Results 91 to 100 of about 1,515,905 (267)

From mice to humans—divergent strategies for intestinal homeostasis and regeneration

open access: yesFEBS Letters, EarlyView.
Recent advances such as organoid genome editing, xenotransplantation, imaging, and whole‐genome sequencing have enabled direct studies of human intestinal stem cells (ISCs). These studies reveal species‐specific features, including slower ISC proliferation, distinct injury responses, slower somatic mutation accumulation in humans, and an inverse ...
Keiko Ishikawa   +2 more
wiley   +1 more source

Psychometric evaluation and factor structure of the Persian coping strategies questionnaire in chronic low back pain patients

open access: yesJournal of Current Oncology and Medical Sciences
Introduction: This study aimed to investigate the factor structure and psychometric properties of the Coping Strategies Questionnaire (CSQ) in Persian in people with non-specific chronic low back pain (NSCLBP).
Sarvenaz Karimi-GhasemAbad   +6 more
doaj  

Structural insights and therapeutic targets in Acinetobacter baumannii capsule biosynthesis

open access: yesFEBS Letters, EarlyView.
Hypervirulent KL49 A. baumannii's capsular polysaccharide contains the nonulosonic acid 8‐epi‐Leg5,7Ac2, synthesized by epimerization via ElaA, ElaB, and ElaC. Crystal structures of ElaA, ElaB, and ElaC reveal their role in CMP‐Leg5,7Ac2 synthesis and regioselective C8 epimerization.
Woo Cheol Lee   +7 more
wiley   +1 more source

A Survey of Galaxy Pairs in the SDSS Photometric Images based on Faster-RCNN

open access: yesThe Astronomical Journal
Galaxy pairs hold significant importance in understanding the evolution of galaxies, and the extensive search for a large sample of galaxy pairs is meaningful.
Chen-hui Shi   +7 more
doaj   +1 more source

Parallelized Program Analysis.

open access: yes, 2010
This thesis presents a framework for parallelized program analysis. It uses available parallel processing power in standard desktop computers to speed up static program analysis. Today, processor chip manufacturers produce single processor chips containing multiple cores, each with a processing power of previous single-core processors.
openaire   +1 more source

Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment

open access: yesMolecular Oncology, EarlyView.
This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley   +1 more source

Dimethyl fumarate combined with cisplatin at subcytotoxic doses sensitizes cervical cancer toward ferroptosis and apoptosis through GSH restriction and p53 (re)activation

open access: yesMolecular Oncology, EarlyView.
Dimethyl fumarate (DMF) reduces growth of HPV‐positive cervical cancer spheroids and induces ferroptosis in cervical cancer cells via blocking SLC7A11/Glutathione (GSH) axis. Combination of subcytotoxic doses of DMF and cisplatin (CDDP) further suppresses spheroid growth and drives cell death in 2D culture models.
Carolina Punziano   +6 more
wiley   +1 more source

2RPS/2SPS Parallel Mechanism and Kinematics Analysis

open access: yesJixie chuandong, 2020
Based on constraint spiral theory,the modified Grübler-Kutzbach formula is used to analyze the degree of freedom of 2RPS/2SPS parallel mechanism. The inverse positional solution equation is established by the space coordinate transformation equation and ...
Zhou Yijun, Chen Yefu, Su Ronghai
doaj  

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