Results 61 to 70 of about 1,526,420 (267)

Structural insights into an engineered feruloyl esterase with improved MHET degrading properties

FEBS Letters, EarlyView.
A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa, Konstantinos Makryniotis, Theofani‐Iosifina Sousani, Evangelos Topakas, Vangelis Daskalakis, Maria Dimarogona   +5 more
wiley   +1 more source

Parallel coupled ring resonators performance analysis

Results in Physics, 2019
We have investigated the system performance of several parallel coupled ring resonators. An optical network analyzer is utilized to analyze the output spectrums (frequency response) from the throughput and drop ports of the proposed system while it is ...
Satish Addanki, I.S. Amiri, P. Yupapin
doaj   +1 more source

Valosin‐containing protein counteracts ATP‐driven dissolution of FUS condensates through its ATPase activity in vitro

FEBS Letters, EarlyView.
Biomolecular condensates formed by fused in sarcoma (FUS) are dissolved by high ATP concentrations yet persist in cells. Using a reconstituted system, we demonstrate that valosin‐containing protein (VCP), an AAA+ ATPase, counteracts ATP‐driven dissolution of FUS condensates through its D2 ATPase activity.
Hitomi Kimura, Shin‐ichi Tate, Kyota Yasuda   +2 more
wiley   +1 more source

Diversity and complexity in neural organoids

FEBS Letters, EarlyView.
Neural organoid research aims to expand genetic diversity on one side and increase tissue complexity on the other. Chimeroids integrate multiple donor genomes within single organoids. Self‐organising multi‐identity organoids, exogenous cell seeding, or enforced assembly of region‐specific organoids contribute to tissue complexity.
Ilaria Chiaradia, Madeline A. Lancaster
wiley   +1 more source

Hyperosmotic stress induces PARP1‐mediated HPF1‐dependent mono(ADP‐ribosyl)ation

FEBS Letters, EarlyView.
Sorbitol‐induced hyperosmotic stress rapidly induces reversible mono(ADP‐ribosyl)ation (MARylation) on PARP1 without the signs of genotoxic signaling. We show that PARP1 autoMARylation is HPF1 dependent and forms hydroxylamine‐resistant O‐glycosidic linkages.
Anna Georgina Kopasz, Mihály Mérey, Rebeka Vásárhelyi, Ramóna Pék, Victor Imburchia, László Henn, Adrián Kószó, Nicholas D. Lakin, Ivan Ahel, Sébastien Huet, Ágnes Czibula, Gyula Timinszky   +11 more
wiley   +1 more source

An isoform of 14‐3‐3 protein regulates transbilayer lipid movement at the plasma membrane

FEBS Letters, EarlyView.
Loss of 14‐3‐3ζ in CHO cells confers resistance to exogenous phosphatidylserine (PS) and impairs endocytosis‐independent inward flip‐flop of fluorescent PS at the plasma membrane. RNAi‐mediated knockdown reproduces this defect, while no additive effect is seen in ATP11C‐deficient cells.
Akiko Yamaji‐Hasegawa, Akira Hattori, Masafumi Tsujimoto, Toshihide Kobayashi   +3 more
wiley   +1 more source

Partitioning Dichotomous Items Using Mokken Scale Analysis, Exploratory Graph Analysis and Parallel Analysis: A Monte Carlo Simulation

Methodology
Estimating the number of latent factors underlying a set of dichotomous items is a major challenge in social and behavioral research. Mokken scale analysis (MSA) and exploratory graph analysis (EGA) are approaches for partitioning measures consisting of ...
Gomaa Said Mohamed Abdelhamid, María Dolores Hidalgo, Brian F. French, Juana Gómez-Benito   +3 more
doaj   +1 more source

Kinematic Analysis of 3-SPS/UPR Parallel Worktable

Jixie chuandong, 2022
A worktable of 3-SPS/UPR parallel mechanism is proposed, which is used to assist the less degree of freedom machine tool to process the surface of the workpiece. The kinematic screw matrix of the 3-SPS/UPR parallel mechanism is established; its degree of
Bai Xueqing, Wang Yuan, Li You
doaj  

Organizing the interface—Plasma membrane architecture and receptor dynamics in virus‐cell interactions

FEBS Letters, EarlyView.
Plasma membranes contain dynamic nanoscale domains that organize lipids and receptors. Because viruses operate at similar scales, this architecture shapes early infection steps, including attachment, receptor engagement, and entry. Using influenza A virus and HIV‐1 as examples, we highlight how receptor nanoclusters, multivalent glycan interactions ...
Jan Schlegel, Christian Sieben
wiley   +1 more source

The Use of Voice Control in 3D Medical Data Visualization Implementation, Legal, and Ethical Issues

Information
Voice-controlled devices are becoming increasingly common in our everyday lives as well as in medicine. Whether it is our smartphones, with voice assistants that make it easier to access functions, or IoT (Internet of Things) devices that let us control ...
Miklos Vincze, Bela Molnar, Miklos Kozlovszky   +2 more
doaj   +1 more source