Determining Parallel Analysis Criteria
Journal of Modern Applied Statistical Methods, 2005 Exploratory factor analysis is an important analytic tool for investigating test validity. Of all the decisions made in exploratory factor analysis, determining the number of factors to extract is perhaps the most critical because incorrect specification will obscure the factor structure (Cattell, 1978; Glorfeld, 1995; Goodwin & Goodwin, 1999 ...
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Correlation of the differential expression of PIK3R1 and its spliced variant, p55α, in pan‐cancer
Molecular Oncology, EarlyView.PIK3R1 undergoes alternative splicing to generate the isoforms, p85α and p55α. By combining large patient datasets with laboratory experiments, we show that PIK3R1 spliced variants shape cancer behavior. While tumors lose the protective p85α isoform, p55α is overexpressed, changes linked to poorer survival and more pronounced in African American ...
Ishita Gupta +10 more
wiley +1 more source
Parallel analysis of RNA ends reveals global microRNA-mediated target RNA cleavage in maize. [PDF]
Plant J, 2022 He J +6 more
europepmc +1 more source
Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment
Molecular Oncology, EarlyView.This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley +1 more source
2RPS/2SPS Parallel Mechanism and Kinematics Analysis
Jixie chuandong, 2020 Based on constraint spiral theory，the modified Grübler-Kutzbach formula is used to analyze the degree of freedom of 2RPS/2SPS parallel mechanism. The inverse positional solution equation is established by the space coordinate transformation equation and ...
Zhou Yijun, Chen Yefu, Su Ronghai
doaj
CometChip enables parallel analysis of multiple DNA repair activities. [PDF]
DNA Repair (Amst), 2021 Ge J +13 more
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Basroparib inhibits YAP‐driven cancers by stabilizing angiomotin
Molecular Oncology, EarlyView.Basroparib, a selective tankyrase inhibitor, suppresses Wnt signaling and attenuates YAP‐driven oncogenic programs by stabilizing angiomotin. It promotes AMOT–YAP complex formation, enforces cytoplasmic YAP sequestration, inhibits YAP/TEAD transcription, and sensitizes YAP‐active cancers, including KRAS‐mutant colorectal cancer, to MEK inhibition.
Young‐Ju Kwon +4 more
wiley +1 more source
Parallel analysis of transcription, integration, and sequence of single HIV-1 proviruses. [PDF]
Cell, 2022 Einkauf KB +14 more
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Molecular Oncology, EarlyView.To integrate multiple transcriptomics data with severe batch effects for identifying MB subtypes, we developed a novel and accurate computational method named RaMBat, which leveraged subtype‐specific gene expression ranking information instead of absolute gene expression levels to address batch effects of diverse data sources.
Mengtao Sun, Jieqiong Wang, Shibiao Wan
wiley +1 more source
Parallel analysis of multiple human memory CD4+ T-cell subsets within antigen-specific responses using cell proliferation dyes. [PDF]
Immunol Cell Biol, 2023 Cook L +5 more
europepmc +1 more source