Results 91 to 100 of about 26,778,061 (298)

Liver organoids: modelling complexity in homeostasis and disease

FEBS Letters, EarlyView.
Studying liver in vitro has been challenging because simple 2D cell cultures fail to capture liver's cellular and architectural complexity. To bridge this gap, scientists increasingly use organoids, 3D liver models which better mimic liver composition and function. This review examines recent advances in liver organoid complexity and realism, discusses
Anna M. Dowbaj, Meritxell Huch
wiley   +1 more source

Identification and Quantification of the Main Psychoactive Ingredients of Cannabis in Urine Using Excitation-Eemission Matrix Fluorescence Coupled with Parallel Factor Analysis. [PDF]

ACS Omega, 2023
Cui SF, Yang HL, Lin SY, Wan JW, Zhou CH.   +4 more
europepmc   +1 more source

The microbiome in human skin aging

FEBS Letters, EarlyView.
Age‐related skin changes encompass the well‐known visible phenotypic alterations, together with microbiome dysbiosis and a series of molecular aging hallmarks. These hallmarks characterize not only a fully stablished aged phenotype but also the skin aging process itself.
Manuel Huerta Arana, Cornelia Wiegand, Omid Omrani, Mario Fabri   +3 more
wiley   +1 more source

Characterisation based bottleneck analysis of parallel systems [PDF]

Bottleneck analysis plays an important role in the early design of parallel computers and programs. In this paper a methodology for bottleneck analysis based on an instruction level characterisation technique is presented. The methodology is based on the
Nudd, G. R., Zemerly, M. J., Papay, J.
core  

Ubiquitin Chain Analysis by Parallel Reaction Monitoring.

, 2020
peer reviewedAssessment of the global profile of ubiquitin chain topologies within a proteome is of interest to answer a wide range of biological questions.
LONGWORTH, Joseph, Mendes, Marta L, DITTMAR, Gunnar   +2 more
core   +1 more source

Parallel factor analysis for multidimensional decomposition of functional near-infrared spectroscopy data. [PDF]

Neurophotonics, 2022
Hüsser A, Caron-Desrochers L, Tremblay J, Vannasing P, Martínez-Montes E, Gallagher A.   +5 more
europepmc   +1 more source

Autophagy and mitophagy in pancreatic β‐cell homeostasis and their involvement in diabetes pathophysiology

FEBS Letters, EarlyView.
This review focuses on the role of autophagy and mitophagy in maintaining pancreatic β‐cell function and homeostasis. We discuss how genetic defects affecting these pathways contribute to the development of type 1, type 2, monogenic, and gestational diabetes. We further explore their potential as therapeutic targets. Created in BioRender.
Yunkyeong Lee, Mingming Tong, Anna L. Gloyn   +2 more
wiley   +1 more source

Characterizing Soil Dissolved Organic Matter Across a Permafrost Thaw Gradient (Continuous to Isolated Patches) in Northeastern China

Ecology and Evolution
Permafrost zones are currently experiencing rapid warming, and dissolved organic matter (DOM) is a potentially important pathway for carbon release from permafrost after thawing.
Siyuan Zou, Xiaodong Wu, Jiawei Zhang, Nannan Zhang, Xiangwen Wu, Shuying Zang   +5 more
doaj   +1 more source

Factor structure of the depression anxiety stress Scale-21 (DASS-21): Unidimensionality of the Arabic version among Egyptian drug users

Substance Abuse Treatment, Prevention, and Policy, 2019
Background Emotional distress is common among illicit drug users, and it can negatively affect treatment outcomes and increase the risk of relapse. Nonetheless, instruments that properly measure emotional distress are lacking.
Amira Mohammed Ali, Joseph Green
doaj   +1 more source

Fluorescent spectroscopy paired with parallel factor analysis for quantitative monitoring of phenanthrene biodegradation and metabolite formation. [PDF]

Chemosphere, 2023
Huizenga JM, Semprini L.
europepmc   +1 more source