Results 121 to 130 of about 26,778,061 (298)

Using Horn’s Parallel Analysis Method in Exploratory Factor Analysis for Determining the Number of Factors

Educational Sciences: Theory & Practice, 2016
Psychological characteristics are of an abstract or latent nature rather than a tangible, observable one and they are called constructs or factors (Kline, 2005; Nunnaly & Bernstein, 1994). Constructs are hypothetical concepts and the existence of certain constructs is never absolutely confirmed.
openaire   +2 more sources

IMPDH inhibition enhances cytarabine efficacy in SAMHD1‐expressing leukaemia cells via guanine nucleotide depletion

Molecular Oncology, EarlyView.
Cytarabine is a key therapy for acute myeloid leukaemia (AML), but its efficacy is limited by the dNTPase SAMHD1, which hydrolyses its active metabolite. Screening nucleotide biosynthesis inhibitors revealed that IMPDH inhibitors selectively sensitise SAMHD1‐proficient AML cells to cytarabine.
Miriam Yagüe‐Capilla, Christopher Dirks, Caroline Eiden, Sonja K. Fesenmayer, Femke M. Hormann, Yolande Klootsema, Ingrid Lilienthal, Si Min Zhang, Nikolas Herold, Sean G. Rudd   +9 more
wiley   +1 more source

Development of the Singapore workplace wellbeing scale

Cogent Psychology
The present research described the development of the Singapore Workplace Wellbeing scale which identified the factors that influence employee wellbeing in the Singapore workplace context.
Chad Chew Eun Yip, Tony Machin, Yong Wah Goh   +2 more
doaj   +1 more source

Parallel Factor Analysis Enables Quantification and Identification of Highly Convolved Data-Independent-Acquired Protein Spectra. [PDF]

Patterns (N Y), 2020
Buric F, Zrimec J, Zelezniak A.
europepmc   +1 more source

Transcriptional profiling of circulating extracellular vesicles from prebiopsy prostate cancer patients

Molecular Oncology, EarlyView.
RNA profiling of circulating extracellular vesicles (EVs) from blood samples of men undergoing prostate biopsy identifies transcripts associated with clinically significant prostate cancer. Integrative analysis with public tumor datasets links EV‐derived gene signatures to tumor stage and progression‐free survival, highlighting CASP3, XRCC2, and RIT1 ...
Stefan Werner, Pierre Tennstedt, Randi C. Pose, Christian Müller, Katharina Besler, Svenja Schneegans, Malik Alawi, Marie C. Roesch, Sven Peine, Desiree Bonci, Joanna Budna‐Tukan, Evi Lianidou, Catherine Alix‐Panabières, Derya Tilki, Klaus Pantel   +14 more
wiley   +1 more source

Factor analysis latent subspace modeling and robust fuzzy clustering using t-distributions

, 2009
Factor analysis is a latent subspace model commonly used for local dimensionality reduction tasks. Fuzzy c-means (FCM) type fuzzy clustering approaches are closely related to Gaussian mixture models (GMMs), and expectation - maximization (EM) like ...
Varvarigou, T, Varvarigou, Theodora, Chatzis, S, Chatzis, Sotirios P.   +3 more
core   +1 more source

Metastasis on pause: How dormant tumor cells stay hidden within the tumor microenvironment and evade immune surveillance

Molecular Oncology, EarlyView.
Dormant cancer cells can hide in distant organs for years, evading treatment and the immune system. This review highlights how signals from the surrounding tissue and immune environment keep these cells inactive or trigger their reawakening. Understanding these mechanisms may help develop therapies to eliminate or control dormant cells and prevent ...
Kanishka Tiwary, Jose Javier Bravo‐Cordero   +1 more
wiley   +1 more source

Examining the unidimensionality of the PHQ-9 with first responders: Evidence from different psychometric paradigms

African Journal of Psychological Assessment
The Patient Health Questionnaire-9 (PHQ-9) is an effective tool for identifying depressive disorders in diverse populations, making it a valuable resource in both clinical practice and research.
Tyrone B. Pretorius, Anita Padmanabhanunni   +1 more
doaj   +1 more source

Fluorescence regional integration combined with parallel factor analysis to quantify fluorescencent spectra for dissolved organic matter released from manure biochars. [PDF]

RSC Adv, 2020
Peng N, Wang K, Tu N, Liu Y, Li Z.
europepmc   +1 more source

Stimulator of interferon genes agonist augmented antitumor immunity of osimertinib in Egfr‐mutated lung cancer

Molecular Oncology, EarlyView.
Combining osimertinib with the STING agonist ADU‐S100 activates innate and adaptive immunity to overcome the non‐inflamed microenvironment of Egfr‐mutant lung cancer. This combination increases NK and CD8+ T‐cell infiltration, associated with activation of the STING‐IRF3 pathway and local immunogenic cell death.
Jun Nishimura, Tadahiro Kuribayashi, Johannes Brägelmann, Sachi Okawa, Masataka Taoka, Shunta Mori, Tomoka Nishimura, Takaaki Tanaka, Go Makimoto, Kiichiro Ninomiya, Kammei Rai, Eiki Ichihara, Ryohei Katayama, Katsuyuki Hotta, Masahiro Tabata, Yosuke Togashi, Yoshinobu Maeda, Martin L. Sos, Katsuyuki Kiura, Kadoaki Ohashi   +19 more
wiley   +1 more source