Results 191 to 200 of about 4,923,689 (361)

Biomedical Signal Acquisition Using Sensors under the Paradigm of Parallel Computing. [PDF]

Sensors (Basel), 2020
Moreno Escobar JJ, Morales Matamoros O, Tejeida Padilla R, Chanona Hernández L, Posadas Durán JPF, Pérez Martínez AK, Lina Reyes I, Quintana Espinosa H.   +7 more
europepmc   +1 more source

Parallel computing in global optimization

, 2006
Global optimization problems arise in a wide range of real-world problems. They include applications in operations research, engineering, biological sciences, and computer science.
TORALDO, GERARDO, P. M. PARDALOS, M. D'APUZZO, A. MIGDALAS, MARINO, MARINA   +4 more
core  

Large‐scale bidirectional arrayed genetic screens identify OXR1 and EMC4 as modifiers of αSynuclein aggregation

FEBS Open Bio, EarlyView.
Activation of the mitochondrial protein OXR1 increases pSyn129 αSynuclein aggregation by lowering ATP levels and altering mitochondrial membrane potential, particularly in response to MSA‐derived fibrils. In contrast, ablation of the ER protein EMC4 enhances autophagic flux and lysosomal clearance, broadly reducing α‐synuclein aggregates.
Sandesh Neupane, Lea Nikolić, Lorenzo Maraio, Thomas Goiran, Nathan Karpilovsky, Stefano Sellitto, Vangelis Bouris, Jiang‐An Yin, Ronald Melki, Edward A Fon, Adriano Aguzzi, Elena De Cecco   +11 more
wiley   +1 more source

A Parallel Variant of the Gram-Schmidt Process with Reorthogonalization

, 2006
[EN] This work is concerned with the effective parallelization of algorithms for computing an orthonormal basis of a subspace in the context of Krylov-type eigenvalue solvers such as Arnoldi.
Tomás Domínguez, Andrés Enrique, Jose E. Roman, Hernandez, V.   +2 more
core  

YIPFα1A expression is regulated by multilayered molecular mechanisms

FEBS Open Bio, EarlyView.
YIPFα1A, a five‐pass Golgi protein, is regulated at multiple layers. (1) Rare‐codon enrichment drives translation‐coupled mRNA decay. (2) A proximal 3′‐UTR element stabilizes mRNA. (3) A distal 3′‐UTR element included by alternate poly(A) site usage represses translation, which can be overridden by the proximal 3′‐UTR element.
Tokio Takaji, Yurika Nakanishi, Nobuhiro Nakamura   +2 more
wiley   +1 more source

Pyntacle: a parallel computing-enabled framework for large-scale network biology analysis. [PDF]

Gigascience, 2020
Parca L, Truglio M, Biagini T, Castellana S, Petrizzelli F, Capocefalo D, Jordán F, Carella M, Mazza T.   +8 more
europepmc   +1 more source

Multicore Madness (SC '08 Education Program's Workshop on Parallel & Cluster Computing)

, 2008
Dr. Henry Neeman, Director OU Supercomputing Center for Education & Research University of Oklahoma SC08 Education Program’s Workshop on Parallel & Cluster Computing August 10-16 2008OUTLINE: ----The March of Progress ----Multicore/Many-core ...
Neeman, Henry
core  

Identifying transcription factors controlling the basal expression of human MRP4 highlights a substantial role for Sp1

FEBS Open Bio, EarlyView.
The MRP4 transporter exports several drugs and signaling molecules. Here, we identified key promoter elements regulating basal MRP4 expression. Using reporter assays, we defined a conserved region with essential Sp1 and contributory Ets sites, which controlled basal MRP4 expression.
Debora Singer, Angelique Kragl, Katrin Ziems, Juliane Glaubitz, Sophie Grammbauer, Susanne Hildebrandt, Mladen V. Tzvetkov, Gabriele Jedlitschky   +7 more
wiley   +1 more source

Shared Memory Parallelism (SC '08 Education Program's Workshop on Parallel & Cluster Computing)

, 2008
Henry Neeman, Director OU Supercomputing Center for Education & Research University of Oklahoma SC08 Education Program’s Workshop on Parallel & Cluster Computing August 10-16 2008OUTLINE: ----Parallelism ----Shared Memory Parallelism ...
Neeman, Henry
core  

Derivation and characterization of retinal pigment epithelium from urine‐derived iPSCs

FEBS Open Bio, EarlyView.
Age‐related macular degeneration causes vision loss via RPE dysfunction and loss. Traditional iPSC therapies rely on invasive biopsies, limiting scalability. Here, we utilize urine‐derived stem cells as an accessible source to generate u‐iPSCs, successfully differentiated into pigmented RPE. This “Urine‐to‐Retina” platform provides a promising path for
Daniella Beiner, Hainan Zhu, Carol Christine Bosholm, Heuy‐Ching Wang, Tracy Criswell, Anthony Atala, Jian‐Xing Ma, Yuanyuan Zhang   +7 more
wiley   +1 more source