Results 121 to 130 of about 2,988,978 (309)

Regulation of the lncRNA NEAT1 by p53‐ΔNp63 crosstalk modulates the DNA damage response and therapeutic efficacy in HNSCC

open access: yesMolecular Oncology, EarlyView.
In head and neck squamous cell carcinoma (HNSCC) p53 and p63 exert opposite roles on the transcription regulation of the lncRNA NEAT1. Under basal conditions, p53 levels are low and p63 represses NEAT1 expression. Upon genotoxic stress, p53 is rapidly induced, displacing p63 from the NEAT1 promoter leading to NEAT1 transcriptional activation and ...
Sara De Domenico   +5 more
wiley   +1 more source

Evaluation of a small scale cluster computing system for parallel intelligent techniques applications [PDF]

open access: yes, 2005
A small scale distributed computing system that is able to meet the needs of parallel intelligent techniques for engineering and science applications is reported in this paper.
Myers, D., Li, J.B., Fung, C.C.
core  

Paclitaxel induces NM2‐dependent cellular contraction through GEF‐H1 dissociation from microtubules and RhoA/ROCK activation in cancer cells

open access: yesMolecular Oncology, EarlyView.
Taxanes are widely used chemotherapeutics whose effects on cellular mechanics remain poorly understood. We show that paclitaxel induces rapid cellular contraction by promoting GEF‐H1 dissociation from microtubules and non‐muscle myosin II activation through RhoA/ROCK.
Gloria Asensio‐Juárez   +5 more
wiley   +1 more source

Shared Memory Parallelism (SC '08 Education Program's Workshop on Parallel & Cluster Computing)

open access: yes, 2008
Henry Neeman, Director OU Supercomputing Center for Education & Research University of Oklahoma SC08 Education Program’s Workshop on Parallel & Cluster Computing August 10-16 2008OUTLINE: ----Parallelism ----Shared Memory Parallelism ...
Neeman, Henry
core  

p190A/ARHGAP35 and p190B/ARHGAP5 proteins in endometrial cancer: a novel cancer‐relevant paralog interplay

open access: yesMolecular Oncology, EarlyView.
This study identifies ARHGAP5, in addition to the frequently mutated ARHGAP35, as significantly mutated in endometrial cancer. Mutations in both genes co‐occur and are associated with their correlated downregulation. Functional CRISPR studies show that both paralogs regulate similar pathways, including actin cytoskeleton organization.
Mathilde Pinault   +12 more
wiley   +1 more source

Introduction to parallel computing

open access: yes, 2003
Introduction to Parallel Computing is a complete end-to-end source of information on almost all aspects of parallel computing from introduction to architectures to programming paradigms to algorithms to programming standards.
Grama, Ananth
core  

A low-cost Java-based parallel computing platform for integrated measurement and data processing [PDF]

open access: yes, 2000
This paper reports an investigation into the feasibility of utilizing a low-cost Java-based parallel computing platform for measurement and data processing purposes.
Engel, C., Eren, H., Fung, C.C.
core  

Extracellular matrix remodeling and immune reprogramming drive residual tumor progression of liver cancer after incomplete microwave ablation

open access: yesMolecular Oncology, EarlyView.
Incomplete microwave ablation (iMWA) of liver cancer triggers a biphasic progression in residual tumors. At Day 3, the microenvironment is characterized by acute inflammatory responses and extracellular matrix (ECM) remodeling. By Day 14, a profound shift occurs toward oncogenic signal transduction and immunosuppression, marked by macrophage ...
Yu Liu   +9 more
wiley   +1 more source

Home - About - Disclaimer - Privacy