Results 141 to 150 of about 4,923,689 (361)

Longitudinal circulating tumor DNA profiling in patients with advanced endometrial cancer using an off‐the‐shelf targeted NGS panel

Molecular Oncology, EarlyView.
Intratumour heterogeneity complicates precision management of advanced endometrial cancer. Circulating tumor DNA (ctDNA) offers a minimally invasive strategy to capture tumor evolution and therapeutic resistance. Here, we compare tumor‐agnostic NGS with tumor‐informed ddPCR, outlining their relative sensitivity, concordance, and clinical implications ...
Carlos Casas‐Arozamena, Karin Teien Lande, Eva Diaz, Ana Vilar, Juan Cueva, Efigenia Arias, Victoria Sampayo, Alicia Abalo, Nerea González, Eva Colás, Antonio Gil‐Moreno, Miguel Abal, Gema Moreno‐Bueno, Therese Sørlie, Kristina Lindemann, Laura Muinelo‐Romay   +15 more
wiley   +1 more source

Simultaneously Estimating Process Variation Effect, Work Function Fluctuation, and Random Dopant Fluctuation of Gate-All-Around Silicon Nanosheet Complementary Field-Effect Transistors

Nanomaterials
We systematically investigate the combined impact of process variation effects (PVEs), metal gate work function fluctuation (WKF), and random dopant fluctuation (RDF) on the key electrical characteristics of sub-1-nm technology node gate-all-around ...
Sekhar Reddy Kola, Yiming Li
doaj   +1 more source

Interpreting the effects of DNA polymerase variants at the structural level

Molecular Oncology, EarlyView.
Using MAVISp and molecular dynamics simulations, we analyzed over 60 000 missense variants in POLE and POLD1 from ClinVar, COSMIC, cBioPortal, and saturation mutagenesis. Identified mechanistic indicators, including stability, binding, and long‐range, enable structural interpretation, providing ACMG‐like evidence for possible reclassification of VUS ...
Matteo Arnaudi, Karolina Krzesińska, Ludovica Beltrame, Pablo Sánchez‐Izquierdo Besora, Matteo Tiberti, Mef Nilbert, Anna Rohlin, Elena Papaleo   +7 more
wiley   +1 more source

Analysis and Solutions to 3G Gateway Issues in Agriculture WSNs

International Journal of Distributed Sensor Networks, 2015
Wireless sensor networks (WSN) are used extensively in various important areas of agriculture. Many of the associated activities involve the transmission of data or control commands through gateways that connect the servers to 3G networks. In this paper,
Zhihui Ge, Wei Liu, Tao Shen Li, Jin Ye
doaj   +1 more source

A low-cost Java-based parallel computing platform for integrated measurement and data processing

, 2000
This paper reports an investigation into the feasibility of utilizing a low-cost Java-based parallel computing platform for measurement and data processing purposes.
Engel, C., Eren, H., Fung, C.C.
core  

Parallel computing: technology trends Advances in parallel computing ;, v. 36./ edited by Ian Foster (Argonne National Laboratory and University of Chicago, Chicago, USA), Gerhard R. Joubert (Technical University Clausthal, Clausthal-Zellerfeld, Germany), Luděk Kučera (Charles University, Prague, Czech Republic), Wolfgang E. Nagel (Technical University Dresden, Dresden, Germany) and Frans Peters (formerly Philips Research, Eindhoven, Netherlands).

, 2020
Conference: "ParCo2019, held in Prague, Czech Republic, from 10-13 September 2019, ..."--Back cover.Includes bibliographical references and indexes.Intro -- Title Page -- Preface -- Conference Organisation -- Contents -- Opening -- Four Decades of ...
Joubert G. R., Kučera Luděk, Foster Ian, Nagel Wolfgang E.,, Peters F. J.,   +4 more
core  

Circulating tumor cell viability during and after radiotherapy mirrors treatment response in cancer patients

Molecular Oncology, EarlyView.
Radiotherapy (RT) response depends on the DNA repair capacity of tumor and host cells. We show that circulating tumor cell (CTC) counts and apoptosis rates before and after RT predict treatment response and outcome, which can be accessed via easily accessible liquid biopsy approaches. Created in BioRender. Wikman, H.
Yvonne Goy, Jana Löptien, Cornelia Coith, Afroditi Nanou, Katharina Hintelmann, Pinnschmidt Hans, Cordula Petersen, Klaus Pantel, Sabine Riethdorf, Kerstin Borgmann, Harriet Wikman   +10 more
wiley   +1 more source

Electrolyte-Gated Vertical Synapse Array based on Van Der Waals Heterostructure for Parallel Computing. [PDF]

Adv Sci (Weinh), 2022
Oh S, Lee JH, Seo S, Choo H, Lee D, Cho JI, Park JH.   +6 more
europepmc   +1 more source

Stimulator of interferon genes agonist augmented antitumor immunity of osimertinib in Egfr‐mutated lung cancer

Molecular Oncology, EarlyView.
Combining osimertinib with the STING agonist ADU‐S100 activates innate and adaptive immunity to overcome the non‐inflamed microenvironment of Egfr‐mutant lung cancer. This combination increases NK and CD8+ T‐cell infiltration, associated with activation of the STING‐IRF3 pathway and local immunogenic cell death.
Jun Nishimura, Tadahiro Kuribayashi, Johannes Brägelmann, Sachi Okawa, Masataka Taoka, Shunta Mori, Tomoka Nishimura, Takaaki Tanaka, Go Makimoto, Kiichiro Ninomiya, Kammei Rai, Eiki Ichihara, Ryohei Katayama, Katsuyuki Hotta, Masahiro Tabata, Yosuke Togashi, Yoshinobu Maeda, Martin L. Sos, Katsuyuki Kiura, Kadoaki Ohashi   +19 more
wiley   +1 more source

A single inverse-designed photonic structure that performs parallel computing. [PDF]

Nat Commun, 2021
Camacho M, Edwards B, Engheta N.
europepmc   +1 more source