Results 121 to 130 of about 2,240,949 (295)

ZBTB18 Dysfunction Promotes Neuropathic Pain via CHD4‐based Epigenetic Disinhibition of CLIC1 Channels in Sensory Neurons

open access: yesAdvanced Science, EarlyView.
In this study, we identify a novel functional role of ZBTB18 in regulating trigeminal‐mediated neuropathic pain. Nerve injury reduces ZBTB18 in trigeminal ganglion neurons, impairing CHD4/NuRD recruitment and de‐repressing Clic1. Elevated CLIC1 enhances chloride channel activity and neuronal hyperexcitability, thereby driving pain.
Shoupeng Wang   +11 more
wiley   +1 more source

FOXP1 Knockdown Reprograms Th9 CAR‐T Cells to Overcome Antigen Escape

open access: yesAdvanced Science, EarlyView.
FOXP1 knockdown enhances Th9 CAR‐T cell function by promoting IL‐9 production, effector activation, and reduced exhaustion. Reprogrammed Th9 CAR‐T cells strengthen direct tumor killing and activate endogenous antitumor immunity through dendritic cells and CD8+ T cells, thereby suppressing both antigen‐positive and antigen‐loss tumor growth and ...
Yihan Zhu   +14 more
wiley   +1 more source

Tourism English-Croatian Parallel Corpus 2.0

open access: yes, 2016
Sentence aligned parallel corpus built by automatically crawling 25 websites from the tourism ...
Papavassiliou, Vassilis   +7 more
core  

Normalização lexical em traduções de Dom Casmurro, de Machado de Assis: um estudo baseado em corpus [PDF]

open access: yes, 2007
Dissertação (mestrado) - Universidade Federal de Santa Catarina, Centro de Comunicação e Expressão. Programa de Pós-graduação em Estudos da TraduçãoEsta dissertação consiste na investigação da ocorrência do fenômeno da normalização lexical na tradução de
Abreu, Iuri
core  

Parallel corpus EN-SL RSDO4 1.0

open access: yes, 2021
The RSDO4 parallel corpus of English-Slovene and Slovene-English translation pairs was collected as part of work package 4 of the Slovene in the Digital Environment project.
Repar, Andraž, Lebar Bajec, Iztok
core  

Generative AI‐Enabled Discovery and Experimental Demonstration of Ultra‐Broadband Epsilon‐Near‐Zero Perfect Absorbers

open access: yesAdvanced Science, EarlyView.
Researchers developed and applied a generative artificial intelligence (AI) model to optimize epsilon‐near‐zero thin film stacks for ultra‐broadband perfect absorption of light. The fabricated AI‐designed absorber, with a total thickness of only 160 nm, experimentally demonstrated an absorption bandwidth exceeding 1000 nm while maintaining greater than
David Dang   +10 more
wiley   +1 more source

Mechanism‐Informed Language Modeling and Oxygenated 3D Screening Identify Berberine–Enzalutamide Synergy in Prostate Cancer Models

open access: yesAdvanced Science, EarlyView.
By integrating knowledge‐augmented artificial intelligence with an oxygen‐supplemented 3D screening platform, a synergistic interaction between berberine and enzalutamide is identified. The framework integrates compound mechanisms of action with disease‐relevant signaling context to prioritize candidate combinations and generate testable pathway‐based ...
Chih‐Hui Lo   +15 more
wiley   +1 more source

H4K12 Lactylation Impairs Dopaminergic Neuron Energy Metabolism via the HIF‐1α/NDUFS1 Pathway in Parkinson's Disease

open access: yesAdvanced Science, EarlyView.
Lactate and H4K12la are elevated in Parkinson's disease. Mechanistically, p300‐mediated H4K12la enrichment at the HIF‐1α promoter upregulates HIF‐1α, which represses Ndufs1, impairing mitochondrial respiration and energy homeostasis in DA neurons.
Yingyao Liu   +15 more
wiley   +1 more source

Weather Attention in Online Discourse and Price Uncertainty in Agricultural Futures Markets

open access: yesAgribusiness, EarlyView.
ABSTRACT Weather is a central determinant of production risk in agricultural markets, but markets respond not only to weather conditions themselves, but also to how those conditions are noticed, framed, and interpreted in public discourse. In this setting, real‐time online weather discussions may shape price uncertainty by influencing how market ...
Mario A. Ortez   +3 more
wiley   +1 more source

Corpus Bielefeld, Situation de contact, Tandem, RDA

open access: yes, 2010
Interactions privéesInteractions construites, interactions en institutionInteractions entre étudiantes sur les différences entre Allemagne et France">Le corpus a été constitué lors d’un projet « tandem » mené dans le cadre d’un séminaire universitaire à ...
Krafft, Ulrich   +3 more
core   +1 more source

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