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The DI–DII linker of human parainfluenza virus type 3 fusion protein is critical for the virus

Virus Genes, 2019
Human parainfluenza virus type 3 (HPIV3) causes the majority of childhood viral pneumonia around the world. Fusing the viral and target cell membranes is crucial for its entry into target cells, and the fusion process requires the concerted actions of two viral glycoproteins: hemagglutinin-neuraminidase (HN) and fusion (F) protein. After binding to the
Ying, Liu   +7 more
openaire   +2 more sources

Mapping of an Antigenic Site on the Nucleocapsid Protein of Human Parainfluenza Virus Type 3

Viral Immunology, 2009
Human parainfluenza virus type 3 (hPIV3) is a respiratory tract pathogen. The current study aimed to investigate immunodominant regions of hPIV3 nucleocapsid (N) protein by using monoclonal antibodies (mAbs) raised against recombinant N protein and human serum specimens from hPIV3-infected individuals.
Aurelija, Zvirbliene   +5 more
openaire   +2 more sources

ISGylation during Human Parainfluenza Virus Type 3 Infection

The Journal of Immunology
Abstract Human parainfluenza virus type 3 (HPIV3) causes lower respiratory illnesses such as pneumonia or bronchiolitis in infants, young children, and the immunocompromised. HPIV3 associated airway inflammatory diseases manifest as a result of host mediated exaggerated inflammatory response, though limited knowledge exists regarding ...
Lindsay Miller   +3 more
openaire   +1 more source

Characterization of the fusion protein of the human parainfluenza virus type 3

2013
Human parainfluenza virus type 3 (HPIV3), a member of the family Paramyxoviridae, is an enveloped, negative-sense single stranded RNA virus, and an important cause of upper and lower respiratory tract disease in children. Infection by HPIV3 requires fusion of the viral envelope with the plasma membrane of the host cell.
openaire   +2 more sources

The sequence of the L gene of the human parainfluenza 3 virus

Virus Research, 1988
Mark R. Galinski   +2 more
openaire   +1 more source

Human parainfluenza virus circulation, United States, 2011–2019

Journal of Clinical Virology, 2020
Marie E Killerby   +2 more
exaly  

STRUCTURAL CHARACTERIZATION OF HUMAN PARAINFLUENZA VIRUS 3

1984
Douglas G. Storey, C. Yong Kang
openaire   +1 more source

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