Results 61 to 70 of about 576,291 (256)

An Electronic Nose Based Method for the Discrimination of Weathered Petroleum-Derived Products

Sensors, 2018
In recent years pollution due to hydrocarbon spills has increased markedly as a result of the numerous advances in technologies and industrial processes. Anthropogenic activities (accidental or illegal) are responsible for most of these incidents.
María José Aliaño-González, Marta Ferreiro-González, Gerardo F. Barbero, Jesús Ayuso, José A. Álvarez, Miguel Palma, Carmelo G. Barroso   +6 more
doaj   +1 more source

Establishment of a humanized patient‐derived xenograft mouse model of high‐grade serous ovarian cancer for preclinical evaluation of combination immunotherapy

Molecular Oncology, EarlyView.
We have established a humanized orthotopic patient‐derived xenograft (Hu‐oPDX) mouse model of high‐grade serous ovarian cancer (HGSOC) that recapitulates human tumor–immune interactions. Using combined anti‐PD‐L1/anti‐CD73 immunotherapy, we demonstrate the model's improved biological relevance and enhanced translational value for preclinical ...
Luka Tandaric, Line Bjørge, Martine Rott Lode, Cecilie Fredvik Torkildsen, Pia Aehnlich, Rammah Elnour, Daniela Elena Costea, Lars Andreas Akslen, Liv Cecilie Vestrheim Thomsen, Emmet McCormack, Katrin Kleinmanns   +10 more
wiley   +1 more source

Optimization of Oil Production Using Sucker Rod Pumps via Predictive Elimination of Paraffin Issues

Applied Sciences
This paper explores the application of predictive maintenance (PdM) to address paraffin deposition in sucker rod pump systems used for oil production.
Stevica Jankov, Borivoj Novaković, Milan Marković, Uroš Šarenac, Dejan Landup, Velibor Premčevski, Luka Đorđević   +6 more
doaj   +1 more source

THERMAL CHARACTERISTICS OF PHASE CHANGE MATERIAL USED AS THERMAL STORAGE SYSTEM BY USING SOLAR ENERGY

Mağallaẗ Al-kūfaẗ Al-handasiyyaẗ, 2018
In this paper, the melting processes of phase change material in a shell and tube heat exchanger by using solar thermal energy have been investigated numerically and experimentally.
Kadhim F. Nasir, Munir Ali, Ameer H. AL Mamoori   +2 more
doaj   +1 more source

Deciphering transcriptional plasticity in pancreatic ductal adenocarcinoma reveals alterations in sensory neuron innervation

Molecular Oncology, EarlyView.
Pancreatic sensory neurons innervating healthy and PDAC tissue were retrogradely labeled and profiled by single‐cell RNA sequencing. Tumor‐associated innervation showed a dominant neurofilament‐positive subtype, altered mitochondrial gene signatures, and reduced non‐peptidergic neurons.
Elena Genova, Michele Montrone, Uday Rangaswamy, Francesco Diversi, Irene Schiavo, Denise Ferrarini, Roberta Di Florio, Irene Longo, Michele Coscia, Nicola Zamboni, Giorgia Demontis, Lisa Veghini, Vincenzo Corbo, Remo Sanges, Paul Heppenstall   +14 more
wiley   +1 more source

Overview of molecular signatures of senescence and associated resources: pros and cons

FEBS Open Bio, EarlyView.
Cells can enter a stress response state termed cellular senescence that is involved in various diseases and aging. Detecting these cells is challenging due to the lack of universal biomarkers. This review presents the current state of senescence identification, from biomarkers to molecular signatures, compares tools and approaches, and highlights ...
Orestis A. Ntintas, Sylvia Vagena, Pavlos Pantelis, Giorgos Theocharous, Russel Petty, Konstantinos Evangelou, Vassilis G. Gorgoulis   +6 more
wiley   +1 more source

Targeting TNBC: core–shell polycationic polyurea dendrimers with inherent anticancer activity

FEBS Open Bio, EarlyView.
Core–shell polycationic PURE dendrimers were tested in TNBC‐derived tumor models. Both formulations selectively targeted TNBC and effectively reduced tumor volume. PUREG4‐OEI48 suppressed tumor growth without detectable toxicity, whereas PUREG4‐OCEI24, despite showing efficacy, induced hepatic toxicity.
Adriana Cruz, Bruna Abreu, Cindy Mendes, Catarina Freitas‐Dias, Filipe Gonçalves, Fernanda Silva, José Ramalho, Saudade André, Vasco D. B. Bonifácio, Jacinta Serpa   +9 more
wiley   +1 more source

Prediction of the Viscosity-Temperature Dependence of a Mixture of Oils Based on Information about the Density, Content of Paraffin, Resins, Asphaltenes and Fractional Composition

Georesursy
The article is devoted to the problem of predicting the viscosity of an oil mixture. Viscosity is an important characteristic of oil when calculating pressure losses due to friction when moving in a well, through field pipelines, through a network of ...
A. R. Valeev, R. R. Tashbulatov, Y. Chen, R. M. Karimov   +3 more
doaj   +1 more source

Comparison of SVM, RF and ELM on an Electronic Nose for the Intelligent Evaluation of Paraffin Samples

Sensors, 2018
Paraffin odor intensity is an important quality indicator when a paraffin inspection is performed. Currently, paraffin odor level assessment is mainly dependent on an artificial sensory evaluation.
Hong Men, Songlin Fu, Jialin Yang, Meiqi Cheng, Yan Shi, Jingjing Liu   +5 more
doaj   +1 more source

Pathogenic Neurofibromatosis type 1 gene variants in tumors of non‐NF1 patients and role of R1276

FEBS Open Bio, EarlyView.
Somatic variants of the neurofibromatosis type 1 (NF1) gene occur across neoplasms without clinical manifestation of the disease NF1. We identified emerging somatic pathogenic NF1 variants and hotspots, for example, at the arginine finger 1276. Those missense variants provide fundamental information about neurofibromin's role in cancer.
Mareike Selig, Swanhild Lohse, Sara Elahi, Nils Hartmann, Stefanie Deckert, Shutian Si, Alexander Desuki, Anja Harder   +7 more
wiley   +1 more source