pH‐mediated activation of the lysosomal arginine sensor SLC38A9
FEBS Letters, EarlyView.Cells monitor nutrient levels via the lysosomal transporter SLC38A9 to activate the mechanistic target of rapamycin complex 1 (mTORC1). This study reveals that SLC38A9 function is regulated by pH. We identified histidine 544 as a critical pH sensor that undergoes conformational changes to control amino acid efflux from lysosomes; therefore, it ...
Xuelang Mu, Ampon Sae Her, Tamir Gonen
wiley +1 more source
Passive Localization of 3D Near-Field Cyclostationary Sources Using Parallel Factor Analysis
International Journal of Antennas and Propagation, 2013 By exploiting favorable characteristics of a uniform cross-array, a passive localization algorithm of narrowband cyclostationary sources in the spherical coordinates (azimuth, elevation, and range) is proposed.
Jian Chen, Guohong Liu, Xiaoying Sun
doaj +1 more source
Identification and Quantification of the Main Psychoactive Ingredients of Cannabis in Urine Using Excitation-Eemission Matrix Fluorescence Coupled with Parallel Factor Analysis. [PDF]
ACS Omega, 2023 Cui SF +4 more
europepmc +1 more source
A Lanczos eigenvalue method on a parallel computer [PDF]
Eigenvalue analyses of complex structures is a computationally intensive task which can benefit significantly from new and impending parallel computers.
Bostic, Susan W., Fulton, Robert E.
core +1 more source
The Global Star-Formation Law by Supernova Feedback
, 2019 We address a simple model where the Kennicutt-Schmidt (KS) relation between the macroscopic densities of star-formation rate (SFR, $\rho_{\rm sfr}$) and gas ($n$) in galactic discs emerges from self-regulation of the SFR via supernova feedback. It arises
Bournaud, Frederic +6 more
core +1 more source
Plecstatin inhibits hepatocellular carcinoma tumorigenesis and invasion through cytolinker plectin
Molecular Oncology, EarlyView.The ruthenium‐based metallodrug plecstatin exerts its anticancer effect in hepatocellular carcinoma (HCC) primarily through selective targeting of plectin. By disrupting plectin‐mediated cytoskeletal organization, plecstatin inhibits anchorage‐dependent growth, cell polarization, and tumor cell dissemination.
Zuzana Outla +10 more
wiley +1 more source
How to factor-analyze your data right: do’s, don’ts, and how-to’s.
International Journal of Psychological Research, 2010 The current article provides a guideline for conducting factor analysis, a technique used to estimate the population-level factor structure underlying the given sample data. First, the distinction between exploratory and confirmatory factor analyses (EFA
Masaki Matsunaga
doaj +1 more source
Parallel factor analysis for multidimensional decomposition of functional near-infrared spectroscopy data. [PDF]
Neurophotonics, 2022 Hüsser A +5 more
europepmc +1 more source
Factor structure of the straightforward incivility scale in an Italian sample
, 2015 Workplace incivility is defined as low-intensity deviant behavior with ambiguous intent to harm the target. In this sense, it involves a violation of workplace norms that could damage the quality of working relationships.
Campagna, Marcello +3 more
core +1 more source
Molecular Oncology, EarlyView.Nanosecond infrared laser (NIRL) low‐volume sampling combined with shotgun lipidomics uncovers distinct lipidome alterations in oropharyngeal squamous cell carcinoma (OPSCC) of the palatine tonsil. Several lipid species consistently differentiate tumor from healthy tissue, highlighting their potential as diagnostic markers.
Leonard Kerkhoff +11 more
wiley +1 more source