Results 51 to 60 of about 253,501 (314)

Parallel Solution Algorithm for the Multi-Group Particle Transport Equations on the Unstructured Meshes

Journal of Algorithms & Computational Technology, 2010
The numerical simulations for solving the transport equations lead to the large computation and need to implement parallel calculation. On the unstructured grids, the communicating delays, sorting algorithms and inserting algorithms limit the performance
Liu Jie, Chi Li-Hua, Chen Jing, Zhuo Hongbin, Xu Han, Jiang Jie, Hu Qing-Feng   +6 more
doaj   +1 more source

MITF maintains genome stability in nonmelanocyte lineages

Molecular Oncology, EarlyView.
MITF is essential for melanocyte survival and acts as an oncogene in 10%–20% of melanomas. We show that MITF depletion causes genome instability in nonmelanocytic cells, leading to LATS2‐mediated P53 activation, cell cycle arrest, and apoptosis. This study highlights the role of MITF as a genome maintenance factor beyond the melanocyte lineage. Created
Drifa H. Gudmundsdottir, Adrián López García de Lomana, Thejus B. Venkatesh, Kritika Kirty, Snaevar Sigurdsson, Linda Vidarsdottir, Ramile Dilshat, Erla Sveinbjornsdottir, Snaedis Ragnarsdottir, Daniel H Magnusson, Maria R. Bustos, Eirikur Steingrimsson, Thorkell Gudjonsson, Stefan Sigurdsson   +13 more
wiley   +1 more source

A novel quinazolinone insulin receptor inhibitor and its synergy with an EGFR inhibitor in glucose‐driven glioblastoma

Molecular Oncology, EarlyView.
The novel styrylquinazolinone‐based molecule W1B effectively suppresses glioblastoma by inhibiting IGF1R and EGFR. In high‐glucose microenvironments driving tumor resistance, W1B acts synergistically with the EGFR inhibitor dacomitinib. This combination safely blocks compensatory survival signaling in zebrafish xenograft models. Showcasing promising in
Patryk Rurka, Wioleta Cieślik, Wojciech Płaziński, Katarzyna Stępnik, Anna Boguszewska‐Czubara, Elżbieta Kot, Robert Musioł, Mateusz Jasica, Anna Mrozek‐Wilczkiewicz, Katarzyna Malarz   +9 more
wiley   +1 more source

Patient therapy outcome modeling in cancer organoids is improved by cancer‐associated fibroblasts and organoid assembly convolution

Molecular Oncology, EarlyView.
Patient‐derived organoids (PDOs) from pancreatic, colorectal, and gastric cancers were used to evaluate standard and experimental therapies. Incorporating cancer‐associated fibroblasts (CAFs) into organoid cultures improved patient therapy outcome prediction.
Marcin Grochowski, Liudmyla Dolinchuk, Michał Jerzak, Albert Gandurski, Tomasz Grochowski, Weronika Wojtyś, Maciej Zadrożny, Wojciech Kaźmierczak, Małgorzata Lenarcik, Marta Matejak‐Górska, Radosław Samsel, Tomasz Olesiński, Dawid Walerych   +12 more
wiley   +1 more source

THE SYSTEM OFVIRTUAL LABORATORY PRACTICE ON PARALLEL ALGORITHMS

Вестник Кемеровского государственного университета, 2013
The present work describes a system of virtual laboratory practice on parallel computing. This system allows the user access to the theoretical material, as well as parallel computing servers of Kemerovo State University Common Use Center.
I. V. Grigorieva, Yu. V. Savitskiy
doaj  

Hybrid CPU-GPU Community Detection in Weighted Networks

IEEE Access, 2020
Recently, a new trend has emerged in the field of parallel and high performance computing, the hybrid implementation using CPU-GPU modules. In such implementations, the computational load is shared between the CPU and GPU, in order to improve the ...
Stavros Souravlas, Angelo Sifaleras, Stefanos Katsavounis   +2 more
doaj   +1 more source

Direct Bulk-Synchronous Parallel Algorithms

, 2022
We describe a methodology for constructing parallel algorithms that are transportable among parallel computers having different numbers of processors, different bandwidths of interprocessor communication and different periodicity of global ...
Gerbessiotis, A.V., Valiant, Leslie
core   +1 more source

Automated FRAP microscopy for high‐throughput analysis of protein dynamics in chromatin organization and transcription

FEBS Open Bio, EarlyView.
RoboMic is an automated confocal microscopy pipeline for high‐throughput functional imaging in living cells. Demonstrated with fluorescence recovery after photobleaching (FRAP), it integrates AI‐driven nuclear segmentation, ROI selection, bleaching, and analysis.
Selçuk Yavuz, Bart Geverts, Johan A. Slotman, Andrea Sacchetti, Stefan Prekovic, Martin E. van Royen, Adriaan B. Houtsmuller   +6 more
wiley   +1 more source

Cover Edge-Based Novel Triangle Counting

Algorithms
Counting and listing triangles in graphs is a fundamental task in network analysis, supporting applications such as community detection, clustering coefficient computation, k-truss decomposition, and triangle centrality.
David A. Bader, Fuhuan Li, Zhihui Du, Palina Pauliuchenka, Oliver Alvarado Rodriguez, Anant Gupta, Sai Sri Vastav Minnal, Valmik Nahata, Anya Ganeshan, Ahmet Cemal Gundogdu, Jason Lew   +10 more
doaj   +1 more source

Polarization‐resolved femtosecond Vis/IR spectroscopy tailored for resolving weak signals in biological samples using minimal sample volume

FEBS Open Bio, EarlyView.
Unique biological samples, such as site‐specific mutant proteins, are available only in limited quantities. Here, we present a polarization‐resolved transient infrared spectroscopy setup with referencing to improve signal‐to‐noise tailored towards tracing small signals. We provide an overview of characterizing the excitation conditions for polarization‐
Clark Zahn, Karsten Heyne
wiley   +1 more source