Results 71 to 80 of about 2,891,505 (287)

Cell wall target fragment discovery using a low‐cost, minimal fragment library

FEBS Letters, EarlyView.
LoCoFrag100 is a fragment library made up of 100 different compounds. Similarity between the fragments is minimized and 10 different fragments are mixed into a single cocktail, which is soaked to protein crystals. These crystals are analysed by X‐ray crystallography, revealing the binding modes of the bound fragment ligands.
Kaizhou Yan, Mathew Stanley, Olawale Raimi, Andrew T. Ferenbach, Helge C Dorfmueller, Daan M. F. van Aalten   +5 more
wiley   +1 more source

The (Glg)ABCs of cyanobacteria: modelling of glycogen synthesis and functional divergence of glycogen synthases in Synechocystis sp. PCC 6803

FEBS Letters, EarlyView.
We reconstituted Synechocystis glycogen synthesis in vitro from purified enzymes and showed that two GlgA isoenzymes produce glycogen with different architectures: GlgA1 yields denser, highly branched glycogen, whereas GlgA2 synthesizes longer, less‐branched chains.
Kenric Lee, Dimitrios Bekiari, Sofia Doello, Karl Forchhammer   +3 more
wiley   +1 more source

The Influence of Pyrolysis Temperature and Feedstocks on the Characteristics of Biochar-Derived Dissolved Organic Matter: A Systematic Assessment

Clean Technologies
Biochar is a carbon-rich product obtained by pyrolyzing biomass under oxygen-limited conditions and has a wide range of potential for environmental applications.
Yaru Li, Weipeng Chen, Shu Fang, Zhihua Xu, Haifeng Weng, Xiaodong Zhang   +5 more
doaj   +1 more source

Organ‐specific redox imbalances in spinal muscular atrophy mice are partially rescued by SMN antisense oligonucleotides

FEBS Letters, EarlyView.
We identified a systemic, progressive loss of protein S‐glutathionylation—detected by nonreducing western blotting—alongside dysregulation of glutathione‐cycle enzymes in both neuronal and peripheral tissues of Taiwanese SMA mice. These alterations were partially rescued by SMN antisense oligonucleotide therapy, revealing persistent redox imbalance as ...
Sofia Vrettou, Brunhilde Wirth
wiley   +1 more source

Spatial differences of dissolved organic matter composition and humification in an artificial lake

Water Science and Technology
The depth-dependent dynamics of dissolved organic matter (DOM) structure and humification in an artificial lake limits the understanding of lake eutrophication and carbon cycling. Using fluorescence regional integration (FRI) and parallel factor analysis
Jin Zhang, Jiajia Tan, Yingjie Wang
doaj   +1 more source

Performance Analysis of Parallel Pollard's Rho Factoring Algorithm

International Journal of Computer Science and Information Technology, 2013
Integer factorization is one of the vital algorithms discussed as a part of analysis of any black-box cipher suites where the cipher algorithm is based on number theory. The origin of the problem is from Discrete Logarithmic Problem which appears under the analysis of the cryptographic algorithms as seen by a cryptanalyst.
Anjan K Koundinya, Harish G, Srinath N K, Raghavendra G E, Pramod Y V, Sandeep R, Punith Kumar G   +6 more
openaire   +1 more source

Blind Spectral Decomposition of Single-Cell Fluorescence by Parallel Factor Analysis [PDF]

Biophysical Journal, 2004
Simultaneous measurement of multiple signaling molecules is essential to investigate their relations and interactions in living cells. Although a wide variety of fluorescent probes are currently available, the number of probes that can be applied simultaneously is often limited by the overlaps among their fluorescence spectra.
Shirakawa, Hideki, Miyazaki, Shunichi
openaire   +2 more sources

Transferrin receptor 1‐mediated iron uptake supports thermogenic activation in human cervical‐derived adipocytes

FEBS Letters, EarlyView.
In this study, we found that human cervical‐derived adipocytes maintain intracellular iron level by regulating the expression of iron transport‐related proteins during adrenergic stimulation. Melanotransferrin is predicted to interact with transferrin receptor 1 based on in silico analysis.
Rahaf Alrifai, Mizuki Seo, Gyath Karadsheh, Fachrur Rizal Mahendra, Máté Á Demény, Ferenc Győry, János András Mótyán, László Fésüs, Endre Kristóf, Rini Arianti   +9 more
wiley   +1 more source

Characterizing Soil Dissolved Organic Matter Across a Permafrost Thaw Gradient (Continuous to Isolated Patches) in Northeastern China

Ecology and Evolution
Permafrost zones are currently experiencing rapid warming, and dissolved organic matter (DOM) is a potentially important pathway for carbon release from permafrost after thawing.
Siyuan Zou, Xiaodong Wu, Jiawei Zhang, Nannan Zhang, Xiangwen Wu, Shuying Zang   +5 more
doaj   +1 more source

Fluorescence spectroscopy for tracking microbiological contamination in urban waterbodies

Frontiers in Water
Dissolved organic matter (DOM) plays a crucial role in freshwater ecosystem function. Monitoring of DOM in aquatic environments can be achieved by using fluorescence spectroscopy.
Natália Angelotti de Ponte Rodrigues, Natália Angelotti de Ponte Rodrigues, Rémi Carmigniani, Arthur Guillot-Le Goff, Arthur Guillot-Le Goff, Françoise S. Lucas, Claire Therial, Manel Naloufi, Aurélie Janne, Francesco Piccioni, Mohamed Saad, Philippe Dubois, Brigitte Vinçon-Leite   +12 more
doaj   +1 more source