential in melanoma cells

open access: yesFEBS Open Bio, EarlyView.
This study explores the feasibility of expressing the antitumoral protein Amblyomin‐X through a suicide gene therapy approach and investigates its intracellular fate after gene delivery. Although the gene is efficiently expressed, melanoma cells rapidly degrade the Amblyomin‐X protein via proteasome activity.
Victor Dal Posolo Cinel   +4 more
wiley   +1 more source

The logical challenge of negative theology

open access: yesStudies in Logic, Grammar and Rhetoric, 2018
In this paper I present four interpretations of so-called negative theology and provide a number of attempts to model this theory within a formal system. Unfortunately, all of them fail in some manner.
Urbańczyk Piotr
doaj   +1 more source

Paradoxical Behavior of Oncogenes Undermines the Somatic Mutation Theory

open access: yesBiomolecules, 2022
The currently accepted theory on the influence of DNA mutations on carcinogenesis (the Somatic Mutation Theory, SMT) is facing an increasing number of controversial results that undermine the explanatory power of mutated genes considered as “causative ...
Noemi Monti   +5 more
doaj   +1 more source

Paradoxes Review [PDF]

open access: yes, 1999
I came across one of the Smarandache divine paradoxes and felt very strongly that it is really our Buddhist·s obIigation to lhelp understand the uuderlying truth.
Liu, Feug
core   +1 more source

Acute caffeine treatment protects the developing retina from ischemia‐induced cell death

open access: yesFEBS Open Bio, EarlyView.
Caffeine reduces cell death in the developing retina under ischemia (OGD). This effect does not involve BDNF upregulation or antioxidant pathways (NRF2/VEGF). Neuroprotection occurs mainly through adenosine A2A receptor antagonism, decreasing glutamate release and excitotoxicity, highlighting caffeine's potential as an acute neuroprotective agent in ...
Amanda Alves Nascimento   +6 more
wiley   +1 more source

Lithuanian Law enforcement Officers on Aspects of Citizenship [PDF]

open access: yesKošická bezpečnostná revue, 2020
This paper presents some data from an empiric study carried out in Winter-Spring 2019, which was a presidential election and election to municipalities year in Lithuania; therefore, respondents had immediate and recent insights into issues related to ...
Vaiva ZUZEVIČIŪTĖ
doaj  

Pentagrams and paradoxes

open access: yes, 2009
Klyachko and coworkers consider an orthogonality graph in the form of a pentagram, and in this way derive a Kochen-Specker inequality for spin 1 systems.
A. Cabello   +28 more
core   +1 more source

Pharmacological inhibition of the PERK pathway modulates hepatocellular carcinoma growth and immune signaling

open access: yesFEBS Open Bio, EarlyView.
Pharmacological inhibition of PERK in a DEN‐induced mouse model of liver cancer does not reduce tumor burden but alters cellular stress signaling. Despite blocking PERK activity, downstream stress responses, including CHOP expression, remain active, suggesting compensatory mechanisms within the unfolded protein response that may influence tumor ...
Ada Lerma‐Clavero   +5 more
wiley   +1 more source

Home - About - Disclaimer - Privacy