Results 101 to 110 of about 891,924 (262)

Parallel Factor Analysis Enables Quantification and Identification of Highly Convolved Data-Independent-Acquired Protein Spectra. [PDF]

Patterns (N Y), 2020
Buric F, Zrimec J, Zelezniak A.
europepmc   +1 more source

Autophagy and mitophagy in pancreatic β‐cell homeostasis and their involvement in diabetes pathophysiology

FEBS Letters, EarlyView.
This review focuses on the role of autophagy and mitophagy in maintaining pancreatic β‐cell function and homeostasis. We discuss how genetic defects affecting these pathways contribute to the development of type 1, type 2, monogenic, and gestational diabetes. We further explore their potential as therapeutic targets. Created in BioRender.
Yunkyeong Lee, Mingming Tong, Anna L. Gloyn   +2 more
wiley   +1 more source

Examining the unidimensionality of the PHQ-9 with first responders: Evidence from different psychometric paradigms

African Journal of Psychological Assessment
The Patient Health Questionnaire-9 (PHQ-9) is an effective tool for identifying depressive disorders in diverse populations, making it a valuable resource in both clinical practice and research.
Tyrone B. Pretorius, Anita Padmanabhanunni   +1 more
doaj   +1 more source

The role of miR‐335‐5p in the redifferentiation of BRAF p.V600E thyroid cancers

Molecular Oncology, EarlyView.
The BRAF p.V600E mutation promotes thyroid cancer dedifferentiation and radioiodine resistance. Using a network approach, we identified miR‐335‐5p as a key regulator of BRAF‐mutated thyroid tumors. Restoring miR‐335‐5p increased thyroid‐specific gene expression and iodine uptake in cells and organoids.
Valeria Pecce, Simone Bini, Marialuisa Sponziello, Giorgio Grani, Giulia Fiscon, Paola Paci, Lorenzo Farina, Rosa Falcone, Valentina Maggisano, Sebastiano Filetti, Cosimo Durante, Antonella Verrienti   +11 more
wiley   +1 more source

Fluorescence regional integration combined with parallel factor analysis to quantify fluorescencent spectra for dissolved organic matter released from manure biochars. [PDF]

RSC Adv, 2020
Peng N, Wang K, Tu N, Liu Y, Li Z.
europepmc   +1 more source

Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment

Molecular Oncology, EarlyView.
This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley   +1 more source

Comparison of Factor Retention Methods in Exploratory Factor Analysis: RMSEA, Root Deterioration per Restriction and Parallel Analysis

SAGE Open
The primary goal of exploratory factor analysis (EFA) is to determine the number of factors and their structure. Thus, the decision on the number of factors to retain is crucial.
Sangyoug Bae, Sehee Hong
doaj   +1 more source

A Comparison of Methods for Determining the Number of Factors to Retain in Exploratory Factor Analysis for Categorical Indicator Variables

Psychology International
Exploratory factor analysis (EFA) is a widely used tool in the social sciences. Researchers employ it to identify the latent structure underlying observed indicator variables during the process of scale development, theory construction, and comparison of
Holmes Finch
doaj   +1 more source

Assessing the chemical compositions and disinfection byproduct formation of biofilms: Application of fluorescence excitation-emission spectroscopy coupled with parallel factor analysis. [PDF]

Chemosphere, 2020
Li L, Jeon Y, Ryu H, Santo Domingo JW, Seo Y.   +4 more
europepmc   +1 more source

Dimethyl fumarate combined with cisplatin at subcytotoxic doses sensitizes cervical cancer toward ferroptosis and apoptosis through GSH restriction and p53 (re)activation

Molecular Oncology, EarlyView.
Dimethyl fumarate (DMF) reduces growth of HPV‐positive cervical cancer spheroids and induces ferroptosis in cervical cancer cells via blocking SLC7A11/Glutathione (GSH) axis. Combination of subcytotoxic doses of DMF and cisplatin (CDDP) further suppresses spheroid growth and drives cell death in 2D culture models.
Carolina Punziano, Giuseppina Minopoli, Simona Romano, Laura Marrone, Katia Aquilano, Maria Lina Tornesello, Raffaella Faraonio   +6 more
wiley   +1 more source