Results 161 to 170 of about 4,923,689 (361)

Interconnection networks for parallel and distributed computing [PDF]

open access: yes, 2008
Parallel computers are generally either shared-memory machines or distributed- memory machines. There are currently technological limitations on shared-memory architectures and so parallel computers utilizing a large number of processors tend tube ...
Xiang, Yonghong
core  

MITF maintains genome stability in nonmelanocyte lineages

open access: yesMolecular Oncology, EarlyView.
MITF is essential for melanocyte survival and acts as an oncogene in 10%–20% of melanomas. We show that MITF depletion causes genome instability in nonmelanocytic cells, leading to LATS2‐mediated P53 activation, cell cycle arrest, and apoptosis. This study highlights the role of MITF as a genome maintenance factor beyond the melanocyte lineage. Created
Drifa H. Gudmundsdottir   +13 more
wiley   +1 more source

Emerging opportunities and challenges for the future of reservoir computing

open access: yesNature Communications
Reservoir computing originates in the early 2000s, the core idea being to utilize dynamical systems as reservoirs (nonlinear generalizations of standard bases) to adaptively learn spatiotemporal features and hidden patterns in complex time series.
Min Yan   +5 more
semanticscholar   +1 more source

3DMeshNet: A three-dimensional differential neural network for structured mesh generation

open access: yesGraphical Models
Mesh generation is a crucial step in numerical simulations, significantly impacting simulation accuracy and efficiency. However, generating meshes remains time-consuming and requires expensive computational resources.
Jiaming Peng, Xinhai Chen, Jie Liu
doaj   +1 more source

Evaluation of a small scale cluster computing system for parallel intelligent techniques applications

open access: yes, 2005
A small scale distributed computing system that is able to meet the needs of parallel intelligent techniques for engineering and science applications is reported in this paper.
Myers, D., Li, J.B., Fung, C.C.
core  

Speedup for multi-level parallel computing

open access: yes, 2012
This paper studies the speedup for multi-level parallel computing. Two models of parallel speedup are considered, namely, fixed-size speedup and fixed-time speedup.
Tang, Shanjiang   +5 more
core   +1 more source

A novel quinazolinone insulin receptor inhibitor and its synergy with an EGFR inhibitor in glucose‐driven glioblastoma

open access: yesMolecular Oncology, EarlyView.
The novel styrylquinazolinone‐based molecule W1B effectively suppresses glioblastoma by inhibiting IGF1R and EGFR. In high‐glucose microenvironments driving tumor resistance, W1B acts synergistically with the EGFR inhibitor dacomitinib. This combination safely blocks compensatory survival signaling in zebrafish xenograft models. Showcasing promising in
Patryk Rurka   +9 more
wiley   +1 more source

Overview of Parallelism (SC '08 Education Program's Workshop on Parallel & Cluster Computing)

open access: yes, 2008
Dr. Henry Neeman, Director OU Supercomputing Center for Education & Research University of Oklahoma SC08 Education Program’s Workshop on Parallel & Cluster computing August 10-16 2008OUTLINE: ----Parallelism ----The Jigsaw Puzzle Analogy for ...
Neeman, Henry
core  

Patient therapy outcome modeling in cancer organoids is improved by cancer‐associated fibroblasts and organoid assembly convolution

open access: yesMolecular Oncology, EarlyView.
Patient‐derived organoids (PDOs) from pancreatic, colorectal, and gastric cancers were used to evaluate standard and experimental therapies. Incorporating cancer‐associated fibroblasts (CAFs) into organoid cultures improved patient therapy outcome prediction.
Marcin Grochowski   +12 more
wiley   +1 more source

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