Results 71 to 80 of about 891,924 (262)

Hyperosmotic stress induces PARP1‐mediated HPF1‐dependent mono(ADP‐ribosyl)ation

open access: yesFEBS Letters, EarlyView.
Sorbitol‐induced hyperosmotic stress rapidly induces reversible mono(ADP‐ribosyl)ation (MARylation) on PARP1 without the signs of genotoxic signaling. We show that PARP1 autoMARylation is HPF1 dependent and forms hydroxylamine‐resistant O‐glycosidic linkages.
Anna Georgina Kopasz   +11 more
wiley   +1 more source

Fast Decomposition of Single Excitation–Emission Matrix Fluorescence Spectrum via Encoder–Decoder Model

open access: yesPhotonics
Three–dimensional excitation–emission matrix (3D–EEM) fluorescence spectroscopy is widely applied for the rapid characterization of dissolved organic matter (DOM) in aquatic environments.
Zhenjie Zhou, Qingtao Wu, Xiaoping Wang
doaj   +1 more source

An isoform of 14‐3‐3 protein regulates transbilayer lipid movement at the plasma membrane

open access: yesFEBS Letters, EarlyView.
Loss of 14‐3‐3ζ in CHO cells confers resistance to exogenous phosphatidylserine (PS) and impairs endocytosis‐independent inward flip‐flop of fluorescent PS at the plasma membrane. RNAi‐mediated knockdown reproduces this defect, while no additive effect is seen in ATP11C‐deficient cells.
Akiko Yamaji‐Hasegawa   +3 more
wiley   +1 more source

Organizing the interface—Plasma membrane architecture and receptor dynamics in virus‐cell interactions

open access: yesFEBS Letters, EarlyView.
Plasma membranes contain dynamic nanoscale domains that organize lipids and receptors. Because viruses operate at similar scales, this architecture shapes early infection steps, including attachment, receptor engagement, and entry. Using influenza A virus and HIV‐1 as examples, we highlight how receptor nanoclusters, multivalent glycan interactions ...
Jan Schlegel, Christian Sieben
wiley   +1 more source

Septin 9 PB domains coordinate centrosome positioning and microtubule acetylation to control epithelial polarity

open access: yesFEBS Letters, EarlyView.
Septin 9 polybasic domains couple phosphoinositide‐rich membrane binding to centrosome positioning, Golgi organization, and microtubule acetylation to control epithelial polarity. Their loss disrupts this axis, causing centrosome mispositioning, Golgi fragmentation, reduced microtubule acetylation, and polarity inversion via upregulation of the ...
Ting ting Cai   +4 more
wiley   +1 more source

Characterizing Soil Dissolved Organic Matter Across a Permafrost Thaw Gradient (Continuous to Isolated Patches) in Northeastern China

open access: yesEcology and Evolution
Permafrost zones are currently experiencing rapid warming, and dissolved organic matter (DOM) is a potentially important pathway for carbon release from permafrost after thawing.
Siyuan Zou   +5 more
doaj   +1 more source

A novel time–frequency–space method with parallel factor theory for big data analysis in condition monitoring of complex system

open access: yesInternational Journal of Advanced Robotic Systems, 2020
The spatial information of the signal is neglected by the conventional frequency/time decompositions such as the fast Fourier transformation, principal component analysis, and independent component analysis. Framing of the data being as a three-way array
Liu Yang   +6 more
doaj   +1 more source

Parallel factor analysis for multidimensional decomposition of functional near-infrared spectroscopy data. [PDF]

open access: yesNeurophotonics, 2022
Hüsser A   +5 more
europepmc   +1 more source

Microbiome−host proteostasis crosstalk—An emerging perspective on mechanisms and interventions toward healthy longevity

open access: yesFEBS Letters, EarlyView.
Proteostasis and the gut microbiota play a key role in shaping host physiology. Microbiota‐derived metabolites, vitamins, and RNA modulate host proteostasis. Findings from model systems, including C. elegans, indicate microbes can either stabilize or disrupt host proteostasis.
Abhishek Anil Dubey, Maria Ermolaeva
wiley   +1 more source

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