Results 91 to 100 of about 4,199,345 (361)
preCICE v2: A sustainable and user-friendly coupling library [version 1; peer review: 2 approved]
Open Research Europe, 2022 preCICE is a free/open-source coupling library. It enables creating partitioned multi-physics simulations by gluing together separate software packages. This paper summarizes the development efforts in preCICE of the past five years.
Oguz Ziya Koseomur +19 more
doaj
Genomics‐led approach to drug testing in models of undifferentiated pleomorphic sarcoma
Molecular Oncology, EarlyView.GA text Genomic data from undifferentiated pleomorphic sarcoma patients and preclinical models were used to inform a targeted drug screen. Selected compounds were tested in 2D and 3D cultures of UPS cell lines. A combination of trametinib and infigratinib was synergistic in the majority of UPS cell lines tested, which was further confirmed in an ex ...
Piotr J. Manasterski +19 more
wiley +1 more source
The GlycoPaSER prototype as a real-time N-glycopeptide identification tool based on the PaSER parallel computing platform [PDF]
Int J Mol Sci, 2023 Armony G +9 more
europepmc +2 more sources
A nucleotide‐independent, pan‐RAS‐targeted DARPin elicits anti‐tumor activity in a multimodal manner
Molecular Oncology, EarlyView.We report a Designed Ankyrin Repeat Protein that binds and inhibits RAS proteins, which serve as central cell signaling hubs and are essential for the progression of many cancers. Its unique feature is that it does not discriminate between different RAS isoforms or mutations and is capable of binding to RAS in both its active (GTP‐bound) and inactive ...
Jonas N. Kapp +13 more
wiley +1 more source
High-Performance 3D Compressive Sensing MRI Reconstruction Using Many-Core Architectures
International Journal of Biomedical Imaging, 2011 Compressive sensing (CS) describes how sparse signals can be accurately reconstructed from many fewer samples than required by the Nyquist criterion.
Daehyun Kim +5 more
doaj +1 more source
Molecular Oncology, EarlyView.A DIA‐MS‐based proteomics analysis of serum samples from GB patients and healthy controls showed that high levels of IL1R2 and low levels of CRTAC1 and HRG in serum are associated with poor survival outcomes for GB patients. These circulating proteins could serve as biomarkers for the prediction of outcome in patients with GB.
Anne Clavreul +11 more
wiley +1 more source
FEniCS–preCICE: Coupling FEniCS to other simulation software
SoftwareX, 2021 The new software FEniCS–preCICE is a middle software layer, sitting in between the existing finite-element library FEniCS and the coupling library preCICE.
Benjamin Rodenberg +4 more
doaj
Arrows for Parallel Computation
, 2018 43 pages, 31 main figures, 3 tables, to be submitted to ...
Braun, Martin +2 more
openaire +2 more sources
Molecular Oncology, EarlyView.Non‐small cell lung cancer targeted treatment is limited to a few known genetic alterations, with few alternatives in advanced treatment lines. To direct treatment decisions by drug sensitivity testing (DST), this study compared several methods for tumor cell isolation from malignant effusions, pointing to repeated CD45+ cell depletion for effective ...
Navit Mooshayef +10 more
wiley +1 more source
preCICE v2: A sustainable and user-friendly coupling library [version 2; peer review: 2 approved]
Open Research Europe, 2022 preCICE is a free/open-source coupling library. It enables creating partitioned multi-physics simulations by gluing together separate software packages. This paper summarizes the development efforts in preCICE of the past five years.
Oguz Ziya Koseomur +19 more
doaj