Results 51 to 60 of about 2,988,978 (309)

A dual-population Constrained Many-Objective Evolutionary Algorithm based on reference point and angle easing strategy [PDF]

PeerJ Computer Science
Constrained many-objective optimization problems (CMaOPs) have gradually emerged in various areas and are significant for this field. These problems often involve intricate Pareto frontiers (PFs) that are both refined and uneven, thereby making their ...
Chen Ji, Linjie Wu, Tianhao Zhao, Xingjuan Cai   +3 more
doaj   +2 more sources

Association Between Individualized Education for Kidney Replacement Therapy Modality Selection and Peritoneal Dialysis Initiation: A Cross‐Sectional Study

Therapeutic Apheresis and Dialysis, EarlyView.
ABSTRACT Introduction Peritoneal dialysis (PD) is an established home‐based kidney replacement therapy (KRT), but its uptake remains low in Japan. We evaluated whether individualized education in a dedicated outpatient clinic was associated with the initiation of PD.
Yasuko Ito, Ryuichi Yoshimura, Takaki Yamauchi, Yuta Funakoshi, Hirotaka Sonoda, Seiji Kobayashi, Hiroyuki Terawaki, Takafumi Ito   +7 more
wiley   +1 more source

Enteropathogenic E. coli shows delayed attachment and host response in human jejunum organoid‐derived monolayers compared to HeLa cells

FEBS Letters, EarlyView.
Enteropathogenic E. coli (EPEC) infects the human intestinal epithelium, resulting in severe illness and diarrhoea. In this study, we compared the infection of cancer‐derived cell lines with human organoid‐derived models of the small intestine. We observed a delayed in attachment, inflammation and cell death on primary cells, indicating that host ...
Mastura Neyazi, Pilar Samperio Ventayol, Natalie Burkard, Nicolas Schlegel, Carmen Aguilar, Sina Bartfeld   +5 more
wiley   +1 more source

Analysis of the spatial layer discrete cosine transform coefficient distribution and its application to rate model for H.264/SVC encoder

The Journal of Engineering, 2014
Knowledge of the discrete cosine transform coefficient distribution (DCT-DIST) is important for the encoder design. For example, rate control relies on this knowledge to estimate a possible bit rate and then decide proper coding parameters before the ...
Szu-Wei Lee
doaj   +1 more source

Exploring the Performance of 3-D Nanosheet FET in Inversion and Junctionless Modes: Device and Circuit-Level Analysis and Comparison

IEEE Access, 2023
In this article, the performance of 3-D nanosheet FET (NS-FET) in inversion (INV) and junctionless (JL) modes is demonstrated and compared at both device and circuit levels.
V. Bharath Sreenivasulu, Aruna Kumari Neelam, Sekhar Reddy Kola, Jawar Singh, Yiming Li   +4 more
doaj   +1 more source

Highly Parallel Computation [PDF]

Science, 1990
Highly parallel computing architectures are the only means to achieve the computational rates demanded by advanced scientific problems. A decade of research has demonstrated the feasibility of such machines, and current research focuses on which architectures are best suited for particular classes of problems.
Denning, P. J., Tichy, Walter F.
openaire   +2 more sources

Design and analysis strategies for robust microbiome ageing research

FEBS Letters, EarlyView.
The gut microbiome changes with age and associates with age‐related morbidity and mortality, establishing it as a potential biomarker and intervention target for ageing. Realising this potential requires methodological rigour, yet distinguishing biological signals from methodological artefacts remains challenging across cohorts. This review provides an
Mark Olenik, İsmail Güderer, Yi Wang, Tayyaba Alvi, Prasoon Pandey, Handan Melike Dönertaş   +5 more
wiley   +1 more source

Engineering peptides into antibodies—opportunities and strategies for therapeutic innovation

FEBS Letters, EarlyView.
Peptides and antibodies occupy complementary therapeutic niches. Peptides recognize difficult targets in a compact format, while antibodies add specificity, long half‐life, and effector functions. This review examines strategies that merge both modalities—peptide grafting into loops, terminal and Fc fusions, and bioconjugation—highlighting how ...
Jinling Wang, Ruslana Romaniuk, Hristo L. Svilenov   +2 more
wiley   +1 more source

Space exploration using parallel orbits:A study in parallel symbolic computing [PDF]

, 2013
Orbit enumerations represent an important class of mathematical algorithms which is widely used in computational discrete mathematics. In this paper, we present a new shared-memory implementation of a generic Orbit skeleton in the GAP computer algebra ...
Brown, Christopher Mark, Janjic, Vladimir; id_orcid, Janjic, Vladimir, Loidl, Hans Wolfgang; id_orcid, Linton, Stephen Alexander, Neunhoeffer, Max, Brown, Christopher, Neunhöffer, Max, Loidl, Hans Wolfgang, Linton, Steve, Hammond, Kevin, Loidl, Hans-Wolfgang, Brown, Christopher Mark; id_orcid   +12 more
core   +1 more source

Emerging experimental and computational methods for studying redox‐regulated structural transitions

FEBS Letters, EarlyView.
Redox reactions can reshape proteins and alter how they behave in cells, with important consequences for health and disease. This review explores emerging experimental and computational approaches for discovering these redox‐sensitive protein switches, revealing their structural effects, and predicting their behavior, opening new opportunities to ...
Tasneem Rass, Dana Reichmann, Gábor Erdős   +2 more
wiley   +1 more source