Results 41 to 50 of about 55,383 (212)

ISG56/IFIT1 is primarily responsible for interferon-induced changes to patterns of parainfluenza virus type 5 transcription and protein synthesis

, 2013
This work was supported by the Wellcome Trust.Interferon (IFN) induces an antiviral state in cells that results in alterations of the patterns and levels of parainfluenza virus type 5 (PIV5) transcripts and proteins.
Goodbourn, S, Norsted, H., Randall, RE, Andrejeva, J., Thiel, V., Habjan, M, Habjan, M., Goodbourn, S., Norsted, H, Thiel, V, Randall, R. E., Andrejeva, J   +11 more
core   +1 more source

Can epilepsy be predicted after the first febrile seizure? Insights from machine learning of postictal EEG

Epileptic Disorders, EarlyView.
Abstract Objective Febrile seizures (FS) are the most common seizures in childhood, yet identifying children at risk of developing epilepsy after the first FS remains challenging. We aimed to evaluate the prognostic potential of machine learning (ML) algorithms applied to post‐febrile seizure electroencephalography (EEG) recordings.
Boran Şekeroğlu, Hüseyin Öztoprak, Özlem Yayıcı Köken, Hatice Demir, Mehpare Sarı Yanartaş, Deniz Yılmaz, Burçin Şanlıdağ, Ayşegül Neşe Çıtak Kurt   +7 more
wiley   +1 more source

Evidence‐based guideline for clinical practice in the diagnosis, treatment, management, and prevention of recurrent wheezing in infants and toddlers in China

Pediatric Investigation, EarlyView.
ABSTRACT Wheezing is a common respiratory symptom in infants and toddlers, and recurrent wheezing is a significant respiratory disorder affecting this age group. Given the multifactorial etiology of recurrent wheezing, clinical practice lacks standardized diagnostic and therapeutic protocols. Recent years have witnessed substantial progress in clinical
Committee of Pediatrics, China Medical Education Association, Cooperative Group of Asthma, the Subspecialty Group of Respiratory, the Society of Pediatrics, Chinese Medical Association, Pediatric Respiratory Work Committee, Society of Pulmonologists, Chinese Medical Doctor Association, Committee of Pediatrics, Chinese Research Hospital Association, Pediatric Professional Committee of the Chinese Non‐public Medical Institutions Association, Professional Committee of Children's Health and Pharmaceutical Research, China Association of Traditional Chinese Medicine, Children's Safe Medication Branch of China News of Drug Information Association, Pediatric Expert Committee of China Primary Health Care Foundation, China International Medical Foundation   +16 more
wiley   +1 more source

RNA editing in the phosphoprotein gene of the human parainfluenza virus type 3

Virology, 1992
RNA editing of the human parainfluenza virus type 3 (HPIV3) phosphoprotein (P) gene was found to occur for the accession of an alternate discontinuous cistron. Editing occurred within a purine-rich sequence (AAUUAAAAAAGGGGG) found at the mRNA nucleotides 791-805.
Galinski, Mark S., Troy, Roberta M., Banerjee, Amiya K.   +2 more
openaire   +2 more sources

Modulation of immune responses by human paraininfluenza virus [PDF]

, 2007
Human Parainfluenza virus type 3 (HPIV3) is a key respiratory pathogen responsible for bronchiolitis, pneumonia and croup. The persistent nature of this virus and its ability to reinfect within a short space of time has led to successive failures in the ...
Noone, Cariosa
core  

Reusing health records from farm animal practices at scale: A potential complementary method of surveillance

Veterinary Record, EarlyView.
Abstract Background Disease in primary care frequently represents a surveillance blind spot, particularly for diseases affecting farm animals. Methods Electronic health records (EHRs) were collected from four farm animal veterinary practices in Wales (February 2024‒January 2025) as part of a pilot study.
Beverley Hopkins, Peers Davies, Peter‐John Noble, Anna Bunford‐Davies, April Lawson, Gina Pinchbeck, Ifan Lloyd, Robert Smith, Alan D. Radford   +8 more
wiley   +1 more source

Characterization of the Oligomerization Domain of the Phosphoprotein of Human Parainfluenza Virus Type 3

Virology, 2002
The phosphoprotein (P) of human parainfluenza virus type 3 (HPIV 3) plays a central role in the viral genome RNA transcription and replication. It acts as an essential cofactor of the RNA polymerase (L) by forming a functional L-P complex, binds to the genomic N-RNA template to recruit the L-P complex for RNA synthesis, and interacts with the ...
Choudhary, Suresh K., Malur, Achut G., Huo, Yunwen, De, Bishnu P., Banerjee, Amiya K.   +4 more
openaire   +2 more sources

Mumps virus Enders strain is sensitive to interferon (IFN) despite encoding a functional IFN antagonist

, 2009
Although the Enders strain of mumps virus (MuV) encodes a functional V protein that acts as an interferon (IFN) antagonist, in multi-cycle growth assays MuV Enders grew poorly in naive ('IFN-competent' Hep2) cells but grew to high titres in 'IFN ...
Rima, B K, Andrejeva, Jelena, K. Lemon, B. K. Rima, Duprex, P, W. P. Duprex, M. C. Galiano, Galiano, M, J. Andrejeva, D. F. Young, R. E. Randall, Young, D F, Lemon, K, Chen, Y-H, Y.-H. Chen, Randall, Richard Edward   +15 more
core   +1 more source

A fatal case of neonatal viral sepsis caused by human parainfluenza virus type 3

Virology Journal, 2023
Background Sepsis is a systemic inflammatory response syndrome caused by severe infection in children, but cases of sepsis associated with human parainfluenza virus (HPIV) have been rarely reported in newborns.
Xiangpeng Chen, Hong Wang, Qi Li, Yujie Qi, Fei Li, Wenwen He, Qiushi Wang, Fei Jin, Yanqing Guo, Mingyan Hei, Zhengde Xie   +10 more
doaj   +1 more source

Ecology of reintroduced Rocky Mountain bighorn sheep in Dinosaur National Monument La Ecología de Borrego Cimarron de las Montañas Rocosas Reintroducido en el Monumento Nacional de Dinosaurio

Wildlife Monographs, EarlyView.
We synthesized GPS telemetry, genetic, and pathogen data to evaluate metapopulation processes in a reintroduced Rocky Mountain bighorn sheep (Ovis canadensis canadensis) population in Dinosaur National Monument. We estimated subpopulation‐specific abundances and found 4 small subpopulations with high genetic diversity, partial connectivity, and ...
Sarah L. Carroll, Elizabeth P. Flesch, Salix R. Scoresby, Emily Spencer, Rachel S. Crowhurst, Clinton W. Epps, Nathan L. Galloway, William M. Janousek, Tabitha A. Graves   +8 more
wiley   +1 more source