Results 81 to 90 of about 329,729 (302)

Structural insights into an engineered feruloyl esterase with improved MHET degrading properties

FEBS Letters, EarlyView.
A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa, Konstantinos Makryniotis, Theofani‐Iosifina Sousani, Evangelos Topakas, Vangelis Daskalakis, Maria Dimarogona   +5 more
wiley   +1 more source

Many-to-one form-to-function mapping weakens parallel morphological evolution

, 2017
Evolutionary ecologists aim to explain and predict evolutionary change under different selective regimes. Theory suggests that such evolutionary prediction should be more difficult for biomechanical systems in which different trait combinations generate ...
Daniel I. Bolnick, Peichel, Catherine, Hendry, Andrew P, Andrew P. Hendry, Bolnick, Daniel I, Thompson, Cole J, Ahmed, Newaz I, Newaz I. Ahmed, Yoel E. Stuart, Thor Veen, Stuart, Yoel E, Cole J. Thompson, Catherine L. Peichel, Veen, T   +13 more
core   +1 more source

Parallel Evolution of Complex Centipede Venoms Revealed by Comparative Proteotranscriptomic Analyses

, 2022
S.2748-2763Centipedes are among the most ancient groups of venomous predatory arthropods. Extant species belong to five orders, but our understanding of the composition and evolution of centipede venoms is based almost exclusively on one order ...
Jenner, R.A., Campbell, L.I., Reumont, B.M. von, Undheim, E.A.B.   +3 more
core   +1 more source

Developmental bias as a cause and consequence of adaptive radiation and divergence

Frontiers in Cell and Developmental Biology
Efforts to reconcile development and evolution have demonstrated that development is biased, with phenotypic variation being more readily produced in certain directions.
Corin Stansfield, Kevin J. Parsons
doaj   +1 more source

An Example of Parallelism in Carnivore Brain Evolution [PDF]

Evolution, 1971
A survey of the external brain morphology of fossil Carnivora revealed that the cruciate sulcus, a major landmark of the cerebral cortex which is present in all living carnivoran families, did not exist in the common ancestor of those families, and thus evolved independently several times. The history of the carnivoran cruciate sulcus is of interest as
openaire   +2 more sources

Diversity and complexity in neural organoids

FEBS Letters, EarlyView.
Neural organoid research aims to expand genetic diversity on one side and increase tissue complexity on the other. Chimeroids integrate multiple donor genomes within single organoids. Self‐organising multi‐identity organoids, exogenous cell seeding, or enforced assembly of region‐specific organoids contribute to tissue complexity.
Ilaria Chiaradia, Madeline A. Lancaster
wiley   +1 more source

Hyperosmotic stress induces PARP1‐mediated HPF1‐dependent mono(ADP‐ribosyl)ation

FEBS Letters, EarlyView.
Sorbitol‐induced hyperosmotic stress rapidly induces reversible mono(ADP‐ribosyl)ation (MARylation) on PARP1 without the signs of genotoxic signaling. We show that PARP1 autoMARylation is HPF1 dependent and forms hydroxylamine‐resistant O‐glycosidic linkages.
Anna Georgina Kopasz, Mihály Mérey, Rebeka Vásárhelyi, Ramóna Pék, Victor Imburchia, László Henn, Adrián Kószó, Nicholas D. Lakin, Ivan Ahel, Sébastien Huet, Ágnes Czibula, Gyula Timinszky   +11 more
wiley   +1 more source

Parallel and perpendicular cascades in solar wind turbulence

, 2005
MHD-scale fluctuations in the velocity, magnetic, and density fields of the solar wind are routinely observed. The evolution of these fluctuations, as they are transported radially outwards by the solar wind, is believed to involve both wave and ...
Matthaeus, William H., Oughton, Sean, S. Oughton, W. H. Matthaeus, Oughton, S., Matthaeus, W. H.   +5 more
core   +1 more source

Parallel evolution of local adaptation and reproductive isolation in the face of gene flow [PDF]

, 2013
Parallel evolution of similar phenotypes provides strong evidence for the operation of natural selection. Where these phenotypes contribute to reproductive isolation, they further support a role for divergent, habitat-associated selection in speciation ...
Marina Panova, Galindo, Juan, Galindo, J., Saura, M., Humberto Quesada, Benjamin Jackson, Charrier, Grégory, Rolan-Alvarez, Emilio, André, C, Panova, M., Quesada, H, Butlin, RK, André, Carl,, Johannesson, K, Johannesson, Kerstin, Kemppainen, Petri,, Johannesson, Kerstin,, Juan Galindo, Kemppainen, P., Caballero, A., Charrier, G, Grahame, JW, Kemppainen, P, Rolan-Alvarez, E., Quesada, H., Rolán-Alvarez, E, Panova, Marina, Johannesson, K., Caballero, Armando, Jackson, B., Panova, Marina,, Grégory Charrier, Carl André, Andre, Carl, Coyne, JA, Saura, M, Emilio Rolán-Alvarez, Martínez-Fernández, M, John W. Grahame, Martinez-Fernandez, M., Jackson, B, Hollander, Johan, Johan Hollander, Butlin, Roger K., Coyne, J. A., Armando Caballero, Charrier, G., Panova, M, Jackson, Benjamin, Caballero, A, Martinez-Fernandez, Monica, Grahame, John W., Roger K. Butlin, Galindo, J, Quesada, Humberto, Charrier, Grégory,, Saura, Maria, Hollander, J, Kerstin Johannesson, Maria Saura, André, C., Kemppainen, Petri, Butlin, R. K., Grahame, J. W., Petri Kemppainen, Coyne, Jerry A., Mónica Martínez-Fernández, Jerry A. Coyne, Hollander, J., Butlin, Roger,   +69 more
core   +1 more source

Organizing the interface—Plasma membrane architecture and receptor dynamics in virus‐cell interactions

FEBS Letters, EarlyView.
Plasma membranes contain dynamic nanoscale domains that organize lipids and receptors. Because viruses operate at similar scales, this architecture shapes early infection steps, including attachment, receptor engagement, and entry. Using influenza A virus and HIV‐1 as examples, we highlight how receptor nanoclusters, multivalent glycan interactions ...
Jan Schlegel, Christian Sieben
wiley   +1 more source