Results 71 to 80 of about 329,729 (302)

The (Glg)ABCs of cyanobacteria: modelling of glycogen synthesis and functional divergence of glycogen synthases in Synechocystis sp. PCC 6803

open access: yesFEBS Letters, EarlyView.
We reconstituted Synechocystis glycogen synthesis in vitro from purified enzymes and showed that two GlgA isoenzymes produce glycogen with different architectures: GlgA1 yields denser, highly branched glycogen, whereas GlgA2 synthesizes longer, less‐branched chains.
Kenric Lee   +3 more
wiley   +1 more source

Assembling strategies in extrinsic evolvable hardware with bi-directional incremental evolution

open access: yes, 2003
Bidirectional incremental evolution (BIE) has been proposed as a technique to overcome the ”stalling” effect in evolvable hardware applications. However preliminary results show perceptible dependence of performance of BIE and quality of evaluated ...
Baradavka, I   +3 more
core   +1 more source

Ploidy differences represent an impassable barrier for hybridization. Is there an exception among botiid loaches (Cypriniformes: Botiidae)?

open access: yesFrontiers in Marine Science, 2015
One of the most efficient mechanisms to keep animal lineages separate is a difference in ploidy level, since hybrid offspring from parents with different ploidy level are generally sterile.
Joerg Bohlen
doaj   +1 more source

A biogeographic perspective on the evolution of fire syndromes in pine trees (Pinus: Pinaceae) [PDF]

open access: yesRoyal Society Open Science, 2018
Our goals were to explore the relationship between biogeography and the evolution of fire-adaptive syndromes in the genus Pinus. We used a previously published time-calibrated phylogeny and conducted ancestral trait reconstruction to estimate the likely ...
Kevin J. Badik   +2 more
doaj   +1 more source

Organ‐specific redox imbalances in spinal muscular atrophy mice are partially rescued by SMN antisense oligonucleotides

open access: yesFEBS Letters, EarlyView.
We identified a systemic, progressive loss of protein S‐glutathionylation—detected by nonreducing western blotting—alongside dysregulation of glutathione‐cycle enzymes in both neuronal and peripheral tissues of Taiwanese SMA mice. These alterations were partially rescued by SMN antisense oligonucleotide therapy, revealing persistent redox imbalance as ...
Sofia Vrettou, Brunhilde Wirth
wiley   +1 more source

Evolution of Repetitive Genomic Content and Gene Families Over Geo‐Climatic Gradients in Brassicaceae

open access: yesEcology and Evolution
On temperature gradients such as elevation or latitude, species turnover is common, and specialists can persist in extreme environments. This is likely paralleled by adaptive and possibly also non‐adaptive changes on a molecular level, from genes to the ...
Jana M. Flury   +3 more
doaj   +1 more source

Predominance of cis-regulatory changes in parallel expression divergence of sticklebacks

open access: yeseLife, 2019
Regulation of gene expression is thought to play a major role in adaptation, but the relative importance of cis- and trans- regulatory mechanisms in the early stages of adaptive divergence is unclear.
Jukka-Pekka Verta, Felicity C Jones
doaj   +1 more source

A Total Evidence Phylogenetic Analysis of Pinniped Phylogeny and the Possibility of Parallel Evolution Within a Monophyletic Framework

open access: yesFrontiers in Ecology and Evolution, 2020
In the present study, a series of phylogenetic analyses of morphological, molecular, and combined morphological-molecular datasets were conducted to investigate the relationships of 23 extant and 44 fossil caniforme genera, in order to test the ...
Ryan S. Paterson   +5 more
doaj   +1 more source

Transferrin receptor 1‐mediated iron uptake supports thermogenic activation in human cervical‐derived adipocytes

open access: yesFEBS Letters, EarlyView.
In this study, we found that human cervical‐derived adipocytes maintain intracellular iron level by regulating the expression of iron transport‐related proteins during adrenergic stimulation. Melanotransferrin is predicted to interact with transferrin receptor 1 based on in silico analysis.
Rahaf Alrifai   +9 more
wiley   +1 more source

Contrasting effects of environment and genetics generate a continuum of parallel evolution

open access: yes, 2017
Parallel evolution of similar traits by independent populations in similar environments is considered strong evidence for adaptation by natural selection.
Tania Tasneem   +44 more
core   +1 more source

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