Results 61 to 70 of about 841,230 (289)

Disordered but rhythmic—the role of intrinsic protein disorder in eukaryotic circadian timing

open access: yesFEBS Letters, EarlyView.
Unstructured domains known as intrinsically disordered regions (IDRs) are present in nearly every part of the eukaryotic core circadian oscillator. IDRs enable many diverse inter‐ and intramolecular interactions that support clock function. IDR conformations are highly tunable by post‐translational modifications and environmental conditions, which ...
Emery T. Usher, Jacqueline F. Pelham
wiley   +1 more source

On Numerical methods for determination of Earth gravity field model using mass satellite gravity gradiometry data

open access: yesGeodesy and Geodynamics, 2012
On the basis of Space-Wise Least Square method, three numerical methods including Cholesky decomposition, pre-conditioned conjugate gradient and Open Multi-Processing parallel algorithm are applied into the determination of gravity field with satellite ...
Zhu Guangbin   +4 more
doaj   +1 more source

Protein pyrophosphorylation by inositol pyrophosphates — detection, function, and regulation

open access: yesFEBS Letters, EarlyView.
Protein pyrophosphorylation is an unusual signaling mechanism that was discovered two decades ago. It can be driven by inositol pyrophosphate messengers and influences various cellular processes. Herein, we summarize the research progress and challenges of this field, covering pathways found to be regulated by this posttranslational modification as ...
Sarah Lampe   +3 more
wiley   +1 more source

DEVELOPMENT OF A CORE THERMO-FLUID ANALYSIS CODE FOR PRISMATIC GAS COOLED REACTORS

open access: yesNuclear Engineering and Technology, 2014
A new computer code, named CORONA (Core Reliable Optimization and thermo-fluid Network Analysis), was developed for the core thermo-fluid analysis of a prismatic gas cooled reactor.
NAM-IL TAK   +4 more
doaj   +1 more source

Substrate specificity of Burkholderia pseudomallei multidrug transporters is influenced by the hydrophilic patch in the substrate‐binding pocket

open access: yesFEBS Letters, EarlyView.
Multidrug transporters BpeB and BpeF from the Gram‐negative pathogen Burkholderia pseudomallei have a hydrophilic patch in their substrate‐binding pocket. Drug susceptibility tests and growth curve analyses using an Escherichia coli recombinant expression system revealed that the hydrophilic patches of BpeB and BpeF are involved in the substrate ...
Ui Okada, Satoshi Murakami
wiley   +1 more source

Computing Tropical Prevarieties in Parallel

open access: yes, 2017
The computation of the tropical prevariety is the first step in the application of polyhedral methods to compute positive dimensional solution sets of polynomial systems.
Jensen, Anders   +2 more
core   +1 more source

Mechanisms of parasite‐mediated disruption of brain vessels

open access: yesFEBS Letters, EarlyView.
Parasites can affect the blood vessels of the brain, often causing serious neurological problems. This review explains how different parasites interact with and disrupt these vessels, what this means for brain health, and why these processes matter. Understanding these mechanisms may help us develop better ways to prevent or treat brain infections in ...
Leonor Loira   +3 more
wiley   +1 more source

Structured Parallel Programming: patterns for efficient computation.

open access: yesJournal of Computer Science and Technology, 2015
In this book the authors, who are parallel computing experts and industry insiders, describe how to design and implement maintainable and efficient parallel algorithms using a pattern-based approach.
Armando Eduardo De Giusti
doaj  

Parallel calculations by automata on direct and back spanning trees of a graph

open access: yesТруды Института системного программирования РАН, 2018
The paper presents a parallel computation algorithm of an arbitrary function value on a multiset of values distributed on directed graph vertices. The computation is performed by message passing executed by automata distributed on the graph vertices. The
Igor Burdonov   +2 more
doaj   +1 more source

Time after time – circadian clocks through the lens of oscillator theory

open access: yesFEBS Letters, EarlyView.
Oscillator theory bridges physics and circadian biology. Damped oscillators require external drivers, while limit cycles emerge from delayed feedback and nonlinearities. Coupling enables tissue‐level coherence, and entrainment aligns internal clocks with environmental cues.
Marta del Olmo   +2 more
wiley   +1 more source

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