Results 21 to 30 of about 802,938 (253)

Cellular liquid biopsy provides unique chances for disease monitoring, preclinical model generation and therapy adjustment in rare salivary gland cancer patients

Molecular Oncology, EarlyView.
We quantified and cultured circulating tumor cells (CTCs) of 62 patients with various cancer types and generated CTC‐derived tumoroid models from two salivary gland cancer patients. Cellular liquid biopsy‐derived information enabled molecular genetic assessment of systemic disease heterogeneity and functional testing for therapy selection in both ...
Nataša Stojanović Gužvić, Florian Lüke, Steffi Treitschke, Andrea Coluccio, Martin Hoffmann, Giancarlo Feliciello, Adithi Ravikumar Varadarajan, Xin Lu, Kathrin Weidele, Catherine Botteron, Silvia Materna–Reichelt, Felix Keil, Katja Evert, Florian Weber, Thomas Schamberger, Michael Althammer, Jirka Grosse, Dirk Hellwig, Christian Schulz, Stephan Seitz, Peter Ugocsai, Anke Schlenska‐Lange, Roman Mayr, Ulrich Kaiser, Wolfgang Dietmaier, Bernhard Polzer, Jens Warfsmann, Kamran Honarnejad, Tobias Pukrop, Daniel Heudobler, Christoph A. Klein, Christian Werno   +31 more
wiley   +1 more source

Crosstalk between gut microbiota and tumor: tumors could cause gut dysbiosis and metabolic imbalance

Molecular Oncology, EarlyView.
In this research, we analyzed the relationship between gut microbiota and tumor. We discovered that both subcutaneous and metastatic tumors would alter the composition and metabolic function of gut microbiota. Meanwhile, fecal microbiota transplantation also indicated the anti‐tumor role of the gut microbiota, revealing the crosstalk between tumor and ...
Siyuan Zhang, Haimei Wen, Ying Chen, Jingya Ning, Di Hu, Yujiao Dong, Chenyu Yao, Bo Yuan, Shuanying Yang   +8 more
wiley   +1 more source

A large sample study of spin relaxation and magnetometric sensitivity of paraffin-coated Cs vapor cells [PDF]

, 2009
We have manufactured more than 250 nominally identical paraffin-coated Cs vapor cells (30 mm diameter bulbs) for multi-channel atomic magnetometer applications. We describe our dedicated cell characterization apparatus.
A. Andalkar, A. Hofer, A. Weis, A. Weis, A. Weis, C. Macchione, D. Budker, D. Budker, D. Budker, E.B. Aleksandrov, E.B. Alexandrov, G. Ban, G. Bison, G. Bison, G. Bison, G. Di Domenico, G. Di Domenico, G. Di Domenico, H. Saudan, I.K. Kominis, Inc. Wolfram Research, J. Vanier, K.L. Corwin, M. Klein, N. Castagna, N.W. Ressler, P. Knowles, S. Gozzini, S. Groeger, S.F. Watanabe, T. Fernholz, W. Andrä, W.M. Itano   +32 more
core   +2 more sources

Analysis of comprehensive genomic profiling of solid tumors with a novel assay for broad analysis in clinical diagnostics

Molecular Oncology, EarlyView.
In molecular cancer diagnostics, comprehensive genomic profiling (CGP) is going to replace the small NGS panels since it provides all clinically relevant somatic variants as well as genomic biomarkers with clinical value. Here, we compared two CGP assays and demonstrate that the choice for diagnostic implementation will depend on the specific ...
Guy Froyen, Pieter‐Jan Volders, Ellen Geerdens, Severine Berden, Joni Van der Meulen, Aaron De Cock, Stefanie Vermeire, Jacques Van Huysse, Marie de Barsy, Gabriela Beniuga, Wendy W. J. de Leng, Anne M. L. Jansen, Imke Demers, Zeliha Ozgur, Hendrikus Jan Dubbink, Ernst‐Jan M. Speel, Wilfred F. J. van IJcken, Brigitte Maes   +17 more
wiley   +1 more source

Tissue Processor Based PLC (Programmable Logic Controller) [PDF]

, 2019
Tissue Processor Tissue Processor consists of consists of several stages of dehydration, clearing, and paraffin infiltration.Phase dehydration to remove water content in tissues by immersion into alcohol.
Ariswati, H. G. (Her), Indrato, T. B. (Tri), Neny, F. (Ferdianita)   +2 more
core  

Analysis of magnetic treatment of production fluid with high content of asphalt-resin-paraffin deposits [PDF]

, 2017
Purpose. Justification of magnetic field application in order to prevent formation of asphalt-resin-paraffin deposits (ARPD) in oil and gas equipment, and consider some current views on the state of ARPD problem in oilfield equipment and possible methods
Kharchenko, M, Lartseva, I, Manhura, A, Manhura, S   +3 more
core   +2 more sources

Response to neoadjuvant chemotherapy in early breast cancers is associated with epithelial–mesenchymal transition and tumor‐infiltrating lymphocytes

Molecular Oncology, EarlyView.
Epithelial–mesenchymal transition (EMT) and tumor‐infiltrating lymphocytes (TILs) are associated with early breast cancer response to neoadjuvant chemotherapy (NAC). This study evaluated EMT and TIL shifts, with immunofluorescence and RNA sequencing, at diagnosis and in residual tumors as potential biomarkers associated with treatment response.
Françoise Derouane, Jérôme Ambroise, Cédric van Marcke, Mieke Van Bockstal, Martine Berlière, Christine Galant, Hélène Dano, Médina Lougué, Elena Benidovskaya, Guy Jerusalem, Vincent Bours, Claire Josse, Jérôme Thiry, Aurélie Daumerie, Caroline Bouzin, Cyril Corbet, François P. Duhoux   +16 more
wiley   +1 more source

Human Pappilomavirus Genotype in Cervical Tissue of Patients with Cervical Intraepithelial Neoplasia (CIN) 1, CIN 2, and CIN 3 [PDF]

, 2016
Objectives: to determine the genotype of HPV in patients with precancerous lesions of cervical tissue.Materials and Methods: An observational study with cross sectional study of patients paraffin block CIN1, CIN2, CIN3 was conducted in Dr Soetomo ...
Alia, R. (Rahmi), I’tishom, R. (Renny), Mastutik, G. (Gondo), Rahaju, A. S. (Anny), Rahniayu, A. (Alphania)   +4 more
core   +1 more source

Nanostructured 3D Constructs Based on Chitosan and Chondroitin Sulphate Multilayers for Cartilage Tissue Engineering [PDF]

, 2013
Nanostructured three-dimensional constructs combining layer-by-layer technology (LbL) and template leaching were processed and evaluated as possible support structures for cartilage tissue engineering.
AM Martins, AR Fajardo, BC Heng, C Albrecht, C Chung, C Detzel, C Kirkpatrick, C Vinatier, Clemens A. Van Blitterswijk, D Puppi, E Miranda, EJ Menzel, FH Chen, FT Moutos, GV Martins, H Fan, J Almodo?var, JF Mano, JF Mano, JF Piai, JK Francis Suh, JM Sobral, JM Varghese, Joana M. Silva, João F. Mano, JRE Fraser, JS Mao, JS Pieper, JS Temenoff, K Anselme, K Köhler, K Von Der Mark, L Wu, L-P Yan, L-P Yan, M Kubo, Marcel Karperien, MV Voinova, Mário A. Barbosa, Nicole Georgi, NM Alves, O Franke, P Sher, Praveen Sher, R Jin, R Servaty, RG LeBaron, RR Costa, RR Costa, Rui Costa, Rui L. Reis, S Chatterjee, S Ghosh, S-H Lee, SC Neves, T Boudou, T Crouzier, W Sui, W-C Chen, WH Dietmar, Y Gong, Y Liu, Z Tang   +62 more
core   +4 more sources

Multiplex single‐cell profiling of putative cancer stem cell markers ALDH1, SOX9, SOX2, CD44, CD133 and CD15 in endometrial cancer

Molecular Oncology, EarlyView.
Cancer stem cells are associated with aggressive disease, but a deep characterization of such markers is lacking in endometrial cancer. This study uses imaging mass cytometry to explore putative cancer stem cell markers in endometrial tumors and corresponding organoid models.
Hilde E. Lien, Marta E. Hjelmeland, Hege F. Berg, Rose M. Gold, Kathrine Woie, Lars A. Akslen, Ingfrid S. Haldorsen, Camilla Krakstad   +7 more
wiley   +1 more source