Characterization of human parainfluenza virus type 3 persistent infection in cell culture [PDF]
Three cell lines persistently infected with human parainfluenza virus type 3 were characterized on a molecular level in this study. All six structural protein genes were transcribed into monocistronic RNAs in the persistently infected cells. In both acutely and persistently infected cells, polycistronic transcripts were abundant, although the ratio of ...
A, Moscona, M S, Galinski
openaire +2 more sources
Parainfluenza virus infection in an Australian community-based birth cohort
In a community-based birth cohort of 158 Australian infants followed to age 2 years, the incidence rate of human parainfluenza virus (HPIV) was 0.42 (95% CI = 0.33, 0.54) episodes per child-year with episodes occurring year-round, peaking in the spring ...
Sarna, Mohinder +12 more
core +1 more source
Objective: To determine the incidence of respiratory viral infections in bone marrow transplant patients. Method: The prospective, descriptive, cross-sectional study was conducted at a tertiary care hospital in Rawalpindi, Pakistan, from September ...
Noman Shakoor +5 more
doaj +1 more source
Recovery of Infectious Human Parainfluenza Virus Type 3 from cDNA
Infectious HPIV3 was produced by the intracellular coexpression of four plasmid-borne cDNAs. These separately encoded a complete HPIV3 genome (negative-sense), the HPIV3 nucleocapsid protein N, the phosphoprotein P, and the polymerase protein L. The cDNA-encoded HPIV3 genome differed from the JS wildtype (wt) strain of HPIV3 used in its construction by
Durbin, Anna P. +5 more
openaire +2 more sources
Evaluating a parainfluenza virus 5-based vaccine in a host with pre-existing immunity against parainfluenza virus 5. [PDF]
Parainfluenza virus 5 (PIV5), formerly known as simian virus 5 (SV5), is a paramyxovirus often referred to as canine parainfluenza virus (CPI) in the veterinary field. PIV5 is thought to be a contributing factor to kennel cough.
Zhenhai Chen +6 more
doaj +1 more source
Dengue virus inhibits alpha interferon signaling by reducing STAT2 expression
Type 1 interferons (IFN-?/?) are key mediators of innate antiviral responses but havelittle effect on established replication of dengue viruses, which are mosquito-borneflaviviruses of immense global health importance.
Jones, M +9 more
core +1 more source
Deep sequencing analysis of defective genomes of parainfluenza virus 5 and their role in interferon induction [PDF]
This work was supported by The Wellcome Trust (087751/A/08/Z).Preparations of parainfluenza virus 5 (PIV5) that are potent activators of the interferon (IFN) induction cascade were generated by high-multiplicity passage in order to accumulate defective ...
Killip, M. J. +13 more
core +1 more source
Respiratory Viruses Associated Hospitalization among Children Aged <5 Years in Bangladesh: 2010-2014. [PDF]
BACKGROUND:We combined hospital-based surveillance and health utilization survey data to estimate the incidence of respiratory viral infections associated hospitalization among children aged < 5 years in Bangladesh.
Nusrat Homaira +17 more
doaj +1 more source
Transient marked reactive lymphocytosis in a puppy suspected to be secondary to recent vaccination
A 3‐month‐old male Bernese Mountain dog was presented with a 10‐day history of vomiting, vocalisation and abdominal discomfort following vaccination. Physical examination revealed subtle peripheral lymphadenopathy. Haematological testing revealed borderline anaemia, thrombocytopenia and moderate lymphocytosis with a high proportion of reactive or ...
J. Ruel +5 more
wiley +1 more source
The terminal globular domain of the paramyxovirus hemagglutinin-neuraminidase (HN) glycoprotein spike has a number of conserved residues that are predicted to form its neuraminidase (NA) active site, by analogy to the influenza virus neuraminidase ...
Paul J. Mahon +13 more
core +1 more source

