Results 61 to 70 of about 5,818,471 (412)

Identification of novel small molecule inhibitors of ETS transcription factors

FEBS Letters, EarlyView.
ETS transcription factors play an essential role in tumourigenesis and are indispensable for sprouting angiogenesis, a hallmark of cancer, which fuels tumour expansion and dissemination. Thus, targeting ETS transcription factor function could represent an effective, multifaceted strategy to block tumour growth. The evolutionarily conserved E‐Twenty‐Six
Shaima Abdalla, Zary Forghany, Jin Ma, Johan G. Hollander, Ruta Nachane, Karoly Szuhai, Pancras C. W. Hogendoorn, Peter ten Dijke, Dipen Shah, David A. Baker   +9 more
wiley   +1 more source

Enhancing the Performance of E-Mode AlGaN/GaN HEMTs With Recessed Gates Through Low-Damage Neutral Beam Etching and Post-Metallization Annealing

IEEE Open Journal of Nanotechnology, 2023
This study investigated the electrical properties of AlGaN/GaN high-electron-mobility transistors (HEMTs) with varied recess depths under the gate electrode.
Yi-Ho Chen, Daisuke Ohori, Muhammad Aslam, Yao-Jen Lee, Yiming Li, Seiji Samukawa   +5 more
doaj   +1 more source

The Saccharomyces cerevisiae amino acid transporter Lyp1 has a broad substrate spectrum

FEBS Letters, EarlyView.
In Saccharomyces cerevisiae, Yeast Amino acid Transporter family members mediate the import of amino acids, ranging from substrate specialists to generalists. Here, we show that the specialist transporter, Lyp1, has a broader substrate spectrum than previously described, with affinity constants spanning from micromolar to millimolar.
Foteini Karapanagioti, Sebastian Obermaier, Dirk J. Slotboom, Bert Poolman   +3 more
wiley   +1 more source

Simulation study of 14-nm-gate III-V trigate field effect transistor devices with In1−xGaxAs channel capping layer

AIP Advances, 2015
In this work, we study characteristics of 14-nm-gate InGaAs-based trigate MOSFET (metal-oxide-semiconductor field effect transistor) devices with a channel capping layer.
Cheng-Hao Huang, Yiming Li
doaj   +1 more source

A dual-population Constrained Many-Objective Evolutionary Algorithm based on reference point and angle easing strategy [PDF]

PeerJ Computer Science
Constrained many-objective optimization problems (CMaOPs) have gradually emerged in various areas and are significant for this field. These problems often involve intricate Pareto frontiers (PFs) that are both refined and uneven, thereby making their ...
Chen Ji, Linjie Wu, Tianhao Zhao, Xingjuan Cai   +3 more
doaj   +2 more sources

Exploring the Performance of 3-D Nanosheet FET in Inversion and Junctionless Modes: Device and Circuit-Level Analysis and Comparison

IEEE Access, 2023
In this article, the performance of 3-D nanosheet FET (NS-FET) in inversion (INV) and junctionless (JL) modes is demonstrated and compared at both device and circuit levels.
V. Bharath Sreenivasulu, Aruna Kumari Neelam, Sekhar Reddy Kola, Jawar Singh, Yiming Li   +4 more
doaj   +1 more source

A cellular system to study responses to a collision between the transcription complex and a protein‐bound nick in the DNA template

FEBS Letters, EarlyView.
We present the cellular transcription‐coupled Flp‐nick system allowing the introduction of a Top1‐mimicking cleavage complex (Flpcc) at a Flp recognition target site within a controllable LacZ gene. LacZ transcription leads to the collision of RNA polymerase II (RNAPII) with Flpcc, and this causes RNAPII stalling, ubiquitination, and degradation.
Petra Herring, Morten Roedgaard, Camilla Myrup Holst, Helene Christensen, Birgitta R. Knudsen, Lotte Bjergbaek, Anni Hangaard Andersen   +6 more
wiley   +1 more source

Many-objective evolutionary algorithm based on three-way decision

Egyptian Informatics Journal, 2023
In recent years, many-objective optimization problems have been widely used. however, with the increase of the number of objectives, the difficulty of solving increases exponentially, and the imbalance between convergence and diversity becomes more ...
Zhihua Cui, Bingting Li, Zhuoxuan Lan, Yubin Xu   +3 more
doaj  

Numerical Modeling and High-Speed Parallel Computing: New Perspectives on Tomographic Microwave Imaging for Brain Stroke Detection and Monitoring.

, 2017
This article deals with microwave tomography for brain stroke imaging using state-of-the-art numerical modeling and massively parallel computing. Iterative microwave tomographic imaging requires the solution of an inverse problem based on a minimization ...
Pierre-Henri Tournier, M. Bonazzoli, V. Dolean, F. Rapetti, F. Hecht, F. Nataf, Iannis Aliferis, I. E. Kanfoud, C. Migliaccio, M. D. Buhan, M. Darbas, S. Semenov, C. Pichot   +12 more
semanticscholar   +1 more source

Parallel Computing Techniques [PDF]

, 2011
Parallel computing means to divide a job into several tasks and use more than one processor simultaneously to perform these tasks. Assume you have developed a new estimation method for the parameters of a complicated statistical model. After you prove the asymptotic characteristics of the method (for instance, asymptotic distribution of the estimator),
openaire   +2 more sources