Results 161 to 170 of about 5,818,471 (412)

Adenosine A3 receptor antagonists as anti‐tumor treatment in human prostate cancer: an in vitro study

open access: yesFEBS Open Bio, EarlyView.
The A3 adenosine receptors (A3ARs) are overexpressed in prostate cancer. AR 292 and AR 357, as A3AR antagonists, are capable of blocking proliferation, modulating the expression of drug transporter genes involved in chemoresistance, ferroptosis, and the hypoxia response, and inducing cell death.
Maria Beatrice Morelli   +15 more
wiley   +1 more source

What is Quantum Parallelism, Anyhow? [PDF]

open access: yesarXiv
Central to the power of quantum computing is the concept of quantum parallelism: quantum systems can explore and process multiple computational paths simultaneously. In this paper, we discuss the elusive nature of quantum parallelism, drawing parallels with classical parallel computing models to elucidate its fundamental characteristics and ...
arxiv  

Parallel Computation in Econometrics: A Simplified Approach [PDF]

open access: yes
Parallel computation has a long history in econometric computing, but is not at all wide spread. We believe that a major impediment is the labour cost of coding for parallel architectures.
David F. Hendry   +2 more
core  

Enhanced discovery of bacterial laccase‐like multicopper oxidase through computer simulation and metagenomic analysis of industrial wastewater

open access: yesFEBS Open Bio, EarlyView.
We obtained potential bacterial laccase‐like multicopper oxidase (LMCO) sequences through metagenomic sequencing. All sequences exhibited significant differences from known LMCOs in databases. To select the most promising candidates, we performed structure prediction and molecular docking using alphafold2, metal3d and rosetta.
Ting Cui   +5 more
wiley   +1 more source

Robustness of signal detection in cryo-electron microscopy via a bi-objective-function approach

open access: yesBMC Bioinformatics, 2019
Background The detection of weak signals and selection of single particles from low-contrast micrographs of frozen hydrated biomolecules by cryo-electron microscopy (cryo-EM) represents a major practical bottleneck in cryo-EM data analysis.
Wei Li Wang   +4 more
doaj   +1 more source

Iron‐dependent lysosomal LDL oxidation induces the expression of scavenger receptor A in human THP‐1 monocytes

open access: yesFEBS Open Bio, EarlyView.
In human monocytic cells THP‐1, a limited uptake of native—not oxidized—LDL/VLDL induced expression of scavenger receptor A and cellular adhesion. Induction was inhibited by lysosomotropic (WR‐1065) and lipophilic (BHT) antioxidants and by siRNAs against ferritinophagy.
Martina Čierna   +4 more
wiley   +1 more source

Analysis and Solutions to 3G Gateway Issues in Agriculture WSNs

open access: yesInternational Journal of Distributed Sensor Networks, 2015
Wireless sensor networks (WSN) are used extensively in various important areas of agriculture. Many of the associated activities involve the transmission of data or control commands through gateways that connect the servers to 3G networks. In this paper,
Zhihui Ge, Wei Liu, Tao Shen Li, Jin Ye
doaj   +1 more source

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